SKIN-COBRA (Consortium for Brachytherapy data Analysis) ontology: The first step towards interdisciplinary standardized data collection for personalized oncology in skin cancer.
Conclusions: Large databases are natural extension of traditional statistical approaches, a valuable and increasingly necessary tool for modern healthcare system. Future analysis of the collected multinational and multicenter data will show whether the use of the system can produce high-quality evidence to support multidisciplinary management of non-melanoma skin cancer and utilizing this information for personalized treatment decisions. PMID: 32395133 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer.
Authors: Gursel SB, Serarslan A, Meydan AD, Okumus N, Yasayacak T Abstract Purpose: The standard treatment for locally advanced stage cervical cancer is definitive radiotherapy, the quality of which affects both survival and side effects. Brachytherapy is a major component of definitive radiotherapy; it is administered using different techniques and applicators. The purpose of this study was to dosimetrically compare tandem ovoid (T-ovoid) and tandem ring (T-ring) brachytherapy treatments. Material and methods: Both applicator sets were applied to the same 20 patients, and treatment plans were made three-dimens...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Prolonged treatment planning can increase real rectal dose in 3D brachytherapy for cervical cancer.
Conclusions: Extended treatment planning time for brachytherapy due to the changes in topography of small pelvis can lead to different dose in high-risk organs than previously planned. It seems that the most significant changes are related to rectum. PMID: 32395135 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients.
Conclusions: Exclusive short course adjuvant VBT is an effective treatment in patients with early-stage endometrial cancer and provides good outcomes in terms of disease local control and DFS, with low rates of toxicity profile. PMID: 32395136 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Multimodality treatment in unresectable cholangiocarcinoma.
Conclusions: Multimodality therapeutic approach in patients with inoperable ECCs could definitely improve their survival time and decrease complications. Survival time is significantly depending on tumor staging, gender, and involvement of liver parenchyma, great vessels, and regional lymph nodes. PMID: 32395137 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Inter-observer and intra-observer variability in reporting vaginal dose points for cervical cancer in high-dose-rate brachytherapy.
Conclusions: There is a need to ensure consistency in vaginal points reporting. The impact of the dosimetric inter- and intra-observer variability should also be considered when dealing with dose tolerances and limits due to the potential dose gradient. PMID: 32395138 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Verification of needle guidance accuracy in pelvic phantom using registered ultrasound and MRI images for intracavitary/interstitial gynecologic brachytherapy.
Conclusions: In this study, we showed that under ideal conditions, rigid registration between MRI images and US images obtained high accuracy for real-time image guidance. Additionally, registered US images provided accurate image guidance during visual needle insertion in IC/IS gynecologic brachytherapy to achieve a combination of effective visualization and image guidance. PMID: 32395139 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Coverage with dosimetric concordance index (CDCI): a tool for evaluating dosimetric impact of inter-observer target variability in brachytherapy.
Authors: Upreti RR, Budrukkar A, Upreti U, Wadasadawala T, Pathak R, Misra S, Gurrum L, Kinhikar RA, Deshpande DD Abstract Purpose: The aim of this study was to propose an index for evaluating dosimetric impact of inter-observer target delineation variability in brachytherapy. Material and methods: The coverage with dosimetric concordance index (CDCI) is expressed as CDCIcommon and CDCIpair. The CDCIcommon is the mean coverage of target volume with common volume irradiated by prescription dose among all observers and represents the condition of worst target coverage. CDCIpair is the generalized form of CDCI, wh...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Does inverse planning improve plan quality in interstitial high-dose-rate breast brachytherapy?
Authors: Major T, Fröhlich G, Mészáros N, Smanykó V, Polgár C Abstract Purpose: To investigate the effect of input parameters for an inverse optimization algorithm, and dosimetrically evaluate and compare clinical treatment plans made by inverse and forward planning in high-dose-rate interstitial breast implants. Material and methods: By using a representative breast implant, input parameters responsible for target coverage and dose homogeneity were changed step-by-step, and their optimal values were determined. Then, effects of parameters on dosimetry of normal tissue and organ...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature.
Conclusions: Combined primary vaginal cancer and POP is an extremely rare clinical entity, with only a few cases reported in the literature. When applying CRT in these cases, critical organ doses may be higher than expected due to the downward descent of the pelvic organs. Especially in elderly patients, a pessary can be used as a non-surgical procedure to restore the anatomy for symptom relief during definitive CRT. Additionally, it allows tumors to be targeted more precisely. PMID: 32395142 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Interstitial high-dose-rate brachytherapy as a boost in synchronous prostate and rectal cancer treatment: case report and literature review.
Authors: Konat-Bąska K, Chicheł A, Staszek-Szewczyk U, Maciejczyk A, Matkowski R Abstract Purpose: Prostate and colorectal cancers are the first and the third most popular malignancies in male population, in which some patients may develop these tumors metachronously or synchronously. At present, there are no standard recommendations, and oncologists need to provide an optimal management for two different cancers with an acceptable risk of possible treatment of adverse effects. Material and methods: This case report presents the treatment of a 61-year-old patient suffering from synchronous prostate and rectal...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Small bowel perforation caused by applicator implantation in high-dose-rate interstitial brachytherapy for recurrent pelvic tumor: a case report.
We describe a case of small bowel perforation caused by applicator implantation in an 82-year-old male patient with recurrence tumor in the pelvis treated with HDR-ISBT. Eventually, the patient underwent laparotomy and partial intestinal resection. We recognized the site where the applicator was inserted into a part of the tumor on the mucosal surface. Pathological examination confirmed that the tumor had infiltrated the small intestine directly and that the infiltrated part had reached the submucosa. This is the first published report about small bowel perforation caused by applicator implantation. In cases where intestin...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A radiobiological study of the schemes with a low number of fractions in high-dose-rate brachytherapy as monotherapy for prostate cancer.
Conclusions: The α/β obtained in our analysis of 22.8 Gy for a range of dose per fraction between 6 and 20.5 Gy was much greater than the one currently estimated for prostate cancer using low doses per fraction. This high value of α/β explains reasonably well the data available in the region of high doses per fraction considered. PMID: 32395145 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evaluation of rectal volume correlation with dosimetric parameters during optimized intracavitary high-dose-rate brachytherapy in cervical cancer.
This study aimed to evaluate the rectal volume and dose-volume histogram (DVH) relationship in high-dose-rate (HDR) brachytherapy in locally advanced cervical cancer. Material and methods: Planning computed tomography of 65 patients who underwent HDR brachytherapy boost as a component of definitive radiotherapy from March 2016 to February 2018 were reviewed. OARs and target volume were re-delineated by a single physician to decrease interobserver variation. Two sets of plan were generated; in the first set, the dose was prescribed to point A with Manchester system loading pattern, while in the second set, the dose was ...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 32395147 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Public health measures, radiotherapy, and the novel coronavirus outbreak.
Authors: Pellizzon ACA PMID: 32395148 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A history of transurethral resection of the prostate should not be a contra-indication for low-dose-rate 125I prostate brachytherapy: results of a prospective Uro-GEC phase-II trial.
Conclusions: The excellent long-term results and low morbidity presented as well as many advantages of prostate brachytherapy over other treatments demonstrates that brachytherapy is an effective treatment for patients with transurethral resection and organ-confined prostate cancer. PMID: 32190063 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Clinical outcomes of low-dose-rate brachytherapy based radiotherapy for intermediate risk prostate cancer.
Conclusions: This study highlights excellent outcomes for intermediate-risk prostate cancer patients, including unfavorable intermediate-risk cases, treated with BED ≥ 200 Gy radiotherapy using LDR brachytherapy. LDR alone with a BED of 200 Gy may be an optimal treatment for both favorable and unfavorable intermediate-risk prostate cancer patients, although a longer follow-up is mandatory to confirm the present findings. PMID: 32190064 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The value of hybrid interstitial tandem and ring applicators for organ at risk dose reduction in small volume cervical cancer.
Authors: Crossley N, Tipton C, Meier T, Sudhoff M, Kharofa J Abstract Purpose: Magnetic resonance imaging (MRI)-guided adaptive brachytherapy is the standard of care for cervical cancer. Hybrid intracavitary/interstitial applicators for bulky tumor (high-risk clinical target volume [HR-CTV]> 30 cc) dose escalation is recommended in the EMBRACE II trial. The value of hybrid applicators for smaller HR-CTV (
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

3D printer-based novel intensity-modulated vaginal brachytherapy applicator: feasibility study.
Conclusions: The novel brachytherapy applicator met the necessary requirements in quality control tests. PMID: 32190066 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evaluation of a new bi-valve vaginal speculum applicator design for gynecologic interstitial brachytherapy.
Conclusions: Our speculum applicator can reproduce a conventional pear-shaped dose distribution. Our current clinical practice will use this applicator, which can improve the patient's treatment results. PMID: 32190067 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric comparison of two different applicators and rectal retraction methods used in inverse optimization-based intracavitary brachytherapy for cervical cancer.
Authors: Biltekin F, Gultekin M, Yilmaz MT, Yildiz F Abstract Purpose: The purpose of this study was to evaluate the dosimetric differences between two different applicators and rectal-retraction methods used in image-guided brachytherapy (IGBT) for locally advanced cervical cancer (LACC). Material and methods: Ten patients with LACC treated with definitive chemoradiotherapy and inverse optimization-based IGBT were included in this study. In each patient, at least one fraction of IGBT was performed using tandem-ovoids (TO) with vaginal gauze packing (VGP) or tandem-ring (TR) with rectal-retractor (RR). High-ris...
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The Medanta AOLO template for locally advanced cancer cervix brachytherapy: design and clinical implementation.
Conclusions: We have developed an easy to use IC + IS type of template/applicator, which was successfully implemented in our clinical practice. PMID: 32190069 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Combined interstitial and surface high-dose-rate brachytherapy treatment of squamous cell carcinoma of the hand.
Conclusions: The first interstitial and surface HDR brachytherapy for cutaneous squamous cell carcinoma of a finger interspace for hand function preservation is presented. The initial experience revealed that brachytherapy was tolerated but with notable acute and late side effects. Treatment did result in tumor shrinkage with organ preservation and function of two rays. A larger cohort of patients will be required for additional conclusions related to long-term clinical benefits in patients who refuse ray amputation. PMID: 32190070 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

First experience of 192Ir source stuck event during high-dose-rate brachytherapy in Japan.
Authors: Kumagai S, Arai N, Takata T, Kon D, Saitoh T, Oba H, Furui S, Kotoku J, Shiraishi K Abstract Purpose: To share the experience of an iridium-192 (192Ir) source stuck event during high-dose-rate (HDR) brachytherapy for cervical cancer. Material and methods: In 2014, we experienced the first source stuck event in Japan when treating cervical cancer with HDR brachytherapy. The cause of the event was a loose screw in the treatment device that interfered with the gear reeling the source. This event had minimal clinical effects on the patient and staff; however, after the event, we created a normal treatment ...
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The role of vaginal brachytherapy in stage I endometrial serous cancer: a systematic review.
Conclusions: These data support the concept that in adequately selected patients, VBT alone may be a suitable radiotherapy technique in women with stage I USC who underwent surgical staging and received adjuvant chemotherapy. PMID: 32190072 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The role of brachytherapy in the management of brain metastases: a systematic review.
Conclusions: For a variety of reasons including absence of physician expertise in brachytherapy, lack of published data on treatment outcomes, and rates of radiation necrosis, brachytherapy is not presently a part of standard paradigm for brain metastases. However, our review indicates brachytherapy as a modality that offers excellent local control and quality of life, and suggested that its use should be further studied. PMID: 32190073 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Can brachytherapy be properly considered in the clinical practice? Trilogy project: The vision of the AIRO (Italian Association of Radiotherapy and Clinical Oncology) Interventional Radiotherapy study group.
Conclusions: The AIRO vision implies that specific strategic interventions must be carried out in the field of national guidelines, education, research, and communication with patients and colleagues of other specialties in an interdisciplinary setting. PMID: 32190074 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

NORTH EUROPE BRACHYTHERAPY USERS MEETING: 10-11 October, 2019Park Inn by Radisson, London Heathrow.
Authors: PMID: 32190075 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 32190076 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 31969906 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Maria Sk łodowska-Curie - the first lady of nuclear physics.
Maria Skłodowska-Curie - the first lady of nuclear physics. J Contemp Brachytherapy. 2019 Dec;11(6):505-509 Authors: Pospieszny T PMID: 31969907 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

HAPPY - Humanity Assurance Protocol in interventional radiotheraPY (brachytherapy) - an AIRO Interventional Radiotherapy Study Group project.
Conclusions: The aim of the present paper was to produce a protocol consisting in intervention that could improve the internal serendipity and emotional state of patients who underwent HDR-IRT. PMID: 31969908 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High precision radiotherapy including intensity-modulated radiation therapy and pulsed-dose-rate brachytherapy for cervical cancer: a retrospective monoinstitutional study.
Conclusions: Our study confirms that the combination of IMRT and PDR-BT can be considered an effective treatment for cervical cancer, ensuring high local control, despite the high percentage of locally advanced disease. PMID: 31969909 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Patterns of cervical cancer brachytherapy in India: results of an online survey supported by the Indian Brachytherapy Society.
Conclusions: Our survey suggested a fairly uniform treatment paradigm for cervical cancer brachytherapy, with a progressive shift from 2D to 3D image-based parameters for planning, with persistence of point A based prescription. Further efforts are needed to augment and ease this transition. PMID: 31969910 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Reducing dysphagia with palliative 2D high-dose-rate brachytherapy improves survival in esophageal cancer.
Authors: Burchardt W, Chyrek A, Burchardt E, Bielęda G, Trojanowski M, Chicheł A Abstract Purpose: The goal of this study was to assess the effectiveness of dysphagia relief and overall survival in patients with advanced esophageal cancer treated with palliative high-dose-rate (HDR) brachytherapy (BT) without computed tomography-based planning. Material and methods: Palliative 2D HDR-BT was used to treat 93 patients with advanced or incurable esophageal cancer in a regional cancer center from October 2010 to December 2016. Before the treatment patients presented the following grades of dysphagia: 0 - 0%, I - ...
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Detection of individual prostate cancer via multiparametric magnetic resonance imaging in own material - initial experience.
Conclusions: Introducing pre-biopsy mpMRI into our contemporary PCa diagnosis pathway increased the diagnostic yield of transrectal biopsy by increasing the prostate cancer detection. This enabled the introduction of clinically significant prostate cancer (csPCa) treatment. mpMRI application also allowed biopsy to be avoided among patients with no csPCa. PMID: 31969912 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A dosimetric study of electron beam therapy vs. high-dose-rate mould brachytherapy in adjuvant treatment of non-melanoma skin carcinomas of the head and neck region.
Conclusions: CT-based surface mould brachytherapy results in better conformity of superficial lesions on small, irregular surfaces such as the nose and inner canthus than electrons with a slightly higher skin dose. PMID: 31969913 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Analysis of local recurrence causes in uveal melanoma patients treated with 125I brachytherapy - a single institution study.
Authors: Kowal J, Markiewicz A, Dębicka-Kumela M, Bogdali A, Jakubowska B, Karska-Basta I, Romanowska-Dixon B Abstract Purpose: To perform a retrospective analysis of factors which might affect the occurrence of a relapse of uveal melanoma after 125I brachytherapy. Material and methods: The analysis concerned 343 patients treated in the years 2001-2012. The effect on local recurrence of such factors as patient's sex, age, tumour size, shape, pigmentation, location, presence of orange pigment or petechiae on tumour surface, retinal detachment, and blood or dispersed pigment in vitreous body were studied. Additi...
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Measurements and Monte Carlo calculation of radial dose and anisotropy functions of BEBIG 60Co high-dose-rate brachytherapy source in a bounded water phantom.
Conclusions: In this study, we validated the egs_brachy calculation of the TG43U1 dataset for the BEBIG 60Co source for an unbounded geometry. Subsequently, we measured the g(r) and F(r,θ) for the same source using an in-house water phantom. In addition, we validated these experimental results with the values calculated using the egs_brachy MC code, with the same geometry and similar phantom material as used in the experimental methods. PMID: 31969915 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A new implant device to prevent edema-associated underdosage in high-dose-rate interstitial brachytherapy of mobile tongue cancer.
Conclusions: The described silicone device has the potential to prevent underdosage to the treatment target related to tongue edema. It has been shown to be safe and easy to implement. PMID: 31969916 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Endovascular brachytherapy for extensive right-heart and pulmonary artery sarcoma - a case report.
Conclusions: Endovascular brachytherapy is a novel, safe and effective therapeutic modality for non-resectable primary cardiac sarcomas either for palliation of obstruction, or tumor mass reduction to allow complete resection. PMID: 31969917 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric effects of the Smit sleeve on high-dose-rate brachytherapy tandem and ovoids plans for patients with locally advanced cervical cancer.
Authors: Mehta S, Farnia B, de la Zerda A, Rahimi R, Wolfson A, Portelance L Abstract Purpose: Smit sleeves are used to facilitate insertion of the intrauterine tandem during brachytherapy for cervical cancer. When a tandem and ovoids system is used the base of the Smit sleeve displaces the ovoids distally. The dosimetric impact of this displacement is not known. Herein we performed a dosimetric analysis to quantify this impact on the integral dose and dose delivered to the organs at risk (OARs). Material and methods: Eleven high-dose-rate brachytherapy plans in which a Smit sleeve was used with a tandem and ov...
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Critical review of multidisciplinary non-surgical local interventional ablation techniques in primary or secondary liver malignancies.
Authors: Kovács A, Iezzi R, Cellini F, Lancellotta V, Bischoff P, Carchesio F, Tagliaferri L, Kovács G, Gambacorta MA Abstract Local non-surgical interventional percutaneous ablation represents nowadays an important part of the potential treatment strategies. Although surgical ablation represents the gold standard, in the past decade there was an expansion in the use of non-surgical ablative techniques: radiofrequency, microwave, laser, cryoablation, irreversible electroporation, and interventional radiotherapy (brachytherapy) in primary as well as secondary liver cancers. With the growing experience ...
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Prostate brachytherapy procedural training: incorporation of related procedures in resident training and competency assessment.
Authors: Bachand J, Schroeder SR, Desai NB, Folkert MR Abstract Purpose: Inadequate procedural training is of increasing concern in resident training, especially in prostate brachytherapy (PB). Transperineal rectal spacer placement (TRSP) requires many of the same proficiencies as PB. This work describes the assessment of teaching techniques focusing on developing critical competencies for PB using related clinical procedures (TRSP). Material and methods: For PB and TRSP, key competencies were identified: 9 for PB and 7 for TRSP; 4 are shared between PB and TRSP. "Comfort level" with these procedures ...
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 31749845 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 22, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Polish Brachytherapy Society - Presidential opening: Chasing Brachytherapy.
Authors: Wojcieszek P PMID: 31749846 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 22, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single fraction high-dose-rate brachytherapy as monotherapy for low and intermediate risk prostate cancer: toxicities and early outcomes from a single institutional experience.
Authors: Barnes JM, Gabani P, Sanders M, Chundury A, Altman M, Garcia-Ramirez J, Li H, Zoberi JE, Baumann BC, Gay HA Abstract Purpose: High-dose-rate brachytherapy (HDR-BT) delivered in a single fraction as monotherapy is a potential treatment modality for low- and intermediate-risk prostate cancer (LIR-PC); however, outcome data with this technique remain limited. Here we describe our institutional HDR monotherapy experience and report the efficacy and toxicity of this treatment. Material and methods: LIR-PC patients who received a definitive single fraction HDR-BT during 2013-2017 were retrospectively identif...
Source: Journal of Contemporary Brachytherapy - November 22, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Analysis of quality of life after randomized controlled trial of alpha-1 adrenoceptor antagonist alone and in combination with cyclooxygenase-2 inhibitor in patients who underwent low-dose-rate brachytherapy for prostate cancer.
Conclusions: Combination treatment with celecoxib and tamsulosin during the peri-operative period is not warranted for improving QoL in patients undergoing LDR brachytherapy. PMID: 31749848 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 22, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Results from chemoradiotherapy for squamous cell cervical cancer with or without intracavitary brachytherapy.
Conclusions: BT-IC boost was associated with a lower recurrence rate and better overall survival and recurrence-free survival. EBRT boost patients had a three-fold increase in the risk of recurrence. Brachytherapy is essential in the treatment of cervical cancer and improved alternatives are needed for patients who are not candidates for standard brachytherapy applicators. PMID: 31749849 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - November 22, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research