Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy

ConclusionsThe results lead us to suggest a regulatory role forCR1 polymorphisms on mRNA and sCR1 levels, with haplotype-specific effects increasing susceptibility to leprosy, probably by enhancing parasite phagocytosis and inflammation.

Source: PLoS Neglected Tropical Diseases - August 9, 2018 Category: Tropical Medicine Authors: Gabriela Canalli Kretzschmar Source Type: research