Locally advanced squamous cell cervical cancer in a patient with septate uterus.
Locally advanced squamous cell cervical cancer in a patient with septate uterus. J Contemp Brachytherapy. 2017 Oct;9(5):487-489 Authors: Yavas G, Yavas C, Inan G Abstract A 33-year-old premenopausal multiparous woman with the history of septate uterus was referred to the hospital with menorrhagia and inter-menstrual bleeding occurring for the last 6 months. Work-up revealed a stage IIB cervical cancer. The patient underwent curative chemo/radiotherapy. The patient's septate uterus presented several difficulties during application. Brachytherapy was applied using standard computed tomography-compatible tandem and ovoids. The high-risk clinical target volume (HR-CTV), intermediate risk CTV, and organs at risk were contoured according to the Groupe Européen de Curiethérapie - European Society for Radiology and Oncology (GEC-ESTRO) guidelines. Treatment was performed via 3-dimensional high-dose-rate technique with 192Ir, with brachytherapy dose of 28 Gy in 4 fractions/7 Gy each, prescribed to the HR-CTV. Treatment was well tolerated with manageable acute toxicities. To the best of our knowledge, the current case is the second case of septate uterus with locally advanced cervical carcinoma. Due to the lack of guidelines about brachytherapy applications in patients with uterine anomaly and owing to the anatomical anomaly, brachytherapy application is challenging in this patients population. PMID: 29204170 [PubMed]
Earlier in the day, McCain's daughter, Meghan, tearfully interviewed former Vice President Joe Biden, whose son Beau died from the same cancer, glioblastoma
A new type of ultrasound scan is being tested to see if it's as effective as mammograms in detecting breast cancer, especially in women with dense breast tissue. CBS News' Danielle Nottingham reports.
Authors: Copur MS, Wurdeman JM, Nelson D, Ramaekers R, Gauchan D, Crockett D Abstract Solid tumors involving glandular organs express mucin glycoprotein which is eventually shed into the circulation. As aresult these proteins can easily be measured in the serum and be used as potential tumor markers. The most commonly used tumor markers for breast cancer are CA 27-29 and CA 15-3, which both measure the glycoprotein product of the mucin-1 (MUC1) gene. CA 27-29 has been approved by the US Food and Drug Administration for monitoring disease activity in breast cancer patients. Most oncology clinical practice guidelines...
CONCLUSIONS: Radical radiotherapy is effective and well-tolerated in NSCLC patients with postoperative locoregional recurrence. High BED is a predictor for long LRFS, and the presence of wild-type EGFR is a predictor for long DMFS. PMID: 29228994 [PubMed - in process]
If proven to be effective, the new type of scans could eventually be used in addition to annual mammograms
An arrest warrant has been issued for a New York couple who fraudulently pocketed thousands of dollars in donations for a 5-year-old boy with cancer and then missed a court sentencing
Authors: Omi Y, Horiuchi K, Haniu K, Tokura M, Nagai E, Isozaki O, Nagashima Y, Okamoto T Abstract Primary hyperparathyroidism is the most common hormonal manifestation associated with multiple endocrine neoplasia 1 (MEN1). It is generally caused by parathyroid hyperplasia, and parathyroid carcinoma is rare. Here, we report a case of MEN1 with parathyroid carcinoma in two parathyroid glands causing primary hyperparathyroidism. A 40-year-old man with primary hyperparathyroidism due to MEN1 underwent a total parathyroidectomy. His corrected calcium and intact PTH (i-PTH) serum levels were 10.8 mg/dL and 203 pg/mL, re...
The common spice, found in many Indian dishes, has properties that can help fight cancer and inflammation, researchers say.
(Reuters Health) - Patients who survive head and neck cancer may be more likely to experience declines in cognitive function than people who don ’t have these tumors, a recent study suggests.
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