Safety profile of intraoperative methadone for analgesia after major spine surgery: An observational study of 1,478 patients.

CONCLUSIONS: Mild-moderate respiratory depression is observed following a one-time dose of intraoperative methadone, and monitoring in an appropriate postoperative setting is recommended.
PMID: 29733094 [PubMed - in process]

Source: Journal of Opioid Management - May 9, 2018 Category: Addiction Tags: J Opioid Manag Source Type: research