Involvement of vascular endothelial growth factor (VEGF) and mitogen-activated protein kinases (MAPK) in the mechanism of neuroleptic drugs.

CONCLUSION: The obtained results suggest that haloperidol and olanzapine can trigger the MAPK and VEGF signaling pathway, which may contribute to their neuroprotective mechanism of action. PMID: 30144664 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30144664?dopt=Abstract

Source: Pharmacological Reports - August 22, 2018 Category: Drugs & Pharmacology Authors: Jóźwiak-Bębenista M, Jasińska-Stroschein M, Kowalczyk E Tags: Pharmacol Rep Source Type: research