The Yin and Yang of Inflammation.

The Yin and Yang of Inflammation.
Curr Mol Med. 2014 Oct 15;
Authors: Blackman MA, Yates JL, Spencer CM, Vomhof-DeKrey EE, Cooper AM, Leadbetter EA
Abstract
Stroke is a complex disease resulting from the interplay of genetics and environment. In some instances (mainly in young adults) stroke is the direct result of a monogenic disease. Among the monogenic causes of stroke, the diseases which are most frequently encountered in the adult general neurological practice are CADASIL, Fabry and mitochondrial diseases. Brain MRI and clinical features may frequently lead to a correct molecular diagnosis. Here we review the single-gene causes of ischemic stroke, with special regard to the associated features which may help in the diagnostic approach.
PMID: 25323997 [PubMed - as supplied by publisher]

Source: Current Molecular Medicine - October 15, 2014 Category: Molecular Biology Authors: Blackman MA, Yates JL, Spencer CM, Vomhof-DeKrey EE, Cooper AM, Leadbetter EA Tags: Curr Mol Med Source Type: research