Clinical, haematological, and serum biochemical alterations due to spontaneously occurring pulmonary hypertension syndrome in broiler chicken reared under temperate climatic conditions of Northern Himalayas

AbstractThe present study was aimed to investigate the clinical, haematological, and serum biochemical alterations in commercial broiler chickens affected with pulmonary hypertension syndrome. Clinical signs were recorded. Haematological indices were investigated using a MS-4 automatic haem-analyser (MELET Schloesing Laboratories, France). Serum biochemical indices were studied using diagnostic kits (Aspen Laboratories Pvt. Ltd., Rapid Diagnostic Group of Companies, Karnal Road Industrial Area, Delhi, India) and semi-automatic blood chemistry analyser (model SFRI-BSA 3000, Lieu dit Berbanton, France) as per manufacturer ’s literature. The specific clinical signs for pulmonary hypertension syndrome included potbelly with frog sitting posture, gasping, tortuous and distended blood vessels, prolonged bleeding, occasional diarrhoea, and cyanotic comb. Haematological profiling revealed significant increase in haemoglo bin, haematocrit, TEC, MCH, and MCHC; and lymphocytic leukocytosis in clinically ascitic chicken as well as non-ascitic birds from ascitic flocks. Serum biochemical profiling showed significant increase in blood glucose, A:G ratio, serum bilirubin, AST, ALT, LDH, ALP, BUN, and creatinine levels; sig nificant decrease in total protein, albumin, globulin, and HDL cholesterol levels; and non-significant changes in total cholesterol.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research