Irinotecan delivery by unimolecular micelles composed of reduction-responsive star-like polymeric prodrug with high drug loading for enhanced cancer therapy

This study demonstrated that CPIO carrier could provide a rational design of a stimuli-responsive polymeric prodrug for delivery of irinotecan.Graphical abstractTherapeutic unimolecular micelles extended form β-cyclodextrin conjugated star-like polymer for reductive agent-triggered drug release of irinotecan.
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research