A case report of acute graft-vs-host disease after liver transplantation in a patient presenting with neurogenic symptoms as the single primary manifestation

Acute graft-versus-host disease (aGVHD) is a rare but deadly complication after liver transplantation (LT). It occurs when donor immunocompetent cells transplanted with the liver allograft repopulate and recognize recipient antigens as foreign and mounting an alloreactive response. aGVHD patients can present as skin rash, fever, diarrhea and pancytopenia. These nonspecific symptoms are usually misleading, delaying the diagnosis of aGVHD. Here, we present a patient who developed severe aGVHD after LT, with neurogenic symptoms as the first manifestation.
Source: Transplantation Proceedings - Category: Transplant Surgery Authors: Source Type: research