Locally advanced squamous cell cervical cancer in a patient with septate uterus.
Locally advanced squamous cell cervical cancer in a patient with septate uterus. J Contemp Brachytherapy. 2017 Oct;9(5):487-489 Authors: Yavas G, Yavas C, Inan G Abstract A 33-year-old premenopausal multiparous woman with the history of septate uterus was referred to the hospital with menorrhagia and inter-menstrual bleeding occurring for the last 6 months. Work-up revealed a stage IIB cervical cancer. The patient underwent curative chemo/radiotherapy. The patient's septate uterus presented several difficulties during application. Brachytherapy was applied using standard computed tomography-compatible tandem and ovoids. The high-risk clinical target volume (HR-CTV), intermediate risk CTV, and organs at risk were contoured according to the Groupe Européen de Curiethérapie - European Society for Radiology and Oncology (GEC-ESTRO) guidelines. Treatment was performed via 3-dimensional high-dose-rate technique with 192Ir, with brachytherapy dose of 28 Gy in 4 fractions/7 Gy each, prescribed to the HR-CTV. Treatment was well tolerated with manageable acute toxicities. To the best of our knowledge, the current case is the second case of septate uterus with locally advanced cervical carcinoma. Due to the lack of guidelines about brachytherapy applications in patients with uterine anomaly and owing to the anatomical anomaly, brachytherapy application is challenging in this patients population. PMID: 29204170 [PubMed]
Conclusion: The TNFA -308 AG genotype is associated with a decreased risk of aneurysm or hemorrhagic stroke in a population from the capital of Brazil, Distrito Federal.RESUMO Introdu ção: Muitas doenças cerebrovasculares relacionam-se com processos inflamatórios, portanto, a influência de vários polimorfismos em doenças tem sido estudada para melhorar o conhecimento sobre os mecanismos fisiológicos do sistema nervoso. Objetivo: Identificar a associação entre um polimo rfismo na posição -308 do gene TNFA e o desenvolvimento de acidente vascu...
Officially it ’s a ‘unique holiday hotel for cancer patients and those with life-threatening illnesses’, according to the sign outside the Twenties green-shuttered building in Bournemouth.
Sarah Brookes, 41, a mother of two from Bradford, West Yorkshire, would like commercial sunbeds to be banned outright.
Abstract The aim of this study was to evaluate the influence of a novel ultrasonic tip as an auxiliary method for removing filling material from flattened/oval-shaped canals. The null hypothesis tested was that this method does not influence removing the filling material in flattened/oval-shaped canals. Forty-five mandibular incisors were selected and randomly divided into three experimental groups (n = 15) according to different protocols for removing root canal filling material. Group R: Reciproc R25/.08, Group RC: Reciproc R25/.08 + Clearsonic tip, and Group CR: Clearsonic tip + Reciproc R25/.08. The teeth were scanned ...
ConclusionsIn a setting of short waiting list times, IABP can be used to bridge candidates to urgent HT with acceptable postoperative results, but there were significant rates of adverse clinical events during support.ResumenIntroducción y objetivosEn España, el balón de contrapulsación intraaórtico (BCIA) se ha usado frecuentemente como puente al trasplante cardiaco (TxC) urgente. El propósito es analizar los resultados de esta estrategia.MétodosSe realizó una revisión retrospectiva caso por caso de los registros clínicos de 281 pacientes adultos listad...
Publication date: August 2018Source: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Volume 1870, Issue 1Author(s): Chi Van Dang
Publication date: August 2018Source: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Volume 1870, Issue 1Author(s):
The steep increase in thyroid cancer diagnosis has not been mirrored by increasing mortality rates and is likely due to widespread overdiagnosis of small neoplasms.
The presence of HER3 expression and a high HER2/CEP17 ratio distinguish a group of invasive HER2-positive ductal breast cancer patients who have a worse prognosis.
Publication date: 13 August 2018Source: Cancer Cell, Volume 34, Issue 2Author(s): Manisha Rao, Scott PowersIn this issue of Cancer Cell, Menghi et al. show that tandem duplications (TDs) are a common genetic feature of gynecological and triple-negative breast cancers. They also provide evidence that these TDs generate genetic alterations driving these cancers, which, if substantiated, will fundamentally change our understanding of their oncogenesis.