Regulatory effects of the long non ‑coding RNA RP11‑543N12.1 and microRNA‑324‑3p axis on the neuronal apoptosis induced by the inflammatory reactions of microglia.

In conclusion, RP11‑543N12.1 targeted miR‑324‑3p to suppress proliferation and promote apoptosis in the AD cell model, suggesting that RP11‑543N12.1 and miR‑324‑3p may be potential biomarkers and therapeutic targets for AD. PMID: 29956723 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29956723?dopt=Abstract

Source: International Journal of Molecular Medicine - June 20, 2018 Category: Molecular Biology Authors: Cai M, Wang YW, Xu SH, Qiao S, Shu QF, Du JZ, Li YG, Liu XL Tags: Int J Mol Med Source Type: research