Underestimation of bronchial obstruction in patients with coronary heart disease and cardiac insufficiency

Aim: To study the effect of bronchial obstruction on clinical features and treatment effectiveness in patients with coronary heart disease (CHD) with cardiac insufficiency in persons, exposed to ionizing radiation. The study included 72 patients with CHD, exposed to ionizing radiation, who were admitted to hospital for cardial insufficiency. Conducted physical examination, chest x-ray, spirometry, echocardiography, electrocardiogram, clinical blood tests, evaluation of dyspnea scale MMRC, BMI.Results: Patients with cardial insufficiency 43 (59.7 %) revealed different degrees of (II-III) obstructive or mixed (obstructive-restrictive) changes in spirometry. In 29 (67,5 %) patients COPD was diagnosed for the first time, 14 patients with previously diagnosed COPD were not receiving adequate basic therapy. Patients with comorbidity were older, had greater body mass index, smoked longer and more intensely. All patients received the traditional therapy for cardiac insufficiency, which included ß-blokers, combined diuretic therapy, glycosides, ACE inhibitors. The mean initial level of FEV1 was (1,37±0,4 l), FVC – (2.35±0,4) l (58,59%) and VC of 2.64±0.5 l, (64,97%). The use of adequate basic therapy of COPD with LABA or LAMA resulted in improvement of respiratory function (significant increase of FEV1, FVC, VC), significant and persistent reduction of swelling without changing of diuretic therapy, improvement of increase in ejection fraction, decrease...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Others Source Type: research