Acute oral Cannabidiolic Acid Methyl Ester reduces depression-like behavior in two genetic animal models of depression.

CONCLUSION AND IMPLICATIONS: This is the first report of antidepressant efficacy of HU-580. These findings expand the very limited existent results, suggesting that HU-580 is a potent anxiolytic agent. Taken together with its chemical stability, HU-580 emerges as a candidate for a future antidepressant medication. PMID: 29860002 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29860002?dopt=Abstract

Source: Behavioural Brain Research - May 31, 2018 Category: Neurology Authors: Hen-Shoval D, Amar S, Shbiro L, Smoum R, Haj CG, Mechoulam R, Zalsman G, Weller A, Shoval G Tags: Behav Brain Res Source Type: research