In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15.

In conclusion, our data show that Tspan15 and most likely also other members of the TspanC8 family are central modulators of ADAM10-mediated ectodomain shedding in vivo. PMID: 29520422 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29520422?dopt=Abstract

Source: Cellular and Molecular Life Sciences : CMLS - March 8, 2018 Category: Cytology Authors: Seipold L, Altmeppen H, Koudelka T, Tholey A, Kasparek P, Sedlacek R, Schweizer M, Bär J, Mikhaylova M, Glatzel M, Saftig P Tags: Cell Mol Life Sci Source Type: research