The benefits of soluble non-bacterial fraction of kefir on blood pressure and cardiac hypertrophy in hypertensive rats are mediated by an increase in baroreflex sensitivity and decrease in angiotensin-converting enzyme activity

Hypertension is a major risk factor for the development of cardiovascular diseases such as stroke and heart failure. Thus, controlling blood pressure may be crucial to avoiding cardiovascular complications and to decreasing the cost of health services. Blood pressure is physiologically controlled by several mechanisms, including baroreflex [1,2] and the renin-angiotensin system (RAS) [3].The latter is a major drug target used in the management of hypertension [4].

Source: Nutrition - February 7, 2018 Category: Nutrition Authors: Girlandia Alexandre Brasil, Mirian de Almeida Silva-Cutini, Fl ávia de Souza Andrade Moraes, Thiago de Melo Costa Pereira, Elisardo Corral Vasquez, Dominik Lenz, Nazaré Souza Bissoli, Denise Coutinho Endringer, Ewelyne Miranda de Lima, Vinícia Campana Tags: Basic nutritional investigation Source Type: research