Distinct patterns of blood oxygenation in the prefrontal cortex in clinical phenotypes of schizophrenia and bipolar disorder

Schizophrenia (SZ) and bipolar disorder (BD) are characterized by different clinical symptoms, and have previously been considered as categorically separate. However, several lines of evidence controversially suggest that these two disorders may run on a continuum. While it is therefore important to evaluate the subtle differences between SZ and BD, few studies have investigated the difference of brain functioning between the two by focusing on the common symptoms of cognitive functioning and impulsivity, rather than positive/negative and mood symptoms.

Source: Journal of Affective Disorders - February 27, 2018 Category: Neurology Authors: Kazuhiko Yamamuro, Sohei Kimoto, Junzo Iida, Naoko Kishimoto, Shohei Tanaka, Michihiro Toritsuka, Daisuke Ikawa, Yasunori Yamashita, Toyosaku Ota, Manabu Makinodan, Hiroki Yoshino, Toshifumi Kishimoto Tags: Research paper Source Type: research