A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease

Conclusions These data reveal a novel signaling mechanism involving NOX4 and TRPC6 in podocytes that could be pharmacologically targeted to abate the development of DKD.

Source: Journal of the American Society of Nephrology : JASN - June 29, 2018 Category: Urology & Nephrology Authors: Ilatovskaya, D. V., Blass, G., Palygin, O., Levchenko, V., Pavlov, T. S., Grzybowski, M. N., Winsor, K., Shuyskiy, L. S., Geurts, A. M., Cowley, A. W., Birnbaumer, L., Staruschenko, A. Tags: Basic Research Source Type: research