LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas

ConclusionOur results confirm the possible role of theLAPTM4B gene in anthracycline resistance in HR − breast cancer. AnalyzingLAPTM4B copy number pattern may support future treatment decision.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research