Phenotypic differences of amyotrophic lateral sclerosis (ALS) in China and Germany

ConclusionsThe apparent discrepancies between German and Chinese ALS patients (age at onset, gender distribution, bulbar forms, cognitive dysfunction, risk factors) reveal a quite different clinical phenotype in China, maybe due to socioeconomic status, environmental factors or genetic background. The observed differences in phenotype need to be pursued by further epidemiological studies on environmental and genetic risk factors.
Source: Journal of Neurology - Category: Neurology Source Type: research