Acute and late toxicities in localized prostate cancer patients treated with low-dose 125I brachytherapy (110 Gy) in combination with external beam radiation therapy versus brachytherapy alone (160 Gy).
Conclusions: To our knowledge, this is the first report to compare the GU and gastrointestinal toxicities between the combination therapy and BT monotherapy (160 Gy) for localized prostate cancer. Unexpectedly, there were more late GU toxicities (except for hematuria) in the BT monotherapy group. PMID: 30479615 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Predicting pubic arch interference in permanent prostate brachytherapy based on the specific parameters derived from nuclear magnetic resonance imaging.
Conclusions: This new method derived from MRI has predictive value, as AoPAI, hPAI, hPAIMax, and AoPAIMax could predict PAI. Taking other factors into consideration, we suggest the use of AoPAI as a novel and very reliable predictor of PAI. PMID: 30479616 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The analysis of the long-term outcomes in elderly women treated for locally advanced cervical cancer.
Authors: Koper K, Dziobek K, Makarewicz R, Terlikiewicz J, Dutsch-Wicherek M Abstract Purpose: Locally advanced cervical cancer (LACC) should be treated with a combination of external irradiation and brachytherapy with concurrent chemotherapy. However, as cervical carcinoma cells can disperse by way of the lymphatic system to either pelvic or para-aortic nodes, planning the extent of radiation requires precise information about the spread of the disease to the lymph nodes, especially to the para-aortic area. Material and methods: All of the 75 women included in our study underwent chemoradiotherapy, which start...
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of impact of target delineation of computed tomography- and magnetic resonance imaging-guided brachytherapy on dose distribution in cervical cancer.
Conclusions: A combination of MRI and CT is a safe alternative approach for cervical cancer HDR brachytherapy. The technique provides comparable dosimetric outcomes to MRI-based planning, while being more cost-effective. PMID: 30479618 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate interstitial brachytherapy in recurrent head and neck cancer: an effective salvage option.
We present our results in patients with recurrent head and neck cancers treated with HDR interstitial brachytherapy. Material and methods: Twenty-five patients with recurrent head and neck cancers were treated with HDR interstitial brachytherapy using Iridium 192 between 2009 and 2016. Of these, 75% received radical brachytherapy, and 25% received external beam radiation therapy (EBRT) followed by brachytherapy boost. Treatment sites included oral cavity (15/25) and oropharynx (10/25). Median dose of 4.5 Gy was administered twice per day, with median total brachytherapy dose of 40.5 Gy in radical and 27 Gy for EBRT cas...
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Interstitial brachytherapy in soft tissue sarcoma: a 5 years institutional experience with Cobalt 60-based high-dose-rate brachytherapy system.
Conclusions: Combination of surgery and ISBT with/out EBRT improves local and distant control with acceptable late toxicities. 60Co-based ISBT is safe and gives a good outcome. PMID: 30479620 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image-guided interstitial high-dose-rate brachytherapy in the treatment of metastatic esophageal squamous cell carcinoma.
Conclusions: Image-guided IBT is a safe and effective treatment in patients with metastasized esophageal squamous cell carcinoma. PMID: 30479621 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single fraction computed tomography-guided high-dose-rate brachytherapy or stereotactic body radiotherapy for primary and metastatic lung tumors?
Conclusions: Brachytherapy plans showed significant higher GTV mean dose compared to MB- and RO-SBRT (122.2 Gy vs. 50.4 and 44.7 Gy, p
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A systematic review of treating recurrent head and neck cancer: a reintroduction of brachytherapy with or without surgery.
Conclusions: Although surgery remains a mainstay treatment for RHNC, intraoperative interstitial brachytherapy delivery as adjunctive therapy may improve the treatment outcome and may be associated with fewer complication rates as compared to reirradiation using external beam radiotherapy. Further investigations are required to elucidate the role of brachytherapy for RHNC. PMID: 30479623 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Experimental study of pelvic perioperative brachytherapy with iodine 125 seeds (I-125) in an animal model.
Conclusions: These results show the technical feasibility of the pelvic mesh implantation in ewes. A phase I study for patients with locally advanced or recurrent pelvic tumors amenable to surgery, in combination with surgical resection should be possible. PMID: 30479624 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Inversely designed, 3D-printed personalized template-guided interstitial brachytherapy for vaginal tumors.
Conclusions: 3D-printed templates designed using medical images are useful, especially for ISBT of vaginal tumors. Further verification of clinical indications, design of templates, and manufacturing process are needed. PMID: 30479625 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

An automated dose verification software for brachytherapy.
Conclusions: With minimal human-computer interactions, the DVS can verify the accuracy of doses calculated by the TPS. PMID: 30479626 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Transitional cell carcinoma of endometrium: a case report of rare pure form.
Authors: Cuccia F, Mortellaro G, Spera A, Evangelista G, Casto AL, Ferrera G Abstract Transitional cell carcinoma is a very rare histological subtype of endometrial cancer, with only 18 cases described in literature. Ovary represents the most common site where it accounts for 2% of all ovarian cancers. Due to the rarity of this disease, current management is controversial and includes various approaches, mostly described in the adjuvant setting, both radiotherapy and chemotherapy alone or in combination. Here, we report a case of a 65-year-old patient who underwent adjuvant vaginal brachytherapy for an endometrial ...
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dose coverage comparison between "interstitial catheter-only" and "hybrid intracavitary-interstitial brachytherapy" for early stage squamous cell carcinoma of the buccal mucosa.
Conclusions: The HBT approach appears to enable improved dose coverage of irregular-shaped enoral tumor volumes compared to ISBT-only for patients with early stage BSCC. PMID: 30479628 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 28, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Pre-implant magnetic resonance and transrectal ultrasound imaging in high-dose-rate prostate brachytherapy: comparison of prostate volumes, craniocaudal extents, and contours.
Authors: Grisotto S, Cerrotta A, Pappalardi B, Carrara M, Messina A, Tenconi C, Valdagni R, Fallai C Abstract Purpose: The purpose of this study was to compare the prostate contours drawn by two radiation oncologists and one radiologist on magnetic resonance (MR) and transrectal ultrasound (TRUS) images. TRUS intra- and inter-fraction variability as well as TRUS vs. MR inter-modality and inter-operator variability were studied. Material and methods: Thirty patients affected by localized prostate cancer and treated with interstitial high-dose-rate (HDR) prostate brachytherapy at the National Cancer Institute in ...
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Plan reproducibility of intraoperatively custom-built linked seeds compared to loose seeds for prostate brachytherapy.
This study aimed to evaluate and compare plan reproducibility of intraoperatively built custom linked seeds and loose seeds for prostate brachytherapy. Material and methods: Between December 2010 and March 2014, 76 localized prostate cancer patients received Iodine-125 brachytherapy with external beam radiotherapy. Linked and loose seeds were implanted in 39 and 37 patients, respectively. The primary endpoint was the mean (± standard deviation) of the absolute change in the minimum dose received by 90% of the prostate volume between intraoperative and post-operative planning (ΔD90) to confirm plan reproduc...
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Five-year effectiveness of low-dose-rate brachytherapy: comparisons with nomogram predictions in patients with non-metastatic prostate cancer presenting significant control of intra- and periprostatic disease.
Authors: Zimmermann JS, Osieka R, Bruns T, Hollberg H, Wiechmann B, Netzbandt O, Sablotny J, Malade M, Heitz M, Bernhardt F, Tiemann J, Wilkens M, Brüske T, Welker U, Heinemann V, Zimmermann P, de la Maza SF, Pfeiffer D, Tauber PR, Thomas D, Moustakis C Abstract Purpose: To assess the effectiveness of low-dose-rate (LDR) brachytherapy in patients with localized prostate cancer and to compare the outcome with predictions from Kattan and Partin nomograms at 60 months after seed implantation. Material and methods: One thousand, one hundred and eighty-seven patients with localized prostate cancer at low-, inte...
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Development and preclinical testing of a novel biodegradable hydrogel vaginal packing technology for gynecologic high-dose-rate brachytherapy.
Conclusions: The novel strategy for polyethylene glycol (PEG)-based hydrogel intra-vaginal packing was able to rapidly polymerize in human cadavers with minimal heat production. Delivery was efficient and able to fill the contours of the vaginal cavity and displace tissue away from the applicator axis. The hydrogel has favorable imaging characteristics on CT and MRI, and shows a potential for clinical use, warranting additional studies for the use in humans. PMID: 30237814 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

EROS study: evaluation between high-dose-rate and low-dose-rate vaginal interventional radiotherapy (brachytherapy) in terms of overall survival and rate of stenosis.
Conclusions: In our analysis, there were no differences in terms of OS and late toxicity outcomes for patients receiving LDR or HDR VBT. HDR VBT is a safe technique in comparison to LDR VBT. PMID: 30237815 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Clinical and dosimetric consequences of imperfect applicator insertion in cervical cancer brachytherapy.
This study analyzes clinical consequences and dosimetric variations after imperfect brachytherapy insertions. It examines treatment decisions after such insertions in patients having difficult anatomy, which leads to good subsequent insertions with acceptable dose volume parameters. Material and methods: We reviewed images of all insertions performed during last one year and sorted faulty ones out. Clinical outcome was assessed, analyzing original treatment records. Repeat three-dimensional planning using identical dose-optimization-technique compared their dosimetry. Statistical analysis using SPSS®-Statistics-sof...
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Radiobiological doses, tumor, and treatment features influence on local control, enucleation rates, and survival after epiescleral brachytherapy. A 20-year retrospective analysis from a single-institution: part I.
Conclusions: The results show as predictive factors of local control, enucleation, and disease-specific survival rates those related with the features of the tumor, specifically the longest basal dimension. There is no clear relation between radiobiological doses or treatment parameters in patients after brachytherapy. PMID: 30237817 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Radiobiological doses, tumor, and treatment features influence on outcomes after epiescleral brachytherapy. A 20-year retrospective analysis from a single-institution: part II.
Conclusions: Tumor factors in addition to radiation treatment may contribute to secondary effects. Enhanced clinical optimization should evaluate radiobiological doses delivered to the tumor volume and surrounding normal ocular structures. PMID: 30237818 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of clinical efficacy and complications of 125I seed brachytherapy and stereotactic body radiation therapy for recurrent pulmonary metastases from colorectal carcinoma.
Authors: Li J, Zhang L, Xie Q, Wang W, Hua Y, Sun Z Abstract Purpose: To evaluate the efficacies of 125I seed implantation and stereotactic body radiation therapy (SBRT) in treatment of recurrent lung metastases from colorectal cancer, to compare the tolerance of lung tissue to both forms of radiotherapy, and to analyze the factors that affect the prognosis. Material and methods: According to treatment received, thirty colorectal cancer patients with post-operative lung metastases were separated into two groups: 125I seed implantation group (group A; n = 16) and SBRT group (group B; n = 14). Patients were follo...
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Effectiveness and safety of a robot-assisted 3D personalized template in 125I seed brachytherapy of thoracoabdominal tumors.
Conclusions: Through analysis of the selected patients with thoracoabdominal tumors, the robot-assisted 3D personalized template in 125I seed brachytherapy was a more effective and safer method. It can achieve a more favorable OS and LC. PMID: 30237820 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate brachytherapy in severe trismus: Making it happen!
We present a report on the management of a previously-irradiated completely edentulous patient with severe trismus for whom high-dose-rate surface mould brachytherapy had been prescribed. A unique, reliable, and practical solution has been presented based firmly on the scientific knowledge of contemporary implant dentistry. PMID: 30237821 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Official Annual Meeting of Indian Brachytherapy Society8th ANNUAL CONFERENCE OF INDIAN BRACHYTHERAPY SOCIETY 2018 (IBSCON 2018) PROCEEDINGS.
Authors: Mummudi N, Gudi S, Bhalavat R, Mahantshetty U, Indian Brachytherapy Society PMID: 30237822 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 22, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The Tumor Boards - is this strategy worth for developing countries?
Authors: Pellizzon ACA PMID: 30038637 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy.
Authors: Chapman CH, Braunstein SE, Pouliot J, Noworolski SM, Weinberg V, Cunha A, Kurhanewicz J, Gottschalk AR, Roach MI, Hsu IC Abstract Purpose: Radiation dose escalation for prostate cancer improves biochemical control but is limited by toxicity. Magnetic resonance spectroscopic imaging (MRSI) can define dominant intraprostatic lesions (DIL). This phase I study evaluated dose escalation to MRSI-defined DIL using high-dose-rate (HDR) brachytherapy. Material and methods: Enrollment was closed early due to low accrual. Ten patients with prostate cancer (T2a-3b, Gleason 6-9, PSA
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric evaluation of Point A and volume-based high-dose-rate plans: a single institution study on adaptive brachytherapy planning for cervical cancer.
Conclusions: Our study reports the relative improvement in OAR doses per HDR-BT fraction by HDRVOL planning compared to HDRPointA planning and demonstrates the dosimetric advantages of volume-based HDR-BT planning in creating more conformal plans. PMID: 30038639 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Hypofractionated external beam radiation therapy in combination with HDR boost for localized prostate cancer: patient reported quality of life outcomes.
Conclusions: Our study suggests HypoF EBRT can be delivered in combination with HDR for patients with ntermediate-risk and high-risk adenocarcinoma of the prostate without increasing toxicity compared to SF with an HDR boost. PMID: 30038640 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Initial experience using superflab as intravaginal packing during interstitial brachytherapy for advanced gynecologic cancer.
We report our experience using superflab bolus as vaginal packing to displace OAR during interstitial brachytherapy. Material and methods: Twelve patients with stage IB-IVA gynecologic cancer were treated with definitive chemoradiation including interstitial brachytherapy. A Syed template was used for a computed tomography (CT)-based pre-plan with magnetic resonance imaging (MRI) fusion. A 1-2 cm superflab bolus was cut and sterilized. The tandem and obturator were placed, and superflab was then inserted into the vagina. Interstitial needles were then placed through the template and superflab as per the pre-plan under ...
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparative study of concomitant chemoradiation versus concomitant chemoradiation followed by high-dose-rate intraluminal brachytherapy in locally advanced esophageal carcinoma: a single institutional study.
Conclusions: In our study, addition of brachytherapy as a boost following concurrent chemoradiation failed to improve treatment outcomes without additional toxicity in locally advanced esophageal cancer. PMID: 30038642 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Quality assurance during interstitial brachytherapy: in vivo dosimetry using MOSFET dosimeters.
Conclusions: The deviations between planned and measured dose values were markedly influenced by the proximity of the detector to the PTV because where the edema exerts, the greatest influence on the tube applicator geometry. The positioning of the patient during irradiation must correspond to the positioning in the planning CT. Further studies are needed to investigate the role of in vivo dosimetry during interstitial brachytherapy as a routine procedure. PMID: 30038643 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

UK & Ireland Prostate Brachytherapy Practice Survey 2014-2016.
UK & Ireland Prostate Brachytherapy Practice Survey 2014-2016. J Contemp Brachytherapy. 2018 Jun;10(3):238-245 Authors: Corey G, Yoosuf ABM, Workman G, Byrne M, Mitchell DM, Jain S Abstract Purpose: To document the current prostate brachytherapy practice across the UK and Ireland and compare with previously published audit results. Material and methods: Participants from 25 centers attending the annual UK & Ireland Prostate Brachytherapy Conference were invited to complete an online survey. Sixty-three questions assessed the center's experience and staffing, clinician's experience, clinical...
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy boost after chemoradiation in anal cancer: a systematic review.
Authors: Frakulli R, Buwenge M, Cammelli S, Macchia G, Farina E, Arcelli A, Ferioli M, Fuccio L, Tagliaferri L, Galuppi A, Frezza GP, Morganti AG Abstract Radio-chemotherapy (RCT) is the primary treatment of anal cancer (AC). However, the role and the optimal total dose of a radiation boost is still unclear. No randomized controlled trials nor systematic reviews have been performed to analyze the efficacy of brachytherapy (BRT) as boost in AC. Therefore, we performed this systematic review based on PRISMA methodology to establish the role of BRT boost in AC. A systematic search of the bibliographic databases: PubMe...
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A national survey of AIRO (Italian Association of Radiation Oncology) brachytherapy (Interventional Radiotherapy) study group.
Conclusions: This survey illustrates the current status of brachytherapy in Italy and should encourage collaboration to develop, implement, and monitor its use when appropriate. PMID: 30038646 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

ENT COBRA ONTOLOGY: the covariates classification system proposed by the Head & Neck and Skin GEC-ESTRO Working Group for interdisciplinary standardized data collection in head and neck patient cohorts treated with interventional radiotherapy (brachytherapy).
Conclusions: The COBRA Ontology is a good response to the multi-dimensional criticalities of data collection, retrieval, and usability. It allows to create a software for large multicentric databases with implementation of specific remapping functions wherever necessary. This approach is well-received by all involved parties, primarily because it does not change a single center's storing technologies, procedures, and habits. PMID: 30038647 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image-guided high-dose-rate interstitial brachytherapy technique for locally recurrent rectal cancer in perineum.
Conclusions: Image-guided HDR interstitial brachytherapy in selected patient with LRRC in perineum is a proven, effective, and safe treatment method with relatively long-term outcome. PMID: 30038648 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Case report of a dose-volume histogram analysis of rib fracture after accelerated partial breast irradiation: interim analysis of a Japanese prospective multi-institutional feasibility study.
Authors: Yoshida K, Otani Y, Nose T, Yoden E, Asahi S, Tsukiyama I, Dokiya T, Saeki T, Fukuda I, Sekine H, Kumazaki Y, Takahashi T, Kotsuma T, Masuda N, Nakashima K, Matsumura T, Nakagawa S, Tachiiri S, Moriguchi Y, Itami J, Oguchi M Abstract We initiated the first multi-institutional prospective study of accelerated partial breast irradiation for early breast cancer in Japan. Our early clinical results showed that the treatment methods were technically reproducible between institutions and showed excellent disease control at a median follow-up of 26 months in our previous report. At present, total 46 patients from...
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image-guided high-dose-rate intracavitary brachytherapy technique for nasal keloid - a case report.
In conclusion, HDR intracavitary brachytherapy is an effective way to prevent the recurrence of nasal keloids post-surgery. PMID: 30038650 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 26, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Ruthenium brachytherapy for intraocular growth of a conjunctival squamous cell carcinoma: a case report.
Authors: Rospond-Kubiak I, Adamski W, Sosnowska K, Kociȩcki J, Marszałek A Abstract The aim of this study is to report the use of ruthenium brachytherapy as an adjunctive treatment in the management of an intraocular extension of the conjunctival squamous cell carcinoma (SCC). In 2013, a 73-year-old man presented with a tumor blocking the angle and infiltrating corneal endothelium. The patient was treated with iridectomy, and after one month, ruthenium brachytherapy was applied. 4.5 years post-irradiation, the treated eye is painless, and no recurrence was noted. We advocate the use of ruthenium brachytherapy as ...
Source: Journal of Contemporary Brachytherapy - May 29, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Advantages of intraoperative implant for interstitial brachytherapy for accelerated partial breast irradiation either frail patients with early-stage disease or in locally recurrent breast cancer.
Conclusions: This technique, although time-consuming, achieves good local disease control with a satisfactory toxicity profile in both early-stage and local recurrent breast cancer patients. It may be especially suitable for frail patients. PMID: 29789758 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Combined external beam radiotherapy and vaginal brachytherapy versus vaginal brachytherapy in stage I, intermediate- and high-risk cases of endometrium carcinoma.
Conclusions: VBT alone is as effective as EBRT+VBT in ensuring loco-regional control and achieving comparable survival rates, with fewer toxic effects for patients with stage I intermediate- and high-risk endometrial carcinoma. The dose escalation did not make a difference in the survival rates and was like in the other major trials (PORTEC-2). PMID: 29789759 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate brachytherapy in treatment of non-melanoma skin cancer of head and neck region: preliminary results of a prospective single institution study.
Conclusions: With appropriate patient selection and choosing as lowest dose per fraction as possible, HDR brachytherapy with customized surface molds yields good oncological and cosmetic results for the treatment of localized skin BCC and SCC. PMID: 29789760 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Visual outcome after posterior uveal melanoma episcleral brachytherapy including radiobiological doses.
Conclusions: Visual acuity changes can be modeled by an exponential function for the first 5 years after treatment. No relation between VA loss and BED has been found; nevertheless, apical height, plaque size, juxtapapillary localization, and dose to fovea were found as statistical significant variables. PMID: 29789761 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Percutaneous computed tomography-guided permanent 125I implantation as therapy for pulmonary metastasis.
Authors: Huo X, Huo B, Wang H, Wang L, Cao Q, Zheng G, Wang J, Chai S, Zhang Z, Yang K, Niu Y, Wang H Abstract Purpose: To evaluate intermediate-term outcomes after computed tomography (CT)-guided radioactive 125I seed implantation (CTRISI), and to determine prognostic variables associated with outcomes in patients with pulmonary metastases. Material and methods: Thoracic surgeons evaluated and performed implantation of 125I radioactive seeds under CT guidance or combined with surgical resection. Patients were monitored in the thoracic surgery clinic for recurrence and survival. Results: Fifty patients (31 ...
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Verification of high-dose-rate brachytherapy treatment planning dose distribution using liquid-filled ionization chamber array.
Conclusion: The dosimetric properties of IA 2.5-5 mm showed the applicability of liquid-filled ionization chamber array as a potential QA device for HDR brachytherapy treatment planning systems. PMID: 29789763 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A single institution analysis of low-dose-rate brachytherapy: 5-year reported survival and late toxicity outcomes.
Conclusions: LDR brachytherapy is an effective treatment option in low- to intermediate-risk prostate cancer patients. We observed low biochemical relapse rates and minimal GU toxicities several years after treatment in patients with or without TURP. However, a small risk of urinary retention was observed in some patients. PMID: 29789764 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Successful salvage treatment of refractory recurrence of maxillary sinus carcinoma using image-guided high-dose-rate interstitial brachytherapy.
Authors: Zhang Y, Wu N, Zhao Z, Chen Q, Cheng G Abstract This case report illustrates a treatment effect of image-guided high-dose-rate (HDR) interstitial brachytherapy for refractory recurrence of maxillary sinus carcinoma. A 61-year-old male was previously admitted to another hospital and received surgery because of left maxillary sinus squamous cell carcinoma (SCC) 6 years ago. Tumor regrowth was noted 2 years after the initial radical surgery. The patient accepted local excision again for the recurrence, followed by external beam radiotherapy. Despite salvage treatment with surgery and external irradiation...
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Salvage high-dose-rate brachytherapy for prostate cancer persistence after brachytherapy: repeated use of a polyethylene glycol hydrogel spacer.
Conclusions: The use of a hydrogel prior to salvage HDR-BT in a patient previously treated with HDR-BT is feasible and could help reduce the rectal exposure in the salvage setting. PMID: 29789766 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 27, 2018 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research