Clinical and laboratory features of children with community-acquired pneumonia are associated with distinct radiographic presentations

Conclusion: Alveolar CAP, non-alveolar CAP, and clinical CAP are distinct entities differing not only by chest radiographic appearance but also in clinical and laboratory characteristics. Alveolar CAP has unique characteristics, which suggest association with bacterial etiology.Trial registration: Trial number 3075 (Soroka Hospital, Israel)What is Known:• Community-acquired pneumonia in children is diagnosed based on clinical and radiological definitions.• Radiological criteria were standardized by WHO-SICR and have been utilized in vaccine studies.What is New:• Correlation between the WHO-SICR radiological definitions and clinical and laboratory parameters has not been studied.• Using the WHO-SICR radiological definitions for alveolar community-acquired pneumonia (CAP) and non-alveolar CAP and the study definition for clinical CAP, it was found that the groups are distinct, differing clinically and in laboratory parameters.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research