Is an Anti-Aging Pill on the Horizon?

Anti-aging products from skin creams to chemical peels are part of a $250 billion industry, but scientists have yet to discover a longevity elixir that stands up to medical scrutiny. A group of researchers believe they’re getting closer, however, thanks to a compound called nicotinamide adenine dinucleotide, or NAD+ for short. “NAD+ is the closest we’ve gotten to a fountain of youth,” says David Sinclair, co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. “It’s one of the most important molecules for life to exist, and without it, you’re dead in 30 seconds.” NAD+ is a molecule found in all living cells and is critical for regulating cellular aging and maintaining proper function of the whole body. Levels of NAD+ in people and animals diminish significantly over time, and researchers have found that re-upping NAD+ in older mice causes them to look and act younger, as well as live longer than expected. In a March 2017 study published in the journal Science, Sinclair and his colleagues put drops of a compound known to raise levels of NAD+ into the water for a group of mice. Within a couple hours, the NAD+ levels in the mice had risen significantly. In about a week, signs of aging in the tissue and muscles of the older mice reversed to the point that researchers could no longer tell the difference between the tissues of a 2-year-old mouse and those of a 4-month-old one. Now scientists are tr...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized anti-aging healthytime Longevity Source Type: news

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RESULTS from studies into the cognitive effects of alcohol hangover have been mixed. They also present methodological challenges, often relying on self-reports of alcohol consumption leading to hangover. The current study measured Breath Alcohol Concentrat...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
This study evaluated PHYLLPRO™, a standardized ethanol extract of P. amarus leaves for protection against oxidative stress and recovery from hangover symptoms. MATERIAL AND METHODS: Ten days daily oral supplementation of 750 mg/day followed by intoxication was evaluated in a randomized placebo-controlled (containing only excipient), crossover study in 15 subjects (21-50 years old), for oxidative stress, liver damage, alleviating hangover symptoms (Hangover Severity Score: HSS) and mood improvement (Profile-of-Mood-Scores: POMS). RESULTS: PHYLLPRO™ was able to remove blood alcohol in the ac...
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
AIM: To review current alcohol hangover research in animals and humans and evaluate key evidence for contributing biological factors. METHOD: Narrative review with alcohol hangover defined as the state the day after a single episode of heavy drinki...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Professor David Nutt, based in London, and colleagues have been creating 'alcosynth' for years. It targets parts of the brain that make consumers feel tipsy but not nauseous.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Scientist David Nutt memorably said alcohol is more dangerous than crack. Now, he is trying to invent a healthy synthetic alternative, and the race is on to get it to market‘This is what my brain looks like,” says David Nutt, showing me an intense abstract painting by a friend of his that is sitting on the windowsill in his office. Nutt’s base at Hammersmith hospital has a cosy, lived-in feel – a stark contrast to the gleaming white laboratory he oversees as di rector of the neuropsychopharmacology unit at Imperial College London. Lab coats hang on a hook by the door, an ancient kettle sits in the c...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: David Nutt Food & drink industry Alcohol Life and style Alcoholism Science Source Type: news
In this study, we reviewed the relationship between the inducing diuresis effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS.
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
The Rugby player admitted his hangover cure is a day on the sofa, broccoli and some coconut water. He revealed he's keen on lager tops, 'nothing too wild'.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
The symptoms of a hangover can also be caused by medical treatments and conditions, but without any of the temporary pleasure gained from our favourite tipple. Here, we explain why.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Reuters Health) - The old adage that drinking beer before wine prevents hangovers turns out to be a myth, German researchers say.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
ConclusionsCertain risk behaviors can identify young men with a high risk of developing severe liver disease. Wine consumption was not associated with a reduced risk for severe liver disease compared to beer and spirits.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
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