p16, p21, and p53 proteins play an important role in development of pancreatic intraepithelial neoplastic

Conclusionsp16, p21, and p53 proteins play an important role in the deregulation of the cell cycle and participate in the development of pancreatic intraepithelial neoplasia. Immunohistochemical evaluation of their expressions may be helpful in the diagnosis of PanIN.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research