Involvement of PI3K, Akt, and RhoA in oestradiol regulation of cardiac iNOS expression.

CONCLUSION: Our results suggest that oestradiol in vivo regulates cardiac iNOS expression via the PI3K/Akt signaling pathway, through attenuation of RhoA and AT1R. PMID: 29437011 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29437011?dopt=Abstract

Source: Current Vascular Pharmacology - February 12, 2018 Category: Drugs & Pharmacology Authors: Zafirovic S, Sudar-Milovanovic E, Obradovic M, Djordjevic J, Jasnic N, Borovic ML, Isenovic ER Tags: Curr Vasc Pharmacol Source Type: research