High-dose-rate Brachytherapy as Adjuvant Local rEirradiation for Salvage Treatment of Recurrent breAst cancer (BALESTRA): a retrospective mono-institutional study.
Conclusions: Our preliminary analysis showed that HDR-BT is a feasible treatment for partial breast reirradiation offering very low complications rate and fast procedure. Higher patients' cohort is warranted in order to define the role of this treatment modality in the breast conservative management of local recurrence. PMID: 32695191 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Patient and physician reported toxicity with two-fraction definitive high-dose-rate prostate brachytherapy: the impact of implant interval.
Conclusions: HDR brachytherapy for prostate cancer is a well-tolerated treatment. The interval between treatments is not associated with differences in patient-reported QOL or physician-graded toxicities. PMID: 32695192 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The efficacy of the combination of percutaneous transhepatic biliary drainage and 125I stranded seeds for malignant bile duct obstruction treatment.
Authors: Li S, Li B, Li L, Yang X, Xu F, Wang W Abstract Purpose: To investigate the efficacy of percutaneous transhepatic biliary drainage (PTBD) combined with iodine-125 (125I) stranded seeds for the treatment of malignant bile duct obstruction (MBO). Material and methods: A retrospective study was performed on 58 consecutive MBO patients. Twenty patients underwent PTBD combined with 125I stranded seeds (group A). Thirty-eight patients underwent percutaneous trans-hepatic biliary drainage (group B). Total bilirubin, direct bilirubin, and indirect bilirubin levels were compared preoperatively, 1-week, 1-month,...
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Iodine-125 seed implantation for residual hepatocellular carcinoma or cholangiocellular carcinoma in challenging locations after transcatheter arterial chemoembolization: Initial experience and findings.
Conclusions: CT-guided ISI for HCC or CCC lesions in challenging locations after TACE is both highly effective and safe. PMID: 32695194 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate brachytherapy of primary cutaneous B-cell lymphoma: the first reported case series.
Conclusions: HDR-BT allows for achieving high local control of CBCLs with relatively low-late toxicity in the form of skin discoloration in most patients. PMID: 32695195 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric evaluation of vaginal cuff brachytherapy planning in cervical and endometrial cancer patients.
Conclusions: VCB planning with the use of CT is essential. CT can facilitate the selection of optimal cylinder size to reduce the occurrence of large AGs. A few percent of plans require correction of dose distribution because of hot spots in OARs and the presence of AGs. Enema before cylinder insertion does not influence rectosigmoid Dmax and D2cm3. The analysis revealed no bladder volume effect on bladder doses Dmax and D2cm3. PMID: 32695196 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Analysis of clinical utilization of ring applicator for combined intracavitary/interstitial image-guided brachytherapy treatment in Chinese patients with locally advanced cervical cancer.
Authors: Zhao Z, Zhang N, Liu Y, Wu N, Mao Z, Yang W, Cheng G Abstract Purpose: To analyze the results of clinical utilization of ring applicator for combined intracavitary (IC)/interstitial (IS) image-guided brachytherapy (BT) technique in locally advanced cervical cancer (LACC), and to explore the application conditions of IC/IS BT approach with this applicator for Chinese patients. Material and methods: IC/IS BT was performed in total of 95 LACC patients, who already received external beam radiotherapy. In forty-three of these patients, utilization of ring applicator in brachytherapy was done, including IC/I...
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Biological dose summation of intensity-modulated arc therapy and image-guided high-dose-rate interstitial brachytherapy in intermediate- and high-risk prostate cancer.
Conclusions: Based on our biological dose summation method, the total dose of prostate is higher using BT boost than the IMAT. BT boost yields lower rectum, bladder, and hips doses, but higher dose to urethra. UDC overestimates rectum and bladder dose and underestimates the dose to urethra. PMID: 32695198 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single-fraction low-energy electronic brachytherapy for conjunctival lymphoma.
Conclusions: Single dose kilovoltage brachytherapy was effective and safe in this small cohort of patients. Based on the literature, there is an evidence that local treatment in short-course radiotherapy is effective and should be considered amongst therapeutic options for these patients; however, this novel approach should be evaluated prospectively in a larger cohort. PMID: 32695199 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy.
Conclusions: Our palliative treatment technique appears to be safe, effective, and less invasive, and could be a treatment option for symptomatic patients with head and neck cancer. PMID: 32695200 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of initial computed tomography-based target delineation and subsequent magnetic resonance imaging-based target delineation for cervical cancer brachytherapy.
Conclusions: The use of asynchronous MRI for target delineation, with co-registration to CT for each fraction of brachytherapy was associated with higher D90 to the HR-CTV. We observed slightly higher D2cc rectal doses with MRI, but cumulative rectal doses were within accepted thresholds. High-risk target volumes were not consistently increased or decreased, but MRI fusion was associated with target volume changes greater than 20% in over half of the treated patients. PMID: 32695201 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The 100 most cited articles in prostate cancer brachytherapy: systematic review and bibliometric analysis.
Conclusions: The bibliometric analysis presents a detailed list of the 100 most cited articles in prostate cancer brachytherapy. There are clear recommendations for treatment with prostate cancer brachytherapy. The goal of prostate cancer brachytherapy is to improve long-term outcomes and quality of life. PMID: 32695202 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy in cervical cancer radiotherapy during COVID-19 pandemic crisis: problems and prospects.
This article presents in detail the issues and possible solutions with currently available literature for COVID-19 and radiation, in particular brachytherapy management of locally advanced cervical cancers. The review attempts to provide possible explanations and pathways based on COVID-19 testing, brachytherapy processes including application, imaging, and fractionation, keeping in mind the overall treatment time. PMID: 32695203 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image-guided interstitial brachytherapy boost for nasopharyngeal carcinoma: technical aspects.
Authors: Murakami N, Cheng G, Yoshimoto S, Itami J Abstract Nasopharyngeal cancer generally responds well to concurrent chemoradiotherapy (CCRT). However, there is a small group of patients who respond poorly to CCRT, and experience local residual tumor or local relapse. Although several attempts have been performed to such a group of patients including re-irradiation with external beam radiation therapy (EBRT) or salvage surgery, clinical results remain unsatisfactory. Intracavitary brachytherapy (ICBT) boost after CCRT with EBRT has been explored, however, its efficacy is limited to those with superficial residua...
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 32695205 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

SKIN-COBRA (Consortium for Brachytherapy data Analysis) ontology: The first step towards interdisciplinary standardized data collection for personalized oncology in skin cancer.
Conclusions: Large databases are natural extension of traditional statistical approaches, a valuable and increasingly necessary tool for modern healthcare system. Future analysis of the collected multinational and multicenter data will show whether the use of the system can produce high-quality evidence to support multidisciplinary management of non-melanoma skin cancer and utilizing this information for personalized treatment decisions. PMID: 32395133 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer.
Authors: Gursel SB, Serarslan A, Meydan AD, Okumus N, Yasayacak T Abstract Purpose: The standard treatment for locally advanced stage cervical cancer is definitive radiotherapy, the quality of which affects both survival and side effects. Brachytherapy is a major component of definitive radiotherapy; it is administered using different techniques and applicators. The purpose of this study was to dosimetrically compare tandem ovoid (T-ovoid) and tandem ring (T-ring) brachytherapy treatments. Material and methods: Both applicator sets were applied to the same 20 patients, and treatment plans were made three-dimens...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Prolonged treatment planning can increase real rectal dose in 3D brachytherapy for cervical cancer.
Conclusions: Extended treatment planning time for brachytherapy due to the changes in topography of small pelvis can lead to different dose in high-risk organs than previously planned. It seems that the most significant changes are related to rectum. PMID: 32395135 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients.
Conclusions: Exclusive short course adjuvant VBT is an effective treatment in patients with early-stage endometrial cancer and provides good outcomes in terms of disease local control and DFS, with low rates of toxicity profile. PMID: 32395136 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Multimodality treatment in unresectable cholangiocarcinoma.
Conclusions: Multimodality therapeutic approach in patients with inoperable ECCs could definitely improve their survival time and decrease complications. Survival time is significantly depending on tumor staging, gender, and involvement of liver parenchyma, great vessels, and regional lymph nodes. PMID: 32395137 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Inter-observer and intra-observer variability in reporting vaginal dose points for cervical cancer in high-dose-rate brachytherapy.
Conclusions: There is a need to ensure consistency in vaginal points reporting. The impact of the dosimetric inter- and intra-observer variability should also be considered when dealing with dose tolerances and limits due to the potential dose gradient. PMID: 32395138 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Verification of needle guidance accuracy in pelvic phantom using registered ultrasound and MRI images for intracavitary/interstitial gynecologic brachytherapy.
Conclusions: In this study, we showed that under ideal conditions, rigid registration between MRI images and US images obtained high accuracy for real-time image guidance. Additionally, registered US images provided accurate image guidance during visual needle insertion in IC/IS gynecologic brachytherapy to achieve a combination of effective visualization and image guidance. PMID: 32395139 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Coverage with dosimetric concordance index (CDCI): a tool for evaluating dosimetric impact of inter-observer target variability in brachytherapy.
Authors: Upreti RR, Budrukkar A, Upreti U, Wadasadawala T, Pathak R, Misra S, Gurrum L, Kinhikar RA, Deshpande DD Abstract Purpose: The aim of this study was to propose an index for evaluating dosimetric impact of inter-observer target delineation variability in brachytherapy. Material and methods: The coverage with dosimetric concordance index (CDCI) is expressed as CDCIcommon and CDCIpair. The CDCIcommon is the mean coverage of target volume with common volume irradiated by prescription dose among all observers and represents the condition of worst target coverage. CDCIpair is the generalized form of CDCI, wh...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Does inverse planning improve plan quality in interstitial high-dose-rate breast brachytherapy?
Authors: Major T, Fröhlich G, Mészáros N, Smanykó V, Polgár C Abstract Purpose: To investigate the effect of input parameters for an inverse optimization algorithm, and dosimetrically evaluate and compare clinical treatment plans made by inverse and forward planning in high-dose-rate interstitial breast implants. Material and methods: By using a representative breast implant, input parameters responsible for target coverage and dose homogeneity were changed step-by-step, and their optimal values were determined. Then, effects of parameters on dosimetry of normal tissue and organ...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature.
Conclusions: Combined primary vaginal cancer and POP is an extremely rare clinical entity, with only a few cases reported in the literature. When applying CRT in these cases, critical organ doses may be higher than expected due to the downward descent of the pelvic organs. Especially in elderly patients, a pessary can be used as a non-surgical procedure to restore the anatomy for symptom relief during definitive CRT. Additionally, it allows tumors to be targeted more precisely. PMID: 32395142 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Interstitial high-dose-rate brachytherapy as a boost in synchronous prostate and rectal cancer treatment: case report and literature review.
Authors: Konat-Bąska K, Chicheł A, Staszek-Szewczyk U, Maciejczyk A, Matkowski R Abstract Purpose: Prostate and colorectal cancers are the first and the third most popular malignancies in male population, in which some patients may develop these tumors metachronously or synchronously. At present, there are no standard recommendations, and oncologists need to provide an optimal management for two different cancers with an acceptable risk of possible treatment of adverse effects. Material and methods: This case report presents the treatment of a 61-year-old patient suffering from synchronous prostate and rectal...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Small bowel perforation caused by applicator implantation in high-dose-rate interstitial brachytherapy for recurrent pelvic tumor: a case report.
We describe a case of small bowel perforation caused by applicator implantation in an 82-year-old male patient with recurrence tumor in the pelvis treated with HDR-ISBT. Eventually, the patient underwent laparotomy and partial intestinal resection. We recognized the site where the applicator was inserted into a part of the tumor on the mucosal surface. Pathological examination confirmed that the tumor had infiltrated the small intestine directly and that the infiltrated part had reached the submucosa. This is the first published report about small bowel perforation caused by applicator implantation. In cases where intestin...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A radiobiological study of the schemes with a low number of fractions in high-dose-rate brachytherapy as monotherapy for prostate cancer.
Conclusions: The α/β obtained in our analysis of 22.8 Gy for a range of dose per fraction between 6 and 20.5 Gy was much greater than the one currently estimated for prostate cancer using low doses per fraction. This high value of α/β explains reasonably well the data available in the region of high doses per fraction considered. PMID: 32395145 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evaluation of rectal volume correlation with dosimetric parameters during optimized intracavitary high-dose-rate brachytherapy in cervical cancer.
This study aimed to evaluate the rectal volume and dose-volume histogram (DVH) relationship in high-dose-rate (HDR) brachytherapy in locally advanced cervical cancer. Material and methods: Planning computed tomography of 65 patients who underwent HDR brachytherapy boost as a component of definitive radiotherapy from March 2016 to February 2018 were reviewed. OARs and target volume were re-delineated by a single physician to decrease interobserver variation. Two sets of plan were generated; in the first set, the dose was prescribed to point A with Manchester system loading pattern, while in the second set, the dose was ...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 32395147 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Public health measures, radiotherapy, and the novel coronavirus outbreak.
Authors: Pellizzon ACA PMID: 32395148 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A history of transurethral resection of the prostate should not be a contra-indication for low-dose-rate 125I prostate brachytherapy: results of a prospective Uro-GEC phase-II trial.
Conclusions: The excellent long-term results and low morbidity presented as well as many advantages of prostate brachytherapy over other treatments demonstrates that brachytherapy is an effective treatment for patients with transurethral resection and organ-confined prostate cancer. PMID: 32190063 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Clinical outcomes of low-dose-rate brachytherapy based radiotherapy for intermediate risk prostate cancer.
Conclusions: This study highlights excellent outcomes for intermediate-risk prostate cancer patients, including unfavorable intermediate-risk cases, treated with BED ≥ 200 Gy radiotherapy using LDR brachytherapy. LDR alone with a BED of 200 Gy may be an optimal treatment for both favorable and unfavorable intermediate-risk prostate cancer patients, although a longer follow-up is mandatory to confirm the present findings. PMID: 32190064 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The value of hybrid interstitial tandem and ring applicators for organ at risk dose reduction in small volume cervical cancer.
Authors: Crossley N, Tipton C, Meier T, Sudhoff M, Kharofa J Abstract Purpose: Magnetic resonance imaging (MRI)-guided adaptive brachytherapy is the standard of care for cervical cancer. Hybrid intracavitary/interstitial applicators for bulky tumor (high-risk clinical target volume [HR-CTV]> 30 cc) dose escalation is recommended in the EMBRACE II trial. The value of hybrid applicators for smaller HR-CTV (
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

3D printer-based novel intensity-modulated vaginal brachytherapy applicator: feasibility study.
Conclusions: The novel brachytherapy applicator met the necessary requirements in quality control tests. PMID: 32190066 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evaluation of a new bi-valve vaginal speculum applicator design for gynecologic interstitial brachytherapy.
Conclusions: Our speculum applicator can reproduce a conventional pear-shaped dose distribution. Our current clinical practice will use this applicator, which can improve the patient's treatment results. PMID: 32190067 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric comparison of two different applicators and rectal retraction methods used in inverse optimization-based intracavitary brachytherapy for cervical cancer.
Authors: Biltekin F, Gultekin M, Yilmaz MT, Yildiz F Abstract Purpose: The purpose of this study was to evaluate the dosimetric differences between two different applicators and rectal-retraction methods used in image-guided brachytherapy (IGBT) for locally advanced cervical cancer (LACC). Material and methods: Ten patients with LACC treated with definitive chemoradiotherapy and inverse optimization-based IGBT were included in this study. In each patient, at least one fraction of IGBT was performed using tandem-ovoids (TO) with vaginal gauze packing (VGP) or tandem-ring (TR) with rectal-retractor (RR). High-ris...
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The Medanta AOLO template for locally advanced cancer cervix brachytherapy: design and clinical implementation.
Conclusions: We have developed an easy to use IC + IS type of template/applicator, which was successfully implemented in our clinical practice. PMID: 32190069 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Combined interstitial and surface high-dose-rate brachytherapy treatment of squamous cell carcinoma of the hand.
Conclusions: The first interstitial and surface HDR brachytherapy for cutaneous squamous cell carcinoma of a finger interspace for hand function preservation is presented. The initial experience revealed that brachytherapy was tolerated but with notable acute and late side effects. Treatment did result in tumor shrinkage with organ preservation and function of two rays. A larger cohort of patients will be required for additional conclusions related to long-term clinical benefits in patients who refuse ray amputation. PMID: 32190070 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

First experience of 192Ir source stuck event during high-dose-rate brachytherapy in Japan.
Authors: Kumagai S, Arai N, Takata T, Kon D, Saitoh T, Oba H, Furui S, Kotoku J, Shiraishi K Abstract Purpose: To share the experience of an iridium-192 (192Ir) source stuck event during high-dose-rate (HDR) brachytherapy for cervical cancer. Material and methods: In 2014, we experienced the first source stuck event in Japan when treating cervical cancer with HDR brachytherapy. The cause of the event was a loose screw in the treatment device that interfered with the gear reeling the source. This event had minimal clinical effects on the patient and staff; however, after the event, we created a normal treatment ...
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The role of vaginal brachytherapy in stage I endometrial serous cancer: a systematic review.
Conclusions: These data support the concept that in adequately selected patients, VBT alone may be a suitable radiotherapy technique in women with stage I USC who underwent surgical staging and received adjuvant chemotherapy. PMID: 32190072 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The role of brachytherapy in the management of brain metastases: a systematic review.
Conclusions: For a variety of reasons including absence of physician expertise in brachytherapy, lack of published data on treatment outcomes, and rates of radiation necrosis, brachytherapy is not presently a part of standard paradigm for brain metastases. However, our review indicates brachytherapy as a modality that offers excellent local control and quality of life, and suggested that its use should be further studied. PMID: 32190073 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Can brachytherapy be properly considered in the clinical practice? Trilogy project: The vision of the AIRO (Italian Association of Radiotherapy and Clinical Oncology) Interventional Radiotherapy study group.
Conclusions: The AIRO vision implies that specific strategic interventions must be carried out in the field of national guidelines, education, research, and communication with patients and colleagues of other specialties in an interdisciplinary setting. PMID: 32190074 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

NORTH EUROPE BRACHYTHERAPY USERS MEETING: 10-11 October, 2019Park Inn by Radisson, London Heathrow.
Authors: PMID: 32190075 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 32190076 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - March 21, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 31969906 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Maria Sk łodowska-Curie - the first lady of nuclear physics.
Maria Skłodowska-Curie - the first lady of nuclear physics. J Contemp Brachytherapy. 2019 Dec;11(6):505-509 Authors: Pospieszny T PMID: 31969907 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

HAPPY - Humanity Assurance Protocol in interventional radiotheraPY (brachytherapy) - an AIRO Interventional Radiotherapy Study Group project.
Conclusions: The aim of the present paper was to produce a protocol consisting in intervention that could improve the internal serendipity and emotional state of patients who underwent HDR-IRT. PMID: 31969908 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High precision radiotherapy including intensity-modulated radiation therapy and pulsed-dose-rate brachytherapy for cervical cancer: a retrospective monoinstitutional study.
Conclusions: Our study confirms that the combination of IMRT and PDR-BT can be considered an effective treatment for cervical cancer, ensuring high local control, despite the high percentage of locally advanced disease. PMID: 31969909 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Patterns of cervical cancer brachytherapy in India: results of an online survey supported by the Indian Brachytherapy Society.
Conclusions: Our survey suggested a fairly uniform treatment paradigm for cervical cancer brachytherapy, with a progressive shift from 2D to 3D image-based parameters for planning, with persistence of point A based prescription. Further efforts are needed to augment and ease this transition. PMID: 31969910 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - January 25, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research