Clinical pathologic case report: A 70-year-old man with inflammatory cerebral amyloid angiopathy causing headache, cognitive impairment, and aphasia

Publication date: March 2018 Source:Journal of Clinical Neuroscience, Volume 49 Author(s): Grace F. Crotty, Kathleen McKee, Altaf Saadi, Andrew C. Young, Isaac H. Solomon, Jennifer L. Lyons A 70-year-old man presented with two months of worsening cognitive impairment, hallucinations, and difficulty speaking, with superimposed headaches. Cerebrospinal fluid analysis was notable for lymphocytic pleocytosis and elevated protein. Imaging studies revealed multiple acute and subacute infarcts with cortical microhemorrhages. The patient underwent a stereotactic brain biopsy. In this article, we discuss the patient’s differential diagnosis, pathologic findings, ultimate diagnosis, and clinical outcome.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research