BSA-Based Cu2Se Nanoparticles with Multistimuli-Responsive Drug Vehicles for Synergistic Chemo-Photothermal Therapy
Publication date: Available online 19 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Zhou Liu, Leung Chan, Xiaoting Ye, Yan Bai, Tianfeng ChenAbstractFunctionalized-nanoparticles have been developed as novel therapeutic delivery platform for simultaneous drug loading and therapy over the past decade. Rationally-designed biocompatible nanosystem simultaneously with multistimuli-responsive property and synergistic therapeutic potential are highly desirable for modern biological applications. Herein, Cu2Se nanoparticles (Cu2SeNPs) with suitable size have been functionalized by bull serum albumin (BSA) throu...
Source: Colloids and Surfaces B: Biointerfaces - July 20, 2018 Category: Biochemistry Source Type: research

Adhesion and Stiffness of Biotin-Superavidin Bonds
Publication date: Available online 19 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Bahman Farzi, Jan Scrimgeour, Cetin CetinkayaAbstractA non-invasive vibrational spectroscopy technique is introduced and utilized to characterize the average spring constant of a single Superavidin (SAv)-Biotin (Bi).polyethylene glycol (PEG) ligand receptor complex as well as the effective Young’s modulus and adhesion of a layer formed by the SAv-Bi.PEG ligand-receptors. In the reported experiments, SAv coated Polystyrene (PS) particles are deposited on a layer of Bi.PEG receptors, bound to a silicon (Si) substrate...
Source: Colloids and Surfaces B: Biointerfaces - July 20, 2018 Category: Biochemistry Source Type: research

Detailed characterization of POSS-poly(ethylene glycol) interaction with model phospholipid membrane at the air/water interface
Publication date: 1 November 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 171Author(s): Marta Skrzypiec, Krystyna ProchaskaAbstractPolyhedral oligomeric silsesquioxanes (POSS) derivatives have been receiving remarkable attention due to their potential biomedical application and therefore understanding molecular mechanism of their interaction with cell membranes should be studied at molecular level. Here we investigate the binary mixture of an open silsesquioxane cage POSS-poly(ethylene glycol) (POSS-PEG) and 1,2-myristoyl-sn-glycero-3-phosphoethanolamine (DMPE) as a representative of phospholipid located in b...
Source: Colloids and Surfaces B: Biointerfaces - July 19, 2018 Category: Biochemistry Source Type: research

Fluorescent activatable gadofullerene nanoprobes as NIR-MR dual-modal in vivo imaging contrast agent
Publication date: 1 November 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 171Author(s): Cheng Li, Huan Huang, Rongli Cui, Juan Li, Xihong Guo, Huanli Yao, Bing Liu, Binggang Xu, Ying Li, Shuaichao Liu, Jinquan Dong, Gengmei Xing, Baoyun SunAbstractDual mode imaging technology is widely developed to achieve the early-stage precision cancer diagnosis. Here we designed a dual-modal magnetic resonance/near infrared fluorescence optical imaging contrast agent (GdF-SS-NIR783) with the fluorescence activatable and safer gadofullerene. The nanoprobes were fabricated by conjugating the gadofullerene derivatives with a...
Source: Colloids and Surfaces B: Biointerfaces - July 19, 2018 Category: Biochemistry Source Type: research

Reduced inflammatory response by incorporating magnesium into porous TiO2 coating on titanium substrate
Publication date: Available online 17 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Xuezhong Li, Qianli Huang, Ling Liu, Weihong Zhu, Tarek A. Elkhooly, Yong Liu, Qingling Feng, Qingxiang Li, Shaoqiang Zhou, Yin Liu, Hong WuAbstractThe implant materials with proper anti-inflammatory and osteogenic properties may be promising for orthopedic applications. The inflammatory response induced by biomaterials has been regarded as one of the critical factors in determining in vivo fate of implants. Therefore, a novel bone biomaterial should have inflammation regulatory effects instead of being completely bio-in...
Source: Colloids and Surfaces B: Biointerfaces - July 18, 2018 Category: Biochemistry Source Type: research

The elucidation of surrounding alginate gels on the pollutants degradation by entrapped nanoscale zero-valent iron
Publication date: Available online 17 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Kexin Yi, Zhixuan Fan, Jinping Tang, Anwei Chen, Jihai Shao, Liang Peng, Qingru Zeng, Si LuoAbstractThe adsorption capacity of calcium alginate (Ca-alginate) beads was evaluated by measuring the removal of three organic compounds with different charges (malachite green, p-chlophenol and methyl orange). The diffusion was investigated in Ca-alginate hydrogel as a function of solute charge. It was found that an increased electrostatic attraction between the hydrogel and solute would improve the mobility of solute and hence ...
Source: Colloids and Surfaces B: Biointerfaces - July 18, 2018 Category: Biochemistry Source Type: research

Functionalization of Graphene Family Nanomaterials for Application in Cancer Therapy
Publication date: Available online 17 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Duarte de Melo-Diogo, Rita Lima-Sousa, Cátia G. Alves, Elisabete C. Costa, Ricardo O. Louro, Ilídio J. CorreiaAbstractGraphene family nanomaterials’ (GFN) ability to interact with near-infrared light has propelled their application in cancer photothermal therapy. Furthermore, the graphitic lattice of GFN can adsorb different types of molecules, which has motivated their use in cancer drug delivery. However, the direct application of GFN in cancer therapy is severely hindered by their poor colloidal st...
Source: Colloids and Surfaces B: Biointerfaces - July 18, 2018 Category: Biochemistry Source Type: research

Effects of the multilayer structures on Exenatide release and bioactivity in microsphere/thermosensitive hydrogel system
Publication date: 1 November 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 171Author(s): Puxiu Wang, Yue li, Mingyan JiangAbstractTraditional polypeptide-loaded PLGA microspheres (PM) using emulsion electrospray techniques often exhibit unsteady release and limited bioactivity. To solve these two problems, an Exenatide (EXT)-loaded multilayer system composed ofPM and thermosensitive hydrogel was prepared by the emulsion electrospray technique in this study. Hydrogel mixture were loaded in PLGA microspheres as Depot-hydrogel to prepare Gel/PM. The PM/Gel and Gel/PM/Gel systems were obtained by dispersion of PM ...
Source: Colloids and Surfaces B: Biointerfaces - July 14, 2018 Category: Biochemistry Source Type: research

Loss of Integrity of Doxorubicin Liposomes during Transcellular Transportation Evidenced by Fluorescence Resonance Energy Transfer Effect
Publication date: Available online 11 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Dong Li, Jie Zhuang, Yinqian Yang, Dandan Wang, Jinlong Yang, Haisheng He, Wufa Fan, Amrita Banerjee, Yi Lu, Wei Wu, Li Gan, Jianping QiABSTRACTThe aim of this work was to elucidate the influence of liposome characteristics on the transcellular process by in vitro studies that would enable designing more efficient oral formulations. Various liposomes with different properties were prepared, including 100 - 500 nm, anionic, cationic and PEGylated liposomes. All liposomes were labeled by fluorescence resonance energy tra...
Source: Colloids and Surfaces B: Biointerfaces - July 12, 2018 Category: Biochemistry Source Type: research

Development of functionalized gold nanoparticles as nanoflare probes for rapid detection of classical swine fever virus
Publication date: Available online 11 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Pengbo Ning, Zhongxing Wu, Xuepeng Li, Yulu Zhou, Aoxue Hu, Xiaocheng Gong, Jun He, Yuqiong Xia, Kangkang Guo, Ruili Zhang, Xianghan Zhang, Zhongliang WangAbstractClassical swine fever (CSF) is a devastating viral disease affecting pigs that causes major economic losses worldwide. Conventional assays to identify classical swine fever virus (CSFV) face challenges, such as the required molecular amplification of the target molecules via polymerase chain reaction (PCR). We designed a gold nanoflare probe to directly detect ...
Source: Colloids and Surfaces B: Biointerfaces - July 12, 2018 Category: Biochemistry Source Type: research

Substrate stiffness affects neural network activity in an extracellular matrix proteins dependent manner
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Yu-Qiao Wen, Xiaohui Gao, Aiping Wang, Yu Yang, Sisi Liu, Zhang Yu, Guan-Bing Song, Hu-Cheng ZhaoAbstractNeuronal growth, differentiation, extension, branching and neural network activity are strongly influenced by the mechanical property of extracellular matrix (ECM). However, the mechanism by which substrate stiffness regulates a neural network activity, and the importance of ECM composition in conferring substrate stiffness sensing have not been explored. To address this question, the hippocampal neurons were seeded on t...
Source: Colloids and Surfaces B: Biointerfaces - July 12, 2018 Category: Biochemistry Source Type: research

Dual temperature and pH responsive nanofiber formulations prepared by electrospinning
This study therefore demonstrates that PNVCL/EC/KET-Eudragit/KET multicomponent fiber mats comprise effective and biocompatible materials for targeted drug delivery.Graphical Abstract (Source: Colloids and Surfaces B: Biointerfaces)
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Migration critically meditates osteoblastic differentiation of bone mesenchymal stem cells through activating canonical Wnt signal pathway
In this study, we used RGD-modified substrates to regulate cell motility though different RGD concentrations and systematically analyzed the correlation between osteoblastic differentiation and cell migration, as well as the role of Wnt signaling pathway. High motility correlated well with the significantly enhanced potential of the MSCs to differentiate into the osteoblastic lineage, as suggested by the significant up-regulations of Runx2, ALP, OCN expressions. The results also suggested that enhanced MSC migration efficiently activated the canonical Wnt-β-catenin pathway and stimulated transcription activities leadi...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Beta-carotene-bound albumin nanoparticles modified with chlorin e6 for breast tumor ablation based on photodynamic therapy
Publication date: Available online 10 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Pham Thi Thu Phuong, Sungin Lee, Changkyu Lee, Bohyung Seo, Sanghyun Park, Kyung Taek Oh, Eun Seong Lee, Han-Gon Choi, Beom Soo Shin, Yu Seok YounAbstractChlorin e6 (Ce6) has attracted considerable interest as a promising second-generation photosensitizer for photodynamic therapy (PDT). However, the in vivo availability of Ce6 is significantly restricted by its low water solubility and poor ability to target tumors. We sought to overcome the limitations of Ce6 by using albumin nanoparticles with nabTM (nanoparticle album...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Mathematical models and fractal analysis for the investigation of the photodynamic inactivation in phytopathogenic microorganisms
Publication date: Available online 10 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Alessandro S. Kalck, Maria F. Costa Pedro, Kevin F. dos Santos, Marcos S. Sousa, Josmary R. Silva, Nara C. de SouzaABSTRACTThe increasing and indiscriminate use of pesticides may lead to the intoxication and contamination of the environment and foods. In addition, pesticides can cause fungal resistance promoting the selection of resistant phytopathogenic fungi. This is a problem in the agricultural and human health areas, which leads to a need for developing new methodologies to address this problem. Photodynamic inactiv...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Development and Evaluation of a Spray Applicator for Platelet-Rich Plasma
In this study, we present a compact and self-contained spraying device without external connections such as a power supply or compressor. The biocompatible propellant R134a is used to aspirate and atomize the blood derivatives. A 3D-printed, two-substance nozzle functions as the operating unit, throttle, mixing zone and atomization unit. The spray characteristics were evaluated via experimental flow volume, cone and droplet size measurements. Biological evaluation was performed by flow cytometry comparing platelet activation in the blood derivatives before and after spraying, and PDGF ELISA comparing growth factor release,...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Preparation of self-assembled platinum nanoclusters to combat Salmonella typhi infection and inhibit biofilm formation
Publication date: Available online 11 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Siva Bala Subramanian, Anugraha Ramani, V. Ganapathy, Veerappan AnbazhaganAbstractIn this work, phytoprotein functionalized platinum nanoparticles (PtNCs) were synthesized using the proteins from fresh green spinach leaves. Transmission electron microscopy showed that PtNCs were spherical shape with size ~ 5 nm, which self assembled into spherical platinum nanoclustures (PtNCs) with size within the range of 100 - 250 nm. The presence of elemental platinum was confirmed by EDX analysis. FTIR studies confirm that the P...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Hyaluronan magnetic nanoparticle for mitoxantrone delivery toward CD44-positive cancer cells
Publication date: Available online 11 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Azam Sargazi, Fereshteh Shiri, Sheida Keikha, Mostafa Heidari MajdAbstractHyaluronic acid (HA) is increasingly investigated for biomedical applications such as regenerative medicine, aesthetic medicine, and drug delivery. Accordingly, conjugation of HA to PEGylated MNPs could increase the active targeting ability of nano-drug carriers toward CD44 receptors and be useful in a clinical setting such as drug delivery. So, we chemically conjugated mitoxantrone (MTX) to HA-PEGylated MNPs to use concurrent advantages such as pr...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Thymus essential oil extraction, characterization and incorporation in phospholipid vesicles for the antioxidant/antibacterial treatment of oral cavity diseases
Publication date: Available online 11 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Maria Manconi, Giacomo Petretto, Guy D’hallewin, Elvira Escribano, Egle Milia, Roberto Pinna, Alessandra Palmieri, Mohammad Firoznezhad, Josè Esteban Peris, Iris Usach, Anna Maria Fadda, Carla Caddeo, Maria Letizia MancaABSTRACTThe aim of the work was to extract, characterize, and formulate Thymus capitatus (Tymbra capitata) essential oil in phospholipid vesicles: liposomes, glycerosomes and Penetration Enhancer-containing Vesicles (PEVs).The steam-distilled essential oil was mainly composed of carvacrol. Th...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Three-dimensional alginate hydrogels for radiobiological and metabolic studies of cancer cells
Publication date: Available online 18 June 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Graham H. Read, Natsuko Miura, Jenna L. Carter, Kelsey T. Kines, Kazutoshi Yamamoto, Nallathamby Devasahayam, Jason Y. Cheng, Kevin A. Camphausen, Murali C. Krishna, Aparna H. KesarwalaAbstractThe purpose of this study is to demonstrate calcium alginate hydrogels as a system for in vitro radiobiological and metabolic studies of cancer cells. Previous studies have established calcium alginate as a versatile three-dimensional (3D) culturing system capable of generating areas of oxygen heterogeneity and modeling metabolic c...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Electrochemically grown functionalized -Multi-walled carbon nanotubes/hydroxyapatite hybrids on surgical grade 316L SS with enhanced corrosion resistance and bioactivity
Publication date: Available online 28 June 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Stango S. Arul Xavier, Vijayalakshmi U.AbstractCoatings using functionalized multi-walled carbon nanotubes (f-MWCNTs)/hydroxyapatite (HAP) on 316 L Stainless Steel by electrodeposition at the parameter of “-1.5 V” for 30 min. with three electrode set-up configuration and optimization of various concentrations of f-MWCNTs from 1 to 5% were done to improve the coating characteristics for future biomedical applications. The obtained coatings were characterized by Fourier Transformed-Infra Red spectroscopy ...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Vesicles from the Self-Assembly of the Ultra-small Fatty Acids with Amino Acids under Aqueous Conditions
In this study, the self-assembly process of the amphiphilic structures formed by the interaction between ultra-small fatty acids [FAs, Cn (n = 4-8)] and amino acids (AAs) to generate vesicles under aqueous conditions were investigated in detail, along with the corresponding dynamic vesiculation mechanisms. Our results showed that the molar ratio of FAs/AAs and the chain length of FAs largely affected the structural characteristics and dispersion of vesicles. The detailed information about the entire size distributions and morphology of obtained vesicles were explored by the cryogenic transmission electron microscopy (C...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Volume expansion of erythrocytes is not the only mechanism responsible for the protection by arginine-based surfactants against hypotonic hemolysis
Publication date: Available online 4 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): M. Elisa Fait, Melisa Hermet, Romina Vazquez, Sabina Mate, M. Antonieta Daza Millone, M. Elena Vela, Susana R. Morcelle, Laura BakasABSTRACTA novel arginine-based cationic surfactant Nα-benzoyl-arginine dodecylamide (Bz-Arg-NHC12) was synthesized in our laboratory. In this paper we study the interaction of Bz-Arg-NHC12 with sheep and human red blood cells (SRBC and HRBC respectively) due to their different membrane physicochemical/biophysical properties. SRBC demonstrated to be slightly more resistant than HRBC to t...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Surface modification of nanoporous anodic titanium dioxide layers for drug delivery systems and enhanced SAOS-2 cell response
Publication date: Available online 6 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Anna Pawlik, Robert P. Socha, Marie Hubalek Kalbacova, Grzegorz D. SulkaAbstractNowadays, titanium and its alloys are the most commonly used implantable materials. The surface topography and chemistry of titanium-based implants are responsible for osseointegration. One of the methods to improve biocompatibility of Ti implants is a modification with sodium hydroxide (NaOH) or 3-aminopropyltriethoxysilane (APTES). In the present study, anodic titanium dioxide (ATO) layers were electrochemically fabricated, and then immersed...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Monoolein liquid crystalline phases for topical delivery of crocetin
Publication date: Available online 6 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Elisabetta Esposito, Federica Carducci, Paolo Mariani, Nicolas Huang, Fanny Simelière, Rita Cortesi, Giuseppe Romeo, Carmelo PugliaAbstractThe present investigation concerns the production and characterization of monoolein-water systems designed for cutaneous administration of crocetin. The different monoolein crystalline phases forming in the presence of crocetin as a function of added water have been investigated by x-ray and polarized light microscopy. Franz cell was employed to compare in vitro the crocetin dif...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

An antibody-based platform for melatonin quantification
Publication date: Available online 7 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Laís C. Brazaca, Camila B. Bramorski, Juliana Cancino-Bernardi, Sanseray da Silveira Cruz-Machado, Regina P. Markus, Bruno C. Janegitz, Valtencir ZucolottoAbstractMelatonin, the ‘chemical signal of darkness’, is responsible to regulate biological rhythms and different physiological processes. It is mainly produced by the pineal gland as a hormone in a rhythmic daily basis, but it may also be synthesized by other tissues, such as immune cells, under inflammatory conditions. Its abnormal circulating level...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Rapid mussel-inspired synthesis of PDA-Zn-Ag nanofilms on TiO2 nanotubes for optimizing the antibacterial activity and biocompatibility by doping polydopamine with zinc at a higher temperature
In this study, a rapid polymerization of dopamine was achieved by performing the reaction in a water bath at 90 °C (PDA-H). Furthermore, the reduction of Ag+ ions was markedly accelerated by the PDA-Zn film that was formed on the surface of TiO2 NTs from a solution of dopamine and zinc nitrate under the same heating conditions. The reaction between the PDA-Zn film and silver nitrate was dramatically reduced to 10 min, and the silver nanoparticles deposited on the PDA-Zn film were more uniform than those by PDA-H film. This PDA-Zn-Ag-TiO2 NTs material exhibited good antibacterial activity, as evidenced by the inhibi...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Gold Modified Polydopamine Coated Mesoporous Silica Nano-Structures for Synergetic Chemo-Photothermal Effect
Publication date: Available online 10 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Nahla Rahoui, Bo Jiang, Mohammad Hegazy, Nadia Taloub, Yuanlin Wang, Miao Yu, Yu Dong HuangAbstractNear infrared (NIR) responsive agents have attracted a great attention in nanomedicine due to their efficient photothermal effect (PTE) and eco-friendly nature. In our study, a novel kind of nanostructure were developed based on mesoporous silica nanoparticles (MSN) loaded doxorubicin(DOX) core and polydopamine-gold nanoparticles shell (PDA-AuNPs), the system was designed for combined chemo and photothermal therapy into one...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Regulation of osteogenesis by micro/nano hierarchical titanium surfaces through a Rock-Wnt5a feedback loop
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Yonglin Yu, Xinkun Shen, Junjie Liu, Yan Hu, Qichun Ran, Caiyun Mu, Kaiyong CaiAbstractTitanium substrates with micro/nano hierarchical features could positively mediate the osteogenesis of a titanium implant; nevertheless, the underlying molecular mechanism needs to be further revealed. In this work, we fabricated a micro/nano hierarchically structured Ti (MNT) sample and attempted to evaluate its topography-mediated biological effects and potential molecular mechanisms in vitro. The results proved that MNT could not only ...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Protection of dopamine towards autoxidation reaction by encapsulation into non-coated- or chitosan- or thiolated chitosan-coated-liposomes
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): A. Trapani, D. Mandracchia, G. Tripodo, S. Cometa, S. Cellamare, E. De Giglio, P. Klepetsanis, S.G. AntimisiarisAbstractThe aim of this work is to evaluate the potential of non-coated-, chitosan-(CS)- or chitosan-glutathione conjugate- (CS-GSH)-coated liposomes to protect the neurotransmitter Dopamine (DA) from the autoxidation reaction in neutral/alkaline conditions. This may be of interest in the development of nanotechnology-based approaches to improve Parkinson’s disease treatment because decreased ROS production ...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

A comprehensive review on green nanomaterials using biological systems: Recent perception and their future applications
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Rijuta Ganesh Saratale, Indira Karuppusamy, Ganesh Dattatraya Saratale, Arivalagan Pugazhendhi, Gopalakrishanan Kumar, Yooheon Park, Gajanan S. Ghodake, Ram Naresh Bharagava, J. Rajesh Banu, Han Seung ShinAbstractOver the last few years, nanotechnology is increasingly developing in scientific sector, which has attracted a great deal of interest because of its abundant applications in almost all the areas. In recent times, green nanotechnology is a relative and multidisciplinary field that has emerged as a rapidly developing...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Association and sequestered dissociation of an anticancer drug from liposome membrane: Role of hydrophobic hydration
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Bijan K. Paul, Narayani Ghosh, Saptarshi MukherjeeAbstractHerein, the interaction of a potent anticancer drug (Sanguinarine, SG) with dimyristoyl-l-α-phosphatidylglycerol (DMPG) liposome membrane has been investigated at physiological pH. The spectroscopic fluorescence decay results demonstrate a modification of the photophysics of SG within DMPG-encapsulated state leading to preferential stabilization of the iminium ion over the alkanolamine form. This suggests a key role of electrostatic force underlying the interac...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Interfacial reinforcement in a poly-l-lactic acid/mesoporous bioactive glass scaffold via polydopamine
This study suggested that the PLLA/p-MBG scaffold may have a potential application in tissue engineering.Graphical abstractGraphical abstract demonstrated the preparation and performance tests of poly-l-lactic acid (PLLA)-based scaffolds. Polydopamine modified mesoporous bioactive glass (p-MBG) was prepared by oxidation self-polymerization of dopamine in a tris(hydroxymethyl) aminomethane hydrochloride buffer solution (Tris-HCL). Scaffolds were prepared by selective laser sintering process (SLS). (Source: Colloids and Surfaces B: Biointerfaces)
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

The fabrication and in vitro properties of antibacterial polydopamine-LL-37-POPC coatings on micro-arc oxidized titanium
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Ye He, Yangyang Zhang, Xinkun Shen, Bailong Tao, Ju Liu, Zhang Yuan, Kaiyong CaiAbstractBacterial infection commonly occurs in clinical settings when the procedure involves a medical implant. Thus, the fabrication of antimicrobial medical materials has attracted much attention in recent years. To improve the antibacterial properties of titanium (Ti)-based biomedical materials, surface microporous structures, with antimicrobial peptide coatings, were employed in this study. Native Ti substrates were endowed with a certain le...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Characterizations of hyaluronate-based terpolymeric hydrogel synthesized via free radical polymerization mechanism for biomedical applications
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Dipankar Das, Thi Thu Hien Pham, Insup NohAbstractIn the present study, a novel terpolymeric hydrogel was developed using sodium hyaluronate (HA), 2-hydroxyethyl acrylate (2-HEA), and poly(ethylene glycol) diacrylate (PEGDA) via free radical polymerization for biomedical applications. To achieve elasticity, swelling ability, porous architecture and sufficient gel strength, hyaluronate was chemically modified by grafting and crosslinking methods using 2-HEA and PEGDA, respectively. The structure and compositions of the fabri...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Solvent-free and one-pot synthesis of silver and zinc oxide nanoparticles: Activity toward cell membrane component and insulin signaling pathway in experimental diabetes
ConclusionAgNPs and ZnONPs represent promising materials in attenuating diabetic complications and insulin resistance in experimental diabetes; no Impressive differences were observed between the effect of ZnONPs and AgNPs in this current research.Graphical abstract (Source: Colloids and Surfaces B: Biointerfaces)
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Simultaneous two drugs release form Janus particles prepared via polymerization-induced phase separation approach
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Elham Dehghani, Mehdi Salami-Kalajahi, Hossein Roghani-MamaqaniAbstractSeeded emulsion polymerization of 2-dimethylaminoethylamino methacrylate (DMAEMA) was carried out using monodispersed poly(2-hydroxyehtyl methacrylate) (PHEMA) seeds to produce Janus particles. Three feeding approaches were used comprising one together, rest and continuous feeding methods to investigate different morphologies. However, FE-SEM results showed that all feeding approaches yielded dumbbell-like Janus particles. Furthermore, snowman-like Janus...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Bacterial adhesion and inactivation on Ag decorated TiO2-nanotubes under visible light: Effect of the nanotubes geometry on the photocatalytic activity
This study investigates the effect of the diameter of TiO2 nanotubes and silver decorated nanotubes on optical properties and photocatalytic inactivation of Escherichia coli under visible light. The TiO2 nanotubes (TiO2-NTs) were prepared using the electrochemical method varying the anodization potential starting from 20 V until 70 V. The Ag nanoparticles were carried out using the photoreduction process under the same experimental conditions. The diameter size was determined using the scanning electronic microscopy (SEM). TiO2-NTs diameter reached ∼100 nm at 70 V. Transmission electronic microscopy (TEM) imagi...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

In vitro assessment of antimicrobial and genotoxic effect of metallosurfactant based nickel hydroxide nanoparticles against Escherichia coli and its genomic DNA
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Varsha Dogra, Gurpreet Kaur, Amanpuneet Kaur, Rajeev Kumar, Sandeep KumarAbstractIn the present study, we have synthesized nickel hydroxide nanosuspensions (Ns) using microemulsion technique. This approach is eco-friendly and makes use of Tween 80 (a non-ionic biocompatible surfactant) and newly synthesized metallosurfactants for the formation of uniform nanoparticles in the form of nanosuspensions (Ns). The nickel hydroxide Ns’s were derived from three different metallosurfactants i.e. NiCTAC (Bishexadecyltrimethylam...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

An electrochemical sensor for homocysteine detection using gold nanoparticle incorporated reduced graphene oxide
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Rajendran Rajaram, Jayaraman MathiyarasuAbstractIn this work, we report a methodology for the quantification of Homocysteine (HcySH) at neutral pH (pH-7.0) using Au nanoparticles incorporated reduced graphene oxide (AuNP/rGO/GCE) modified glassy carbon electrode. The modified electrode was characterized using SEM and XRD techniques. The electrode exhibited a typical behavior against the standard redox probe [Fe(CN)6]3−/4− and resulted in 0.06 V peak to peak potential value. The modified electrode exhibited ele...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Synthesis and antidiabetic properties of chitosan-stabilized selenium nanoparticles
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Siqi Zeng, Yu Ke, Yixi Liu, Yingbin Shen, Lan Zhang, Cheng Li, Aiping Liu, Li Shen, Xinjie Hu, Hejun Wu, Wenjuan Wu, Yuntao LiuAbstractChitosan-stabilized selenium nanoparticles (CTS-SeNPs) were prepared through the reduction of selenite acid with ascorbic acid. The optimal synthesis conditions of CTS-SeNPs were obtained by orthogonal experiments. Besides, the size, morphology and stability of CTS-SeNPs were characterized by transmission electron microscopy (TEM), scanning electron microscope (SEM) and dynamic light scatter...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Amine functional magnetic nanoparticles via waterborne thiol–ene suspension photopolymerization for antibody immobilization
In this study, for the very first time waterborne TESP was performed in the presence of MNPs. Neat MNPs were coated and in situ functionalized with amine groups by using thiol-ene chemistry. Engrailed-2 (EN2) protein, a potential biomarker for various cancers such as prostate cancer, bladder cancer, breast cancer and ovarian cancer, is known to be a strong binder to a specific DNA sequence (50-TAATTA-30) to regulate transcription. Anti-EN2 antibodies were immobilized onto these MNPs by physical adsorption and covalent bonding methods, respectively. The amount of the physically immobilized antibodies (0.54 mg/g) were foun...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Effect of ion partitioning on electrostatics of soft particles with volumetrically charged inner core coated with pH-regulated polyelectrolyte layer
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Ardalan Ganjizade, Arman Sadeghi, Seyed Nezameddin AshrafizadehAbstractThe effect of ion partitioning on the electrostatics of a soft particle with a volumetrically charged core and a pH-dependent polyelectrolyte layer (PEL) is numerically investigated. It is observed that, whenever the ion partitioning is noticeable, the soft layer can be fully charged in a broader range of pH. Besides, a higher number density of the PEL functional groups and a lower charge density of the core result in a sharper dependence of the electric...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Fatty acid and quaternary ammonium modified chitosan nanoparticles for insulin delivery
This study demonstrates that the nanoparticles fabricated from fatty acid modified polymer are an effective liver-targeted delivery system of insulin.Graphical abstract (Source: Colloids and Surfaces B: Biointerfaces)
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

An electrochemical Bisphenol F sensor based on ZnO/G nano composite and CTAB surface modified carbon paste electrode architecture
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): G. Manasa, Ronald J. Mascarenhas, Ashis K. Satpati, Basavanakote M. Basavaraja, Sriram KumarAbstractDue to the enforcement of regulatory restrictions to prevent risk to human health from Bisphenol A (BPA), its structural analogue Bisphenol F (BPF) has been introduced into the market as an alternative. But however recent studies describe BPF as an effectual endocrine disruptor. Hence, there is an indispensible need for research concerning BPF human and environmental exposure level. In this work, we have elicited the developm...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Collagen/chitosan/hyaluronic acid – based injectable hydrogels for tissue engineering applications – design, physicochemical and biological characterization
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Adriana Gilarska, Joanna Lewandowska-Łańcucka, Wojciech Horak, Maria NowakowskaAbstractStudies on synthesis, physico-chemical and biological properties of novel biomimetic materials, potentially useful as injectable hydrogels are presented. These materials are in situ prepared chemically crosslinked collagen/chitosan/hyaluronic acid-based hydrogels exhibiting potential for tissue regeneration. Optimization of hydrogels involved testing the effect of various concentration of crosslinking agent (genipin) as well as differen...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Real-time imaging tracking of a dual-fluorescent drug delivery system based on doxorubicin-loaded globin- polyethylenimine nanoparticles for visible tumor therapy
In this study, the Doxorubicin loaded genipin-crosslinked globin and PEI nanoparticles (Gb-G-PEI/Dox NPs) were designed as a dual fluorescent drug delivery system to track the drug release and carrier degradation process. Both confocal laser scanning microscopy and flow cytometric results showed that Gb-G-PEI/Dox NPs had a higher cellular uptake efficiency than Doxorubicin in the Bel-7402 cell line due to its small size and positively charged surface. The in vivo metabolism experiments tracked by the multispectral fluorescence imaging system elucidated the sustained drug release and carrier degradation process of the Gb-G-...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Ultrasonic fabrication of flexible antibacterial ZnO nanopillar array film
Publication date: 1 October 2018Source: Colloids and Surfaces B: Biointerfaces, Volume 170Author(s): Kwang Se Lee, Chi Hyun Kim, Soon Woo Jeong, Younseong Song, Nam Ho Bae, Seok Jae Lee, Kyoung G. LeeAbstractAntibacterial activity is essential and highly demanded in worldwide to prevent potential bacterial infection. Here in this work, we report a new approch for the fabrication of flexible zinc oxide nanopillar arrays (ZG-NPA) film with an efficient antibacterial activity. A flexible NPA film served as a substrate for the rapid formation of ZnO by using ultrasound-assisted method. The enhancement of antibacterial activity...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

Modulation of serum albumin protein corona for exploring cellular behaviors of fattigation-platform nanoparticles
In this study, the effect of bovine serum albumin (BSA) on gelatin-oleic nanoparticles’ (GONs) physicochemical properties and cellular uptake were evaluated. Coumarin-6 was used as indicator to track the cellular uptake of GONs. The binding of BSA onto the GON surface increased the size, slightly reduced the negative net charge of the GON, and improved GON stability. The presence of BSA in cell culture media reduced the cellular uptake of BSA-uncoated GONs on human embryonic kidney cells 293 (HEK 293) and human adenocarcinoma alveolar basal epithelial cells (A549) in the media without FBS addition. Pre-coated BSA cor...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research

High dispersed phyto-phospholipid complex/TPGS 1000 with mesoporous silica to enhance oral bioavailability of tanshinol
In this study, a high dispersed phyto- phospholipid complex with mesoporous silica containing TPGS 1000 (TPC-SD) was fabricated using Tanshinol (Tan) as model drug. Phospholipid complex (PC) was employed to improve the n-octanol/water partition coefficient (log P) and apparent permeability coefficients (Papp) of Tan. Mesoporous silica was used to compensate for the negative effects of phospholipid on drug’s dispersion and dissolution owing to its viscosity and poor water-solubility. TPGS 1000, a P-gp inhibitor, was used to block the efflux of Tan. Log P tests showed that the lipophilicity of Tan was significantly enh...
Source: Colloids and Surfaces B: Biointerfaces - July 11, 2018 Category: Biochemistry Source Type: research