Hemoglobin A clearance in children with sickle cell anemia on chronic transfusion therapy.

CONCLUSIONS: HbA decline was increased among patients with sickle cell anemia with prior immunologic response to RBC antigens and decreased among those with prior splenectomy, demonstrating that recipient immunologic characteristics influenced the clearance of transfused RBCs. PMID: 29664198 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29664198?dopt=Abstract

Source: Transfusion - April 17, 2018 Category: Hematology Authors: Yee MEM, Josephson CD, Winkler AM, Webb J, Luban NLC, Leong T, Stowell SR, Roback JD, Fasano RM Tags: Transfusion Source Type: research