Heritability of Atrial Fibrillation [Original Articles]

Conclusions— Genetic variation contributes substantially to AF risk. The risk for AF conferred by genomic variation is similar to that observed for several other cardiovascular diseases. Established AF loci only explain a moderate proportion of disease risk, suggesting that further genetic discovery, with an emphasis on common variation, is warranted to understand the causal genetic basis of AF.

http://circgenetics.ahajournals.org/cgi/content/short/10/6/e001838?rss=1

Source: Circulation: Cardiovascular Genetics - December 13, 2017 Category: Cardiology Authors: Weng, L.-C., Choi, S. H., Klarin, D., Smith, J. G., Loh, P.-R., Chaffin, M., Roselli, C., Hulme, O. L., Lunetta, K. L., Dupuis, J., Benjamin, E. J., Newton-Cheh, C., Kathiresan, S., Ellinor, P. T., Lubitz, S. A. Tags: Arrhythmias, Atrial Fibrillation, Epidemiology, Genetic, Association Studies, Genetics Original Articles Source Type: research