Obesity: a health crisis of enormous proportion
Polycystic ovarian syndrome (PCOS), one of the most common endocrine disorders, is associated with diverse health problems including obesity, infertility, metabolic syndrome, uterine cancer, anxiety, and depression. The syndrome is well characterized but the exact etiology is poorly understood. Treatments include lifestyle intervention, medical and surgical therapies, and are tailored to symptoms and treatment goals.
Series Type : Expression profiling by RT-PCROrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
ConclusionIpatasertib exhibited rapid absorption and was dose-proportional over a broad dose range. Ipatasertib appeared to be a moderate CYP3A inhibitor when administered at 600 mg and could be administered with or without food in clinical studies.Trail registrationNCT01090960 (registered March 23, 2010); NCT02536391 (registered August 31, 2015).
ConclusionOur study did not demonstrate a protective role of vitamin E in decreasing the incidence of CIPN in patients receiving taxane-based chemotherapy. However, the recovery from CIPN was much better as compared to the control arm, which may indicate a role for vitamin E in decreasing the duration and severity of CIPN.
POLYCYSTIC ovarian syndrome increases the risk of developing type 2 diabetes. Many symptoms of the former condition are attributed to insulin resistance, South Warwickshire NHS Foundation Trust confirmed.
Millions of Canadian adults are classified as overweight or obese by the Body Mass Index. But according to some experts, the BMI is among many things that should be scrapped as the medical field changes how it looks at obesity.
Dr. Laura Esserman answers the door of her bright yellow Victorian home in San Francisco’s Ashbury neighborhood with a phone at her ear. She’s wrapping up one of several meetings that day with her research team at University of California, San Francisco, where she heads the Carol Franc Buck Breast Care Center. She motions me in and reseats herself at a makeshift home office desk in her living room, sandwiched between a grand piano and set of enormous windows overlooking her front yard’s flower garden. It’s her remote base of operations when she’s not seeing patients or operating at the hospita...
Population - attributable fraction varied from 3.9 percent for urinary bladder cancer to 16.9 percent for stomach cancer
In late August, a radiation oncologist in Tampa, Florida, described a distressing first in his career.Medscape Medical News
Transcranial magnetic stimulation (TMS), a noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain, may help relieve symptoms of depression and posttraumatic stress disorder (PTSD) in veterans, astudyin theJournal of Affective Disorders has found.Michelle R. Madore, Ph.D., of Stanford University School of Medicine and colleagues analyzed data from 770 patients who had major depressive disorder and received at least one TMS session at any of 27 Veterans Administration sites from October 2017 to March 2020. Of these patients, 68.4% also met the criteria for a diagnosis of PTSD. The researchers d...
Patients undergoing gastrointestinal cancer surgery often receive red blood cell (RBC) transfusions. Understanding practice variation is critical to support efforts working towards responsible RBC transfusion use. We aimed to measure the extent and importance of variation in perioperative RBC transfusion use across surgeons and hospitals among gastrointestinal cancer surgery patients.