NLM Resources: LactMed for Nurses

LactMed, a free database about drugs and lactation, is produced by the National Library of Medicine. It is available via the website, https://toxnet.nlm.nih.gov/newtoxnet/lactmed.htm, or as a mobile app. LactMed provides information on many of the drugs and chemical to which nursing mothers may be exposed, including dietary supplements. The information contained in LactMed includes: Summary statement about use of the drug during lactation; Measurement of levels of the drug in breastmilk; Effects in breastfed infants; Effects on lactation; Alternate drugs to consider. References to research studies are also included with each entry (with links to the citations in PubMed), and all of the data in LactMed is a result of peer-reviewed literature. The database is updated monthly to reflect current research. Records may be downloaded and/or printed for yourself or for your patients. Summary of Use During Lactation: This part of the record offers guidance on the use of the drug or substance during breastfeeding. It summarizes the important points which are provided in the record. If there are conflicting recommendations by experts, the summary mentions all and gives citations to the research. Drug Levels, Maternal and Infant: This section summarizes studies that have measured drug concentrations in breastmilk, and serum or urine concentration in infants. Effects in Infants: Known side effects from the published literature are included here, using an adverse drug reaction assessment m...
Source: Dragonfly - Category: Databases & Libraries Authors: Tags: News from NLM Training & Education Source Type: news

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Inhibition of α-Glucosidase, Intestinal Glucose Absorption, and Antidiabetic Properties by Caralluma europaea. Evid Based Complement Alternat Med. 2018;2018:9589472 Authors: Ouassou H, Zahidi T, Bouknana S, Bouhrim M, Mekhfi H, Ziyyat A, Legssyer A, Aziz M, Bnouham M Abstract Many medicinal plants around the world are used for therapeutic purposes against several diseases, including diabetes mellitus. Due to their composition of natural substances that are effective and do not represent side effects for users, unlike synthetic drugs, in this study, we investigated the inhibitory effect of Carallu...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Muñiz A, Garcia E, Gonzalez D, Zuñiga L Abstract Hyperglycemia in diabetes mellitus causes irreversible life-threatening micro- and macrovascular complications. There is evidence that the glycation reaction leads to a chemical modification of the proteins contributing to the complications of diabetes. It is known that advanced glycation end products (AGEs) are formed by glycation and oxidation reactions called glycoxidation. CML, a nonfluorescent AGE, has become a biomarker of glycoxidative damage; other AGEs appear to induce oxidative stress, which results in cytotoxicity. To determine antio...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Conclusions: It is a common practice for CKI to be integrated with both modern medicines and TCMs when treating CC in China. The associations of medication combinations of CKI in treating CC manifest certain laws for both TCMs and modern medicines. The RWS for validating interrelationships of combined medication may provide evidence for rational use of CKI. Further explorations are needed to verify and expand the conclusions. PMID: 30228827 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Yoo SR, Jeong SJ, Lee MY, Shin HK, Seo CS, Ha H Abstract We had tested antiobesity effect of 52 traditional herbal formulas in 3T3-L1 adipocyte, and Banhasasim-tang (BHSST) was chosen as one of the effective medications to inhibit triglyceride accumulation. We investigated the antiobesity effect of BHSST on 3T3-L1 adipocytes and high-fat diet- (HFD-) induced obese mice. In addition, we evaluated the acute toxicity of BHSST in Sprague Dawley (SD) rats. Differentiated 3T3-L1 cells were treated with various concentrations of BHSST for 8 days. Accumulated triglyceride level and the expressions of adipogenesis-...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Lin YJ, Xu Y, Xu J PMID: 30228825 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
This study aimed to evaluate community pharmacists' knowledge, attitudes, and practices of herbal medicines in the Asir region, Saudi Arabia. Methods: An online cross-sectional study was conducted among 233 community pharmacists using a structured questionnaire. Results: Pharmacists showed considerable knowledge of the indications of herbal products, with an average score of 84% correct answers, total P value
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
(Natural News) Here’s one more reason to start working out — a study has shown that regular exercise can benefit our brain in the long run. The study, a collaborative effort between researchers from Australia’s National Institute of Complementary Medicine at Western Sydney University and the Division of Psychology and Mental Health at the University of...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Authors: Liang W, Li X, Li G, Hu L, Ding S, Kang J, Shen J, Li C, Asakawa T Abstract Background. Erzhi pill (EZP), a traditional Chinese herbal formula, has been widely used to treat postmenopausal osteoporosis (PMOP) in China. However, its molecular mechanisms remain unclear. The aim of the present study is to investigate the antiosteoporotic effect of EZP on an ovariectomized rat model of PMOP. We performed the biomarkers of bone metabolism disorder, bone morphology, bone mineral density (BMD), and bone biomechanics to confirm the successful establishment of the PMOP model. We then investigated the expression of ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Zhao BB, Long QH, Wang CY, Chen LL, Xie GJ, Bo WJ, Xu B, Li ZF, Li HM, Wang P Abstract Introduction. To examine the protective effects of Liu Wei Di Huang Wan formula (LWDH) on liver and orbitofrontal cortex (OFC) injuries in monosodium glutamate (MSG) and partial hepatectomy (PH) rat model. Methods. Neonatal Wistar rats were given MSG or saline on postnatal days 2, 4, 6, 8, and 10. The rats were caged into five groups and treated accordingly at six weeks old as follows: Saline group, Saline+PH group, MSG group, MSG+PH group, and LWDH group (MSG+PH+LWDH). The PH was performed during week 8 by excision of t...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
"Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018": Antihyperglycemic Activity of Hamelia patens Jacq. Extracts. Evid Based Complement Alternat Med. 2018;2018:7926452 Authors: Rugerio-Escalona C, Ordaz-Pichardo C, Becerra-Martinez E, Cruz-López MDC, López-Y-López VE, Mendieta-Moctezuma A, Maldonado-Mendoza IE, Jiménez-Montejo FE Abstract Diabetes is one the world's most widespread diseases, affecting over 327 million people and causing about 300,000 deaths annually. Despite great advances in prevention and thera...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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