Graves ’ disease and celiac disease in a patient with myotonic dystrophy type 2

Myotonic dystrophy type 2 (DM2) is a dominantly inherited multisystem disorder caused by a CCTG repeat expansion in intron 1 of the CNBP gene on chromosome 3q21.3. DM2 is characterized by progressive proximal muscle weakness, myotonia, early-onset cataract, and multiorgan involvement including cardiac conduction abnormalities, gastrointestinal involvement and endocrine disturbances [1]. Autoimmune diseases are more prevalent (21%) and autoantibodies are more frequently detected (25%) in patients with DM2 compared to patients with myotonic dystrophy type 1 and the general population [2].
Source: Neuromuscular Disorders - Category: Neurology Authors: Tags: Case report Source Type: research