Effect of Procedure and Coronary Lesion Characteristics on Clinical Outcomes Among Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention: Insights From the PIONEER AF-PCI Trial

Conclusions
Among stented AF patients requiring long-term oral anticoagulation, there was no effect modification by procedure or lesion characteristics of either clinically significant bleeding or major adverse cardiovascular events. Rivaroxaban-based therapy was superior to warfarin plus DAPT in bleeding outcomes regardless of the type of stent or arterial access during the index coronary revascularization. (A Study Exploring Two Strategies of Rivaroxaban [JNJ39039039; BAY-59-7939] and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention [PIONEER AF-PCI]; NCT01830543)

Source: Journal of the American College of Cardiology: Cardiovascular Interventions - April 2, 2018 Category: Cardiology Authors: Kerneis, M., Gibson, C. M., Chi, G., Mehran, R., AlKhalfan, F., Talib, U., Pahlavani, S., Mir, M., Bode, C., Halperin, J. L., Nafee, T., Peterson, E. D., Verheugt, F. W. A., Wildgoose, P., van Eickels, M., Lip, G. Y. H., Fox, K. A. A., Cohen, M. Tags: MOC Source Type: research