PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord

ConclusionOur findings demonstrate that inhibiting PKM2 expression effectively attenuates CCI-induced neuropathic pain and inflammatory responses in rats, possibly through regulating ERK and STAT3 signaling pathway.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research