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Oral prednisolone versus non-steroidal anti-inflammatory drugs in the treatment of acute gout: a meta-analysis of randomized controlled trials

ConclusionsOral prednisolone may be of similar efficacy and a slightly safer strategy for treatment of active, acute gout compared with NSAIDs. Further clinical studies are still warranted to investigate its long-term efficacy and safety.
Source: Inflammopharmacology - Category: Drugs & Pharmacology Source Type: research

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Authors: Deschamps R, Stankoff B, Vignal C, Benoist JF, Wolf B, Gout O PMID: 29778138 [PubMed - in process]
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
BACK pain can occur in the lower or upper areas of the back. Treatment for the condition includes stretching and taking medications to relieve the symptoms. Making this treat could help reduce your symptoms.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
A 3-year-old female presented with 4 months of recurrent fevers, abdominal pain, hematuria, and proteinuria with negative urine cultures. On examination, she was hypertensive with bruises over her left cheek. Labs were remarkable for serum creatinine 0.78 mg/dl (estimated glomerular filtration rate of 48.3 ml/min per 1.73 m2 using the revised Schwartz formula); hemoglobin 8.5 gm/dl; hematocrit 27.9%; platelet 92 × 103/ul; urinalysis with 11–20 red blood cells/high-power field; spot urine protein/creatinine ratio 1.97 mg/mg; low haptoglobin; elevated lactate dehydrogenase; and schistocytes on peripheral smear.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Image Source Type: research
This commentary summarizes the revised evidence-based Guidelines on the Assessment of Pain in Older Adults which have been developed by the British Pain Society and British Geriatrics Society.Age and Ageing
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
More than 300 people have taken the manufacturers of allegedly faulty hip replacements to the High Court.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
Discussion Leg pain in children has a broad differential diagnosis and includes more innocuous problems such as growing pains and transient synovitis but also more serious problems including neurological diseases or malignancy. Occult or self-limited trauma are also common causes. A review can be found here. Limping can be painful or painless and has its own differential diagnosis which can overlap with leg pain. A differential diagnosis for limping can be found here. Muscle weakness also has its’ own differential diagnosis which can be found here. Learning Point Benign acute childhood myositis (BACM) has other names...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Possibly one of the most hotly discussed aspects of clinical reasoning and pain relates to thoughts and beliefs held by both people experiencing pain and the clinicians who work with them. It’s difficult to avoid reading papers about “pain education”, “catastrophising”, “maladaptive thinking”, but quite another to find a deeper analysis of when and why it might be useful to help people think differently about their pain, or to deal with their thoughts about their experience in a different way. Cognition is defined by the APA Dictionary of Psychology as 1. all forms of knowing and ...
Source: HealthSkills Weblog - Category: Anesthesiology Authors: Tags: Assessment Chronic pain Clinical reasoning Cognitive skills Pain conditions Science in practice biopsychosocial Health healthcare Therapeutic approaches treatment Source Type: blogs
AbstractUnresponsive wakefulness syndrome is a disorder of consciousness wherein a patient is awake, but completely non-responsive at the bedside. However, research has shown that a minority of these patients remain aware, and can demonstrate their awareness via functional neuroimaging; these patients are referred to as having ‘cognitive motor dissociation’ (CMD). Unfortunately, we have little insight into the subjective experiences of these patients, making it difficult to determine how best to promote their well-being. In this paper, I argue that the capacity to experience pain or pleasure (sentience) is a ke...
Source: Neuroethics - Category: Medical Ethics Source Type: research
Publication date: Available online 20 May 2018 Source:The Veterinary Journal Author(s): Andrew Bell The mechanisms by which noxious stimuli produce the sensation of pain in animals are complex. Noxious stimuli are transduced at the periphery and transmitted to the CNS, where this information is subject to considerable modulation. Finally, the information is projected to the brain where it is perceived as pain. Additionally, plasticity can develop in the pain pathway and hyperalgesia and allodynia may develop through sensitisation both peripherally and centrally. A large number of different ion channels, receptors, and cel...
Source: The Veterinary Journal - Category: Veterinary Research Source Type: research
Publication date: Available online 19 May 2018 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Solène Duros, Krystel Nyangoh Timoh
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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