Simultaneous detection of single ‐nucleotide variant, deletion/insertion, and fusion in lung and thyroid carcinoma using cytology specimen and an RNA‐based next‐generation sequencing assay

CONCLUSIONSCytology preparations can be a reliable source for the detection of both DNA and RNA aberrations. The ability to simultaneously detect multiple types of genomic variants is crucial for patients with advanced cancer and maximizes the usefulness of cytology specimens. Cancer Cytopathol 2018. © 2018 American Cancer Society.

Source: Cancer Cytopathology - January 1, 2018 Category: Pathology Authors: Natalya V. Guseva, Omar Jaber, Aaron A. Stence, Krishnaveni Sompallae, Amani Bashir, Ramakrishna Sompallae, Aaron D. Bossler, Chris S. Jensen, Deqin Ma Tags: Original Article Source Type: research