Request for Proposals: Exploring the Mechanisms for HIV Persistence and the Potential for HIV Eradication

Request for Proposals: Exploring the Mechanisms for HIV Persistence and the Potential for HIV Eradication Deadline: October 15, 2014, 5:00 PM EDT AVAILABLE SUPPORT amfAR, The Foundation for AIDS Research, is pleased to announce the availability of targeted support for biomedical research projects relevant to exploring the mechanisms for HIV persistence and the potential for HIV eradication. Total Cost Maximum: $180,000 Performance Period: February 1, 2015 – January 31, 2017 BACKGROUND AND AREAS OF INTEREST This RFP solicits proposals relevant to exploring the mechanisms for HIV persistence and the potential for HIV eradication. Highly active antiretroviral therapy (HAART) has significantly impacted the health of individuals infected with HIV-1. However, if therapy is interrupted, there is a rapid resumption of viral replication. Understanding the mechanisms by which the virus is able to persist in the face of therapy is necessary in order to identify strategies that may interrupt viral persistence and ultimately lead to viral eradication. amfAR wishes to support basic, pre-clinical, clinical, and especially translational research exploring the mechanisms whereby HIV infection persists; the chronic nature of viral reservoirs and latency; and barriers to the eradication of HIV, with the potential goal of ultimately curing HIV infection. Specific areas of interest fall within the following four categories: Determine the location of persi...
Source: ScanGrants feed - Category: Research Authors: Source Type: funding