Clinic characteristics and neurodegenerative risk in idiopathic REM sleep behavior disorder: study in 58 patients

Introduction: REM sleep behaviour disorder (RBD) is a REM parasomnia characterized by abnormal behaviours emerging during REM sleep in relation with unpleasant dreams. RBD can be classified as idiopathic (IRBD) when neurological disease, relevant motor or cognitive complaints do no exist, or secondary when it is associated with a neurological disorder the introduction of certain drugs or alcohol withdrawal. RBD can precede the onset of the motor or cognitive symptoms by several years and longitudinal studies have shown that most of patients diagnosed with IRBD develop the motor and cognitive features of a neurodegenerative disease, particularly the synucleinopathies as Parkinson disease (PD), Lewy bodies dementia (LBD), or multiple system atrophy (MSA).
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: REM Behavior Disorders Source Type: research