MiR-298 Exacerbates Ischemia/Reperfusion Injury Following Ischemic Stroke by Targeting Act1

Conclusions: Upregulation of miR-298 following ischemic stroke promotes brain injuryin vitro and vivo by inhibiting the Act1/JNK/NF- κB signaling cascade and the downstream autophagy pathway. Therapeutic strategies that target miR-298 could be beneficial for the treatment of ischemic stroke.Cell Physiol Biochem 2018;48:528 –539

https://www.karger.com/Article/FullText/491810

Source: Cellular Physiology and Biochemistry - July 18, 2018 Category: Cytology Source Type: research