Activation of pro-survival metabolic networks by 1,25(OH) 2 D 3 does not hamper the sensitivity of breast cancer cells to chemotherapeutics

ConclusionsAltogether, we propose that regulation of energy metabolism contributes to 1,25(OH)2D3’s anti-cancer effects and that combining 1,25(OH)2D3 with drugs targeting metabolic networks in tumor cells may lead to synergistic effects.
Source: Cancer and Metabolism - Category: Cancer & Oncology Source Type: research