Lipoprotein-associated phospholipase A ₂ activity is increased in patients with definite familial hypercholesterolemia compared with other forms of hypercholesterolemia

Lipoprotein-associated phospholipase A2 (Lp-PLA2) plays a key role in atherosclerosis development. It is considered a marker of increased risk of cardiovascular disease (CVD) and plaque vulnerability. Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated plasma levels of low-density lipoprotein cholesterol and a higher prevalence of early CVD.

http://www.nmcd-journal.com/article/S0939-4753(18)30047-4/fulltext?rss=yes

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 1, 2018 Category: Nutrition Authors: Alessandro Mattina, David Rosenbaum, Randa Bittar, Dominique Bonnefont-Rousselot, Davide Noto, Maurizio Averna, Eric Bruckert, Philippe Giral Source Type: research