Managing recurrent urinary tract infections in kidney transplant patients.

Managing recurrent urinary tract infections in kidney transplant patients.
Expert Rev Anti Infect Ther. 2018 Aug 09;:
Authors: Bodro M, Linares L, Chiang D, Moreno A, Cervera C
Abstract
INTRODUCTION: Recurrent urinary tract infections are a common clinical problem in kidney transplant recipients. Due to the complex urological anatomy derived from the implantation of the kidney graft, the spectrum of the disease and the broad underlying pathophysiological mechanisms. Recurrent urinary infections worsen the quality of life, decrease the graft survival and increase the costs of kidney transplantation. Areas covered. In this review we describe the definitions, clinical characteristics, pathophysiological mechanisms and microbiology of recurrent urinary tract infections in kidney transplantations. The actual published literature on the management of recurrent urinary tract infections is based on case series, observational cohorts and very few clinical trials. In this review, the available evidence is compiled to propose evidence-based strategies to manage these complex cases. Expert commentary. The management of recurrent urinary tract infections in kidney transplant patients requires a proper diagnosis of the underlying mechanism. Early identification of structural or functional urological abnormalities, potentially amenable for surgical correction, is crucial for a successful management. The use of antibiotics to prevent recurrent infec...

Source: Expert Review of Anti-Infective Therapy - August 11, 2018 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research