Leishmaniasis caused by Leishmania (Viannia) guyanensis in north-central Pacific region of Ecuador: a clinico-epidemiological feature.

Leishmaniasis caused by Leishmania (Viannia) guyanensis in north-central Pacific region of Ecuador: a clinico-epidemiological feature. Acta Trop. 2018 May 28;: Authors: Gomez EA, Kato H, Torres-Romero EX, Velez LN, Villegas NV, Martillo VP, Zambrano FC, Kubo M, Hashiguchi K, Hashiguchi Y Abstract The current four year study was undertaken to investigate the clinical and epidemiological features of Leishmania (Viannia) guyanensis infections in Valle Hermoso, Santo Domingo de Los Tsachilas province, north-central Pacific areas of Ecuador. A total of 155 parasitologically confirmed (Leishmania-amastigote-positive) clinical cases diagnosed at a rural health center during January 2014-December 2017 were analyzed thoroughly. Molecular characterization of the causative Leishmania parasites from different endemic sites within the study areas was performed by PCR amplification of cytochrome b (cyt b) sequencing. All the FTA-card and/or smear impregnated materials tested were characterized, and identified as L. (V.) guyanensis, without detecting any other Leishmania species. The following features were described: 1) the majority of patients were suffered from a single ulcer lesion (simple and mild to chronic), followed by multiple lesions, including recidiva cutis-"like" and Chiclero's ulcer-"like" clinical forms; 2) the majority (65.70%) of lesions were less than 10 mm in size, and distributed mainly on the upper body regions (arm, forearm,...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research