Lung RNA-sequencing to understand the heterogeneity of COPD

Conclusions: Severe airflow limitation represents a distinctive transcriptomic signature in comparison to mild COPD and non-smokers. Transcriptomic changes of mild former smokers with COPD vs. non-smokers are more heterogeneous.Supported, in part, Instituto de Salud Carlos III (PI15/00799), CP (16/00039) and a grant from MSD.

http://erj.ersjournals.com/cgi/content/short/50/suppl_61/PA969?rss=1

Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Faner Canet, M. R., Fernandez, G., Cruz, T., Lopez-Giraldo, A., Molins, L., Kalko, S., Agusti, A. Tags: Molecular Pathology and Functional Genomics Source Type: research