The miR ‐139‐5p regulates proliferation of supratentorial paediatric low‐grade gliomas by targeting the PI3K/AKT/mTORC1 signalling

ConclusionsThese findings provide the first evidence that down‐regulation of miR‐139‐5p in supratentorial pLGG drives cell proliferation by de‐repressing PI3K/AKT signalling.This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fnan.12479

Source: Neuropathology and Applied Neurobiology - February 1, 2018 Category: Neurology Authors: Giuseppina Catanzaro, Zein Mersini Besharat, Evelina Miele, Martina Chiacchiarini, Agnese Po, Andrea Carai, Carlo Efisio Marras, Manila Antonelli, Manuela Badiali, Alessandro Raso, Samantha Mascelli, Daniel Schrimpf, Damian Stichel, Marco Tartaglia, David Tags: Original Article Source Type: research