Caution, Vigilance, and Personalization: A Must for Any Opioid Conversion
It is with great enthusiasm that we read the letter written by Foxwell and Uritsky in response to our study “The Conversion Ratio from Intravenous Hydromorphone to Oral Opioids in Cancer Patients”.1 Our study concluded after retrospectively reviewing the charts of 394 cancer patients that 1mg of intravenous (IV) hydromorphone is equivalent to 2.5 mg of oral hydromorphone and 11.46 mg of morphine equiv alent daily dose (MEDD). A ratio of 1:2 from IV to oral hydromorphone was recommended in patients receiving high doses of IV hydromorphone.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Akhila Reddy, Yvonne Heung, Eduardo Bruera Source Type: research