Nigella Sativa: Protecting the Oral Cavity During X-Irradiation in a Mouse Model

Despite advances in radiation delivery, mucositis and xerostomia continue to be debilitating problems for patients undergoing treatment for head and neck cancers. Nigella sativa oil (NSO) is produced from an annual flowering plant that has shown biochemically reproducible and significant cytoprotective properties through anti-inflammatory and anti-oxidant mechanisms when given orally. The goal of this study is to determine whether topical NSO demonstrates radioprotection in oral cavity tissues in mice.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research