Swerchirin exerts anticancer activity on SKOV3 human ovarian cancer cells via induction of mitochondrial apoptosis, G2/M cell cycle arrest and inhibition of Raf/MEK/ERK cascade.

CONCLUSION: In summary, we conclude that swerchirin significantly increased SKOV3 cell death due to cell cycle arrest, loss of MMP, apoptosis and inhibition of Raf/MEK/ ERK pathway. PMID: 29552769 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research