Hepatitis B immunoglobulin-induced hypercoagulability complicating liver transplantation necessitating ECMO, rescue hepatectomy, and retransplantation

With the patient's written informed consent, we describe the course of a 55-year-old Asian male with hepatitis B cirrhosis (+HBsAg, MELD 25), hepatocellular carcinoma (HCC) status post ablation, and chronic kidney disease (non-dialysis dependent) undergoing split liver and kidney transplant from the same deceased donor. We administered hepatitis B immunoglobulin after hepatectomy. After renal reperfusion, the graft became mottled and was explanted with hyperacute rejection suspected. The hepatic graft appeared viable.
Source: Journal of Clinical Anesthesia - Category: Anesthesiology Authors: Tags: Correspondence Source Type: research