High-dose-rate brachytherapy as monotherapy for low- and intermediate-risk prostate cancer: long-term experience of Swedish single-center
CONCLUSIONS: In the present study, HDR mono-brachytherapy was found to be an effective treatment, with mild long-term side effects difficult to differentiate from aging effects. There were no significant differences in PSA regression, PSA failure rate, and toxicity between the different fraction schedules.PMID:34122563 | PMC:PMC8170525 | DOI:10.5114/jcb.2021.105846 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Bengt Johansson Johan Staby Ols én Leif Karlsson Erik Lundin Bo Lennern äs Source Type: research

Analysis of radioactive implant migration in patients treated with iodine-125 seeds for permanent prostate brachytherapy with MRI-classified median lobe hyperplasia
In this study, seed migration was defined as a seed distant from the target (≥ 1.5 cm) and/or with no dosimetric contribution to the target. The MLH patients were divided into 2 MLH groups of mild (
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Koichiro Muraki Chikayuki Hattori Etsuyo Ogo Hiroaki Suefuji Hidehiro Eto Chiyoko Tsuji Yusaku Miyata Toshi Abe Katsuaki Chikui Makoto Nakiri Tsukasa Igawa Tatsuyuki Kakuma Source Type: research

Pulse-dose-rate interstitial brachytherapy in anal squamous cell carcinoma: clinical outcomes and patients' health quality perception
CONCLUSIONS: In this cohort of 42 patients with mainly I and II tumor stages, PDR-BT boost allowed for local control in 88.7% of patients, with only one grade 3 anorectal toxicity.PMID:34122565 | PMC:PMC8170522 | DOI:10.5114/jcb.2021.106247 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: R émi Bourdais Samir Achkar Sophie Espenel Sophie Bockel Laetitia Chauffert-Yvart Florence Ravet de Mellis Minh-Hanh Ta Wassila Boukhelif J érôme Durand-Labrunie Pascal Burtin Christine Haie-Meder Eric Deutsch Cyrus Chargari Source Type: research

The accuracy and dosimetric analysis of 3D-printing non-coplanar template-assisted iodine-125 seed implantation for recurrent chest wall cancer
CONCLUSIONS: 3D-PNCT-assisted CT-guided 125I-SI may be safe and feasible as palliative therapy for non-surgical candidates and painful patients with rCWC.PMID:34122566 | PMC:PMC8170518 | DOI:10.5114/jcb.2021.106250 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Weijuan Jiang Yi Chen Zhe Ji Yuliang Jiang Bin Qiu Haitao Sun Junjie Wang Source Type: research

Reproducibility of vaginal immobilization balloons < em > in situ < /em > overnight for cervical cancer brachytherapy
CONCLUSIONS: This study showed minimal change in balloon volumes, balloons/T+O positioning, or in radiation dose to bladder and rectum when the applicator remained overnight. These findings support that inflatable vaginal immobilization balloons remaining in situ overnight for additional HDR T+O treatments on sequential days, is safe and provides stable dosimetry.PMID:34122567 | PMC:PMC8170519 | DOI:10.5114/jcb.2021.106117 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Uma D Goyal Paras P Mehta Susan Samreth John Gloss Haiyan Cui Denise Roe Shona Dougherty Source Type: research

Non-anesthetist-administered moderate sedation with midazolam and fentanyl for outpatient MRI-aided hybrid intracavitary and interstitial brachytherapy in cervix cancer: a single-institution experience
CONCLUSIONS: Outpatient interstitial brachytherapy with non-anesthetist-administered sedation is achievable and well-tolerated. This method may significantly lessen the burden on hospital resources and has the potential to be cost-effective.PMID:34122568 | PMC:PMC8170517 | DOI:10.5114/jcb.2021.105946 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Kiattisa Sommat Jeannie Yi Xin Lin Melvin Ming Long Chew Chiat Sian Loh Jorene Siew Kee Liew Yong Wee Foo Jin Wei Kwek Tiffany Hennedige June Pheck Suan Goh Tong Khee Tan Source Type: research

Vaginal cuff brachytherapy: do we need to treat to more than a two-centimeter active length?
J Contemp Brachytherapy. 2021 Jun;13(3):294-301. doi: 10.5114/jcb.2021.105971. Epub 2021 May 7.ABSTRACTPURPOSE: American Brachytherapy Society (ABS) guidelines recommend using a 3-5 cm active length (AL) when treating vaginal cuff (VC) in adjuvant setting of endometrial cancer (EC). The purpose of this study was to evaluate local control and toxicity, using an AL of 1 or 2 cm and immobilization with a traditional table-mounted (stand) or patient-mounted (suspenders) device.MATERIAL AND METHODS: Between 2005 and 2019, 247 patients with EC were treated with adjuvant high-dose-rate vaginal cuff (HDR-VC) brachytherapy with or ...
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Garrett L Jensen Parul N Barry Harriet Eldredge-Hindy Scott R Silva Sarah L Todd Kendall P Hammonds Walker R Zimmerman Daniel S Metzinger Moataz N El-Ghamry Source Type: research

Dosimetric comparison between interstitial brachytherapy and volumetric-modulated arc therapy for tumor bed boost in breast cancer
J Contemp Brachytherapy. 2021 Jun;13(3):302-309. doi: 10.5114/jcb.2021.106141. Epub 2021 May 14.ABSTRACTPURPOSE: To dosimetrically compare high-dose-rate interstitial brachytherapy (HDR-BT) with volumetric-modulated arc therapy (VMAT) for tumor bed boost, following breast conservative treatment.MATERIAL AND METHODS: 50 patients with early-stage breast cancer who underwent breast conservation surgery, followed by either HDR-BT (n = 25) of 15 Gy in 6 fractions over a period of 3 days, or VMAT dose of 16 Gy in 8 fractions (n = 25) for tumor bed boost, were retrospectively reviewed. All patients received whole breast irradiati...
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Kannan Periasamy Gunaseelan Karunanithi Shamsudheen Cholayil Kadambari Dharanipragada Vijayprabhu Neelakanadan Source Type: research

Impact of GBBS algorithm on post-mastectomy scar boost irradiation of breast using catheter flap
CONCLUSIONS: The presented data showed how Acuros® BV, algorithm-based calculation in scar boost irradiation of breast, accounting for a mass density of the medium and scatter condition, considered actual dose prediction in a medium.PMID:34122571 | PMC:PMC8170521 | DOI:10.5114/jcb.2021.106288 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Mourougan Sinnatamby Vijayaprabhu Neelakandan Gunaseelan Karunanidhi Saravanan Kandasamy Seenisamy Ramapandian Muniyappan Kannan Elakiya Sampath Source Type: research

Pre-clinical dosimetry of a new six-channel applicator for high-dose-rate treatment of esophageal cancer
CONCLUSIONS: Lateral dose modulation is achievable with the applicator described in this work. The use of TG-186 dose calculation made a small improvement in heterogeneous media.PMID:34122572 | PMC:PMC8170515 | DOI:10.5114/jcb.2021.106049 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Anzi Zhao Shengqiang Gao John Greskovich Douglas Allan Wilkinson Source Type: research

Deep learning applications in automatic segmentation and reconstruction in CT-based cervix brachytherapy
CONCLUSIONS: We proposed a deep learning-based reconstruction method to localize Fletcher applicator in three-dimensional CT images. The achieved accuracy and efficiency confirmed our method as clinically attractive. It paves the way for the automation of brachytherapy treatment planning.PMID:34122573 | PMC:PMC8170523 | DOI:10.5114/jcb.2021.106118 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Hai Hu Qiang Yang Jie Li Pei Wang Bin Tang Xianliang Wang Jinyi Lang Source Type: research

High-dose-rate surface brachytherapy as a treatment option for renal cell carcinoma cutaneous metastases
CONCLUSIONS: HDR sBT can be a valuable treatment option for cutaneous metastatic renal cell carcinoma, especially for patients with significant comorbidities. The treatment provided was associated with low toxicity and excellent clinical outcome.PMID:34122574 | PMC:PMC8170516 | DOI:10.5114/jcb.2021.105947 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Łukasz Raszewski Artur J Chyrek Magdalena Marciniak Wojciech M Burchardt Grzegorz M Biele da Adam Chiche ł Source Type: research

Adjuvant high-dose-rate interstitial brachytherapy for malignant peripheral nerve sheath tumor of the foot: a case report
We report on a patient with primary malignant peripheral nerve sheath tumor in the foot plantar soft tissue, who had no evidence of the disease and no severe late toxicity higher than grade 2, 40 months after receiving amputation of toes and adjuvant interstitial high-dose-rate brachytherapy (HDR-BT). To the best of our knowledge, only a few cases were treated with HDR-BT with this scenario. From our findings, HDR-BT could be a safe and quick treatment option for these types of lesions.PMID:34122575 | PMC:PMC8170520 | DOI:10.5114/jcb.2021.106204 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Andrea Vavassori Elisabetta Pennacchioli Matteo Augugliaro Stefano Durante Samantha Dicuonzo Gian Marco Orsolini Pierpaolo Prestianni Raffaella Cambria Stefania Comi Giovanni Mazzarol Federica Cattani Roberta Lazzari Roberto Orecchia Barbara Alicja Jerecz Source Type: research

Analysis of the efficacy and safety of iodine-125 seeds implantation in the treatment of patients with inoperable early-stage non-small cell lung cancer
J Contemp Brachytherapy. 2021 Jun;13(3):347-357. doi: 10.5114/jcb.2021.106241. Epub 2021 May 18.ABSTRACTPURPOSE: To evaluate the efficacy and safety of iodine-125 (125I) seeds implantation for inoperable early-stage non-small cell lung cancer (NSCLC).MATERIAL AND METHODS: PubMed, Cochrane Library, Embase, China Biology Medicine disc (CBM), China National Knowledge Infrastructure (CNKI), and Wanfang Data were searched from inception until April 2020. Data were collected concerning overall survival, short-term efficacy, and complications. Meta-analysis was performed using R software (version 3.6.3).RESULTS: Nine studies invo...
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Enli Chen Juan Wang Hongtao Zhang Yuwei Zhang Chenfei Jia Xueya Min Yansong Liang Source Type: research

Efficacy and complications of ruthenium-106 brachytherapy for uveal melanoma: a systematic review and meta-analysis
CONCLUSIONS: Although the studies' heterogeneity was high, in a prescription dose ranging from 70 Gy to 250 Gy to the tumor apex, 106Ru brachytherapy seems to be successful in local control of uveal melanoma. The efficacy of 106Ru in controlling uveal melanomas decreased with the increase in tumor thickness. However, these outcomes should be verified in randomized comparative studies.PMID:34122577 | PMC:PMC8170514 | DOI:10.5114/jcb.2021.106191 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - June 14, 2021 Category: Cancer & Oncology Authors: Saeed Karimi Amir Arabi Zahra Siavashpour Toktam Shahraki Iman Ansari Source Type: research

Five-year quality of life in patients with high-risk localized prostate cancer treated with external beam radiotherapy alone versus external beam radiotherapy with high-dose-rate brachytherapy boost: a prospective multicenter study
CONCLUSIONS: After five years of follow-up, EBRT alone or combined with HDR-BT boost had a similar impact on HRQL in patients with high-risk localized PCa. However, patients in the EBRT alone group experienced greater worsening of hormonal domain according to EPIC questionnaire.PMID:34025730 | PMC:PMC8117716 | DOI:10.5114/jcb.2021.103580 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Evelyn Mart ínez Olatz Garin Yolanda Pardo Pablo Fern ández Benjamin Guix Cristina Guti érrez Ana Boladeras Ferran Ferrer Tania Hern ández Adriana Ayala Mikel Egiguren Gema Fern ández V íctor Muñoz V íctor Macías Joan Pera Àngels Pont Montserrat Source Type: research

Salvage brachytherapy for locally recurrent prostate cancer after single-fraction 19 Gy high-dose-rate brachytherapy: toxicity, prostate-specific antigen kinetics, and cancer control
CONCLUSIONS: Salvage HDR-BT 12 × 2 is a feasible and well-tolerated treatment, with acceptable toxicity rates for men with locally recurrent prostate cancer, who failed after HDR-BT with 19 Gy. Moreover, PSA kinetics and cancer control after salvage treatment suggest that this strategy might be efficacious in this clinical setting.PMID:34025731 | PMC:PMC8117711 | DOI:10.5114/jcb.2021.103581 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Esther Mayrata Jose Maria Espinosa David B üchser Francisco Casquero Fernan Su árez Alba Gonz ález Pablo Minguez Jose Fernando P érez I ñigo San Miguel Jon Cacicedo Alfonso G ómez-Iturriaga Source Type: research

Dosimetric comparison of computed tomography-guided iodine-125 seed implantation assisted with and without three-dimensional printing non-coplanar template in locally recurrent rectal cancer: a propensity score matching study
J Contemp Brachytherapy. 2021 Feb;13(1):18-23. doi: 10.5114/jcb.2021.103582. Epub 2021 Feb 18.ABSTRACTPURPOSE: To compare post-implant dosimetric parameters of computed tomography (CT)-guided radioactive iodine-125 (125I) seed (RIS) implantation assisted with and without three-dimensional printing non-coplanar template (3D-PNCT) in locally recurrent rectal cancer (LRRC).MATERIAL AND METHODS: One hundred and fifty-five LRRC patients treated by CT-guided RIS implantation assisted with or without 3D-PNCT from October 2003 to May 2019 were included in this study. Propensity score matching (PSM) method (1 : 1) was used to adjus...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Lu Wang Hao Wang Yuliang Jiang Zhe Ji Fuxin Guo Ping Jiang Bin Qiu Haitao Sun Jinghong Fan Weiyan Li Junjie Wang Source Type: research

Venezia applicator with oblique needles improves clinical target volume coverage in distal parametrial tumor residue compared to parallel needles only
CONCLUSIONS: VeneziaTM applicator permits reproducible application to increase CTV coverage in patients with distal parametrial tumor residue during brachytherapy, while maintaining acceptable dose to OARs.PMID:34025733 | PMC:PMC8117708 | DOI:10.5114/jcb.2021.103583 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Manon Kissel Nathalie Fournier-Bidoz Olivier Henry Sophie Bockel Tamizhanban Kumar Sophie Espenel Cyrus Chargari Source Type: research

Impact of pre-brachytherapy magnetic resonance imaging on dose-volume histogram of locally advanced cervical cancer patients treated with radiotherapy including high-dose-rate brachytherapy
CONCLUSIONS: Pre-brachytherapy MRI may be helpful in selecting suitable candidates for each type of brachytherapy and deliver the recommended doses to the tumor and organs at risk, particularly in cases with large tumors, poor response to concurrent chemoradiotherapy, asymmetrical tumors, severe vaginal invasion, extensive parametrial invasion, and/or corpus invasion.PMID:34025734 | PMC:PMC8117705 | DOI:10.5114/jcb.2021.103584 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Keiko Nemoto Murofushi Toshiki Ishida Keiichiro Baba Kenji Kawakita Tsukasa Saida Sasaki Toshiyuki Okumura Toyomi Sato Hideyuki Sakurai Source Type: research

Accuracy and dosimetric parameters comparison of 3D-printed non-coplanar template-assisted computed tomography-guided iodine-125 seed ablative brachytherapy in pelvic lateral recurrence of gynecological carcinomas
CONCLUSIONS: 3D-PNCT-assisted CT-guided 125I-SAB is safe and feasible for non-central pelvic recurrence of gynecological cancer. All complications are tolerable and mild.PMID:34025735 | PMC:PMC8117710 | DOI:10.5114/jcb.2021.103585 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Ang Qu Ping Jiang Shuhua Wei Yuliang Jiang Zhe Ji Haitao Sun Weiyan Li Yuxia Shao Jinghong Fan Junjie Wang Source Type: research

Plaque brachytherapy in iris and iridociliary melanoma: a systematic review of efficacy and complications
J Contemp Brachytherapy. 2021 Feb;13(1):46-50. doi: 10.5114/jcb.2021.103586. Epub 2021 Feb 18.ABSTRACTPURPOSE: To evaluate the efficacy and vision-threatening complication rate of plaque brachytherapy with iodine-125 (125I), palladium-103 (103Pd), and ruthenium-106 (106Ru) for treatment of iris and iridociliary melanoma.MATERIAL AND METHODS: A literature review was done based on results yielded from searching PubMed, Embase, and Cochrane database, using following key words: iris melanoma, iridociliary melanoma, brachytherapy, iodine-125 brachytherapy, palladium-103 brachytherapy, and ruthenium-106 brachytherapy. Initially,...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Saeed Karimi Amir Arabi Toktam Shahraki Source Type: research

Computed tomography-based flap brachytherapy for non-melanoma skin cancers of the face
CONCLUSIONS: CT-based flap applicator brachytherapy is a valid treatment option for patients with NMSC of the face. This modality offers high rates of local control with acceptable cosmetic outcomes and low rates of toxicity.PMID:34025737 | PMC:PMC8117709 | DOI:10.5114/jcb.2021.103587 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Emile Gogineni Haocheng Cai Dawn Carillo Zaker Rana Beatrice Bloom Louis Potters Hani Gaballa Maged Ghaly Source Type: research

An audit of high dose-rate prostate brachytherapy treatment planning at six Swedish clinics
CONCLUSIONS: Dose constraints for the organs at risk are showing a larger variation than that reflected in compared treatments plans. In all treatment plans in our audit, at least 10 Gy was administered giving a total treatment of 102 Gy EQD2, which is in the upper part of the prescription doses published in the GEC/ESTRO recommendations.PMID:34025738 | PMC:PMC8117718 | DOI:10.5114/jcb.2021.103588 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Frida Dohlmar Sakarias Johansson Torbj örn Larsson Michael Sandborg Åsa Carlsson Tedgren Source Type: research

Use of deformable image registration techniques to estimate dose to organs at risk following prostate external beam radiation therapy and high-dose-rate brachytherapy
CONCLUSIONS: This retrospective study demonstrates significant differences in accumulated rectal dose prediction using different image registration methods. Each method has limitations in its application, and when used with real-time HDR-BT dose planning, awareness of these limitations is essential.PMID:34025739 | PMC:PMC8117714 | DOI:10.5114/jcb.2021.103589 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Marie Vozzo Joel Poder Johnson Yuen Joseph Bucci Annette Haworth Source Type: research

Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology
CONCLUSIONS: Dosimetric results and mechanical accuracy of MCCA show that high-temp resin with SLA 3D printing technique can be used for producing patient-specific MCCA in brachytherapy.PMID:34025740 | PMC:PMC8117717 | DOI:10.5114/jcb.2021.103590 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Reza Mohammadi Zahra Siavashpour Seyed Rashid Hosseini Aghdam Samar Fazli Tibor Major Ali Asghar Rohani Source Type: research

Prostate cancer with nodular bladder invasion (stage T4N1) cured by low-dose-rate brachytherapy with seminal vesicle implantation in combination with external beam radiotherapy of biologically effective dose ≥ 220 Gy: a case report
CONCLUSIONS: Along with previous outstanding data of BED ≥ 220 Gy LDR-based radiotherapy for high-risk and very high-risk prostate cancer patents, including pelvic lymph node metastasis, the present report, in which the patient was treated with BED ≥ 220 Gy of high-dose radiotherapy, LDR brachytherapy in combination with WP EBRT may be an optimal treatment for prostate cancer with nodular bladder invasion with lymph node metastasis (T4N1disease).PMID:34025741 | PMC:PMC8117715 | DOI:10.5114/jcb.2021.103591 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Keisei Okamoto Source Type: research

Novel method of combined photon beam radiotherapy and brachytherapy for treatment of extensive advanced scalp squamous cell carcinoma
J Contemp Brachytherapy. 2021 Feb;13(1):95-100. doi: 10.5114/jcb.2021.103592. Epub 2021 Feb 18.ABSTRACTRadiotherapy of extensive malignant scalp lesions has always been a challenge for radiation oncologists considering the proximity of critical structures. We treated a 39-year-old patient with extensive scalp squamous cell carcinoma with application of adjuvant concurrent chemoradiation and external beam radiation therapy (EBRT), followed by high-dose-rate (HDR) surface brachytherapy boost using an exclusively designed mould, and assessed the radiation dose reaching planning target volume, brain, and optic structures. Comp...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Mostafa Farzin Ramin Jaberi Fatemeh Jafari Mohsen Najafi Kasra Kolahdouzan Source Type: research

A review of brachytherapy physical phantoms developed over the last 20 years: clinical purpose and future requirements
J Contemp Brachytherapy. 2021 Feb;13(1):101-115. doi: 10.5114/jcb.2021.103593. Epub 2021 Feb 18.ABSTRACTWithin the brachytherapy community, many phantoms are constructed in-house, and less commercial development is observed as compared to the field of external beam. Computational or virtual phantom design has seen considerable growth; however, physical phantoms are beneficial for brachytherapy, in which quality is dependent on physical processes, such as accuracy of source placement. Focusing on the design of physical phantoms, this review paper presents a summary of brachytherapy specific phantoms in published journal art...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Sarah Wilby Antony Palmer Wojciech Polak Andrea Bucchi Source Type: research

Letter from the Editor-in-Chief
J Contemp Brachytherapy. 2021 Feb;13(1):VII. doi: 10.5114/jcb.2021.103595. Epub 2021 Feb 18.NO ABSTRACTPMID:34025744 | PMC:PMC8117712 | DOI:10.5114/jcb.2021.103595 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Adam Chiche ł Source Type: research

Five-year quality of life in patients with high-risk localized prostate cancer treated with external beam radiotherapy alone versus external beam radiotherapy with high-dose-rate brachytherapy boost: a prospective multicenter study
CONCLUSIONS: After five years of follow-up, EBRT alone or combined with HDR-BT boost had a similar impact on HRQL in patients with high-risk localized PCa. However, patients in the EBRT alone group experienced greater worsening of hormonal domain according to EPIC questionnaire.PMID:34025730 | PMC:PMC8117716 | DOI:10.5114/jcb.2021.103580 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Evelyn Mart ínez Olatz Garin Yolanda Pardo Pablo Fern ández Benjamin Guix Cristina Guti érrez Ana Boladeras Ferran Ferrer Tania Hern ández Adriana Ayala Mikel Egiguren Gema Fern ández V íctor Muñoz V íctor Macías Joan Pera Àngels Pont Montserrat Source Type: research

Salvage brachytherapy for locally recurrent prostate cancer after single-fraction 19 Gy high-dose-rate brachytherapy: toxicity, prostate-specific antigen kinetics, and cancer control
CONCLUSIONS: Salvage HDR-BT 12 × 2 is a feasible and well-tolerated treatment, with acceptable toxicity rates for men with locally recurrent prostate cancer, who failed after HDR-BT with 19 Gy. Moreover, PSA kinetics and cancer control after salvage treatment suggest that this strategy might be efficacious in this clinical setting.PMID:34025731 | PMC:PMC8117711 | DOI:10.5114/jcb.2021.103581 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Esther Mayrata Jose Maria Espinosa David B üchser Francisco Casquero Fernan Su árez Alba Gonz ález Pablo Minguez Jose Fernando P érez I ñigo San Miguel Jon Cacicedo Alfonso G ómez-Iturriaga Source Type: research

Dosimetric comparison of computed tomography-guided iodine-125 seed implantation assisted with and without three-dimensional printing non-coplanar template in locally recurrent rectal cancer: a propensity score matching study
J Contemp Brachytherapy. 2021 Feb;13(1):18-23. doi: 10.5114/jcb.2021.103582. Epub 2021 Feb 18.ABSTRACTPURPOSE: To compare post-implant dosimetric parameters of computed tomography (CT)-guided radioactive iodine-125 (125I) seed (RIS) implantation assisted with and without three-dimensional printing non-coplanar template (3D-PNCT) in locally recurrent rectal cancer (LRRC).MATERIAL AND METHODS: One hundred and fifty-five LRRC patients treated by CT-guided RIS implantation assisted with or without 3D-PNCT from October 2003 to May 2019 were included in this study. Propensity score matching (PSM) method (1 : 1) was used to adjus...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Lu Wang Hao Wang Yuliang Jiang Zhe Ji Fuxin Guo Ping Jiang Bin Qiu Haitao Sun Jinghong Fan Weiyan Li Junjie Wang Source Type: research

Venezia applicator with oblique needles improves clinical target volume coverage in distal parametrial tumor residue compared to parallel needles only
CONCLUSIONS: VeneziaTM applicator permits reproducible application to increase CTV coverage in patients with distal parametrial tumor residue during brachytherapy, while maintaining acceptable dose to OARs.PMID:34025733 | PMC:PMC8117708 | DOI:10.5114/jcb.2021.103583 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Manon Kissel Nathalie Fournier-Bidoz Olivier Henry Sophie Bockel Tamizhanban Kumar Sophie Espenel Cyrus Chargari Source Type: research

Impact of pre-brachytherapy magnetic resonance imaging on dose-volume histogram of locally advanced cervical cancer patients treated with radiotherapy including high-dose-rate brachytherapy
CONCLUSIONS: Pre-brachytherapy MRI may be helpful in selecting suitable candidates for each type of brachytherapy and deliver the recommended doses to the tumor and organs at risk, particularly in cases with large tumors, poor response to concurrent chemoradiotherapy, asymmetrical tumors, severe vaginal invasion, extensive parametrial invasion, and/or corpus invasion.PMID:34025734 | PMC:PMC8117705 | DOI:10.5114/jcb.2021.103584 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Keiko Nemoto Murofushi Toshiki Ishida Keiichiro Baba Kenji Kawakita Tsukasa Saida Sasaki Toshiyuki Okumura Toyomi Sato Hideyuki Sakurai Source Type: research

Accuracy and dosimetric parameters comparison of 3D-printed non-coplanar template-assisted computed tomography-guided iodine-125 seed ablative brachytherapy in pelvic lateral recurrence of gynecological carcinomas
CONCLUSIONS: 3D-PNCT-assisted CT-guided 125I-SAB is safe and feasible for non-central pelvic recurrence of gynecological cancer. All complications are tolerable and mild.PMID:34025735 | PMC:PMC8117710 | DOI:10.5114/jcb.2021.103585 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Ang Qu Ping Jiang Shuhua Wei Yuliang Jiang Zhe Ji Haitao Sun Weiyan Li Yuxia Shao Jinghong Fan Junjie Wang Source Type: research

Plaque brachytherapy in iris and iridociliary melanoma: a systematic review of efficacy and complications
J Contemp Brachytherapy. 2021 Feb;13(1):46-50. doi: 10.5114/jcb.2021.103586. Epub 2021 Feb 18.ABSTRACTPURPOSE: To evaluate the efficacy and vision-threatening complication rate of plaque brachytherapy with iodine-125 (125I), palladium-103 (103Pd), and ruthenium-106 (106Ru) for treatment of iris and iridociliary melanoma.MATERIAL AND METHODS: A literature review was done based on results yielded from searching PubMed, Embase, and Cochrane database, using following key words: iris melanoma, iridociliary melanoma, brachytherapy, iodine-125 brachytherapy, palladium-103 brachytherapy, and ruthenium-106 brachytherapy. Initially,...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Saeed Karimi Amir Arabi Toktam Shahraki Source Type: research

Computed tomography-based flap brachytherapy for non-melanoma skin cancers of the face
CONCLUSIONS: CT-based flap applicator brachytherapy is a valid treatment option for patients with NMSC of the face. This modality offers high rates of local control with acceptable cosmetic outcomes and low rates of toxicity.PMID:34025737 | PMC:PMC8117709 | DOI:10.5114/jcb.2021.103587 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Emile Gogineni Haocheng Cai Dawn Carillo Zaker Rana Beatrice Bloom Louis Potters Hani Gaballa Maged Ghaly Source Type: research

An audit of high dose-rate prostate brachytherapy treatment planning at six Swedish clinics
CONCLUSIONS: Dose constraints for the organs at risk are showing a larger variation than that reflected in compared treatments plans. In all treatment plans in our audit, at least 10 Gy was administered giving a total treatment of 102 Gy EQD2, which is in the upper part of the prescription doses published in the GEC/ESTRO recommendations.PMID:34025738 | PMC:PMC8117718 | DOI:10.5114/jcb.2021.103588 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Frida Dohlmar Sakarias Johansson Torbj örn Larsson Michael Sandborg Åsa Carlsson Tedgren Source Type: research

Use of deformable image registration techniques to estimate dose to organs at risk following prostate external beam radiation therapy and high-dose-rate brachytherapy
CONCLUSIONS: This retrospective study demonstrates significant differences in accumulated rectal dose prediction using different image registration methods. Each method has limitations in its application, and when used with real-time HDR-BT dose planning, awareness of these limitations is essential.PMID:34025739 | PMC:PMC8117714 | DOI:10.5114/jcb.2021.103589 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Marie Vozzo Joel Poder Johnson Yuen Joseph Bucci Annette Haworth Source Type: research

Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology
CONCLUSIONS: Dosimetric results and mechanical accuracy of MCCA show that high-temp resin with SLA 3D printing technique can be used for producing patient-specific MCCA in brachytherapy.PMID:34025740 | PMC:PMC8117717 | DOI:10.5114/jcb.2021.103590 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Reza Mohammadi Zahra Siavashpour Seyed Rashid Hosseini Aghdam Samar Fazli Tibor Major Ali Asghar Rohani Source Type: research

Prostate cancer with nodular bladder invasion (stage T4N1) cured by low-dose-rate brachytherapy with seminal vesicle implantation in combination with external beam radiotherapy of biologically effective dose ≥ 220 Gy: a case report
CONCLUSIONS: Along with previous outstanding data of BED ≥ 220 Gy LDR-based radiotherapy for high-risk and very high-risk prostate cancer patents, including pelvic lymph node metastasis, the present report, in which the patient was treated with BED ≥ 220 Gy of high-dose radiotherapy, LDR brachytherapy in combination with WP EBRT may be an optimal treatment for prostate cancer with nodular bladder invasion with lymph node metastasis (T4N1disease).PMID:34025741 | PMC:PMC8117715 | DOI:10.5114/jcb.2021.103591 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Keisei Okamoto Source Type: research

Novel method of combined photon beam radiotherapy and brachytherapy for treatment of extensive advanced scalp squamous cell carcinoma
J Contemp Brachytherapy. 2021 Feb;13(1):95-100. doi: 10.5114/jcb.2021.103592. Epub 2021 Feb 18.ABSTRACTRadiotherapy of extensive malignant scalp lesions has always been a challenge for radiation oncologists considering the proximity of critical structures. We treated a 39-year-old patient with extensive scalp squamous cell carcinoma with application of adjuvant concurrent chemoradiation and external beam radiation therapy (EBRT), followed by high-dose-rate (HDR) surface brachytherapy boost using an exclusively designed mould, and assessed the radiation dose reaching planning target volume, brain, and optic structures. Comp...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Mostafa Farzin Ramin Jaberi Fatemeh Jafari Mohsen Najafi Kasra Kolahdouzan Source Type: research

A review of brachytherapy physical phantoms developed over the last 20 years: clinical purpose and future requirements
J Contemp Brachytherapy. 2021 Feb;13(1):101-115. doi: 10.5114/jcb.2021.103593. Epub 2021 Feb 18.ABSTRACTWithin the brachytherapy community, many phantoms are constructed in-house, and less commercial development is observed as compared to the field of external beam. Computational or virtual phantom design has seen considerable growth; however, physical phantoms are beneficial for brachytherapy, in which quality is dependent on physical processes, such as accuracy of source placement. Focusing on the design of physical phantoms, this review paper presents a summary of brachytherapy specific phantoms in published journal art...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Sarah Wilby Antony Palmer Wojciech Polak Andrea Bucchi Source Type: research

Letter from the Editor-in-Chief
J Contemp Brachytherapy. 2021 Feb;13(1):VII. doi: 10.5114/jcb.2021.103595. Epub 2021 Feb 18.NO ABSTRACTPMID:34025744 | PMC:PMC8117712 | DOI:10.5114/jcb.2021.103595 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Adam Chiche ł Source Type: research

Five-year quality of life in patients with high-risk localized prostate cancer treated with external beam radiotherapy alone versus external beam radiotherapy with high-dose-rate brachytherapy boost: a prospective multicenter study
CONCLUSIONS: After five years of follow-up, EBRT alone or combined with HDR-BT boost had a similar impact on HRQL in patients with high-risk localized PCa. However, patients in the EBRT alone group experienced greater worsening of hormonal domain according to EPIC questionnaire.PMID:34025730 | PMC:PMC8117716 | DOI:10.5114/jcb.2021.103580 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Evelyn Mart ínez Olatz Garin Yolanda Pardo Pablo Fern ández Benjamin Guix Cristina Guti érrez Ana Boladeras Ferran Ferrer Tania Hern ández Adriana Ayala Mikel Egiguren Gema Fern ández V íctor Muñoz V íctor Macías Joan Pera Àngels Pont Montserrat Source Type: research

Salvage brachytherapy for locally recurrent prostate cancer after single-fraction 19 Gy high-dose-rate brachytherapy: toxicity, prostate-specific antigen kinetics, and cancer control
CONCLUSIONS: Salvage HDR-BT 12 × 2 is a feasible and well-tolerated treatment, with acceptable toxicity rates for men with locally recurrent prostate cancer, who failed after HDR-BT with 19 Gy. Moreover, PSA kinetics and cancer control after salvage treatment suggest that this strategy might be efficacious in this clinical setting.PMID:34025731 | PMC:PMC8117711 | DOI:10.5114/jcb.2021.103581 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Esther Mayrata Jose Maria Espinosa David B üchser Francisco Casquero Fernan Su árez Alba Gonz ález Pablo Minguez Jose Fernando P érez I ñigo San Miguel Jon Cacicedo Alfonso G ómez-Iturriaga Source Type: research

Dosimetric comparison of computed tomography-guided iodine-125 seed implantation assisted with and without three-dimensional printing non-coplanar template in locally recurrent rectal cancer: a propensity score matching study
J Contemp Brachytherapy. 2021 Feb;13(1):18-23. doi: 10.5114/jcb.2021.103582. Epub 2021 Feb 18.ABSTRACTPURPOSE: To compare post-implant dosimetric parameters of computed tomography (CT)-guided radioactive iodine-125 (125I) seed (RIS) implantation assisted with and without three-dimensional printing non-coplanar template (3D-PNCT) in locally recurrent rectal cancer (LRRC).MATERIAL AND METHODS: One hundred and fifty-five LRRC patients treated by CT-guided RIS implantation assisted with or without 3D-PNCT from October 2003 to May 2019 were included in this study. Propensity score matching (PSM) method (1 : 1) was used to adjus...
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Lu Wang Hao Wang Yuliang Jiang Zhe Ji Fuxin Guo Ping Jiang Bin Qiu Haitao Sun Jinghong Fan Weiyan Li Junjie Wang Source Type: research

Venezia applicator with oblique needles improves clinical target volume coverage in distal parametrial tumor residue compared to parallel needles only
CONCLUSIONS: VeneziaTM applicator permits reproducible application to increase CTV coverage in patients with distal parametrial tumor residue during brachytherapy, while maintaining acceptable dose to OARs.PMID:34025733 | PMC:PMC8117708 | DOI:10.5114/jcb.2021.103583 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Manon Kissel Nathalie Fournier-Bidoz Olivier Henry Sophie Bockel Tamizhanban Kumar Sophie Espenel Cyrus Chargari Source Type: research

Impact of pre-brachytherapy magnetic resonance imaging on dose-volume histogram of locally advanced cervical cancer patients treated with radiotherapy including high-dose-rate brachytherapy
CONCLUSIONS: Pre-brachytherapy MRI may be helpful in selecting suitable candidates for each type of brachytherapy and deliver the recommended doses to the tumor and organs at risk, particularly in cases with large tumors, poor response to concurrent chemoradiotherapy, asymmetrical tumors, severe vaginal invasion, extensive parametrial invasion, and/or corpus invasion.PMID:34025734 | PMC:PMC8117705 | DOI:10.5114/jcb.2021.103584 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 24, 2021 Category: Cancer & Oncology Authors: Keiko Nemoto Murofushi Toshiki Ishida Keiichiro Baba Kenji Kawakita Tsukasa Saida Sasaki Toshiyuki Okumura Toyomi Sato Hideyuki Sakurai Source Type: research