Prevention of ESKAPE pathogen biofilm formation by antimicrobial peptides WLBU2 and LL37

ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species), represent a group of multidrug-resistant (MDR) bacteria that demonstrate the ability to escape antimicrobial treatments. These organisms are highly responsible for nosocomial and community-acquired infections, such as ventilator-associated pneumonia and S. aureus induced diabetic foot infection. Notably, P. aeruginosa contributes directly to the high mortality rate of cystic fibrosis (CF) chronic lung infections.

Source: International Journal of Antimicrobial Agents - May 9, 2018 Category: Drugs & Pharmacology Authors: Qiao Lin, Berthony Deslouches, Ronald C. Montelaro, Y. Peter Di Tags: Short Communication Source Type: research