Interventional radiotherapy as exclusive treatment for primary nasal vestibule cancer: single-institution experience.
Conclusions: This study confirms that interventional radiotherapy could be considered as a definitive treatment in nasal vestibule cancer with excellent oncological and cosmetic outcomes. PMID: 33299429 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Feasibility and early toxicity of focal or partial brachytherapy in prostate cancer patients.
Authors: Kim TH, Kim JN, Yu YD, Lee SR, Hong YK, Shin HS, Park DS Abstract Purpose: The aim of this study was to compare short-term oncologic outcomes and toxicity of focal or partial low-dose-rate brachytherapy (focal/partial LDR-BT) with whole gland low-dose-rate brachytherapy (whole LDR-BT) in localized prostate cancer patients. Material and methods: Medical records of eligible patients who underwent focal/partial LDR-BT and whole LDR-BT between 2015 and 2017 at our institution were reviewed retrospectively. Clinical characteristics and pathologic outcomes were compared between focal/partial LDR-BT group and...
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Endovascular implantation of iodine-125 seed strand combined and stent placement for locally advanced pancreatic ductal adenocarcinoma with vascular invasion: a prospective single-arm pilot study.
Conclusions: Endovascular brachytherapy using 125I seed strand and stent placement may be a safe and effective treatment option for locally advanced pancreatic duct adenocarcinoma with vascular invasion. PMID: 33299431 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate brachytherapy using Leipzig applicators for non-melanoma localized skin cancer.
Authors: Pellizzon ACA, Fogaroli R, Chen MJ, Maia P, Gondim G, Guedes DC, Ramos H, Silva MLG Abstract Purpose: Technological advances with commercial production of surface applicators allowed high-dose-rate (HDR) afterloading brachytherapy to overpass challenges associated with the delivery of superficial radiation when treating non-melanoma skin cancer (NMSC). We reviewed our single institutional experience using HDR to treat basal (BCC) and squamous cell (SCC) carcinomas. Material and methods: A retrospective review of all patients treated with HDR and Leipzig-style applicators for NMSC at the Radiation Oncol...
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Excess dose-related parameters (Vex, Rex, and iRex): novel predictors and late toxicity correlations in cervical cancer image-guided adaptive brachytherapy.
Conclusions: Excess dose-related parameters, including Vex, Rex, and iRex, showed significant mean differences and parameter-toxicity relationships for late GI but not for GU toxicities. Positive NRIs suggest iRex60 utilization for spatial control of dose expansion, in addition to high-dose control with OAR small volumes. Further investigations are needed to define the optimum use of these predictors. PMID: 33299433 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Predictive value of Excel forms based on an automatic calculation of dose equivalent in 2 Gy per fraction in adaptive brachytherapy for cervical cancer.
Conclusions: The in-house designed application has the function of quickly reading dose-volume histogram (DVH) parameters from the treatment planning system, which allows for balance between the total dose to target volumes and organs at risk (OARs). Excel forms based on EQD2 automatic calculation presents high predictive accuracy. PMID: 33299434 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Biological dose summation of external beam radiotherapy for the whole breast and image-guided high-dose-rate interstitial brachytherapy boost in early-stage breast cancer.
Conclusions: Based on our biological dose summation method, the total dose of PTV in the breast is higher using BT boost than with EBRT. BT boost yields lower skin, lung, and heart doses, but higher dose to ribs. UDC overestimates lung and ribs doses. PMID: 33299435 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Development of a novel and low-cost anthropomorphic pelvis phantom for 3D dosimetry in radiotherapy.
Conclusions: A customized pelvis phantom was successfully built and assessed to confirm properties similar to body tissues. Additionally, no significant perturbation effect with different bead resolutions was presented by the external TPS, with 0.1 mm dose grid resolution. PMID: 33299436 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Feasibility of interstitial stepping-source electronic brachytherapy to locally inoperable tumors.
Conclusions: Stepping-source EBT allowed for a conformal treatment of inoperable interstitial tumors with similar D90. Fewer trajectories were required for EBT in majority of cases. PMID: 33299437 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Transvaginal artificial ascites infusion as a spacer in gynecological brachytherapy: a novel technique.
Authors: Karube M, Murakami N, Okamoto H, Okuma K, Kashihara T, Takahashi K, Kaneda T, Inaba K, Igaki H, Kato T, Itami J Abstract This is a first paper to report on artificial ascites infusion via vaginal wall for pelvic interstitial brachytherapy. Artificial ascites is commonly used for treating liver tumors, with radiofrequency ablation and percutaneous artificial ascites infusion through the abdominal wall for pelvic brachytherapy has been previously reported by our group. However, the trans-abdominal needle approach under ultrasound guidance is unreliable due to poor visualization resulting in fluid injection i...
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report.
We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. To the best of our knowledge, this is the first case treated with HDR-BT in this scenario. PMID: 33299439 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Artificial intelligence (AI) and interventional radiotherapy (brachytherapy): state of art and future perspectives.
Conclusions: AI may contribute to improve clinical outcomes through the application of predictive models and DSS optimization. This approach could lead to reducing time-consuming repetitive tasks, healthcare costs, and improving treatment quality assurance and patient's assistance in IRT. PMID: 33299440 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy in head and neck malignancies: Indian Brachytherapy Society (IBS) recommendations and guidelines.
Conclusions: IBS provided a consensus statement and guidelines for the head and neck brachytherapy and believed that these recommendations will overcome the fear of practicing radiation oncologists. This should generate interest amongst students and will help radiation oncologists all across the country to use the art of brachytherapy carefully in HNC patients, with better curative and salvage options. PMID: 33299441 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The role of imaging in head and neck cancer: An overview of different imaging modalities in primary diagnosis and staging of the disease.
Authors: Vishwanath V, Jafarieh S, Rembielak A Abstract Radiology has an essential role in diagnosis, staging, and management in all subspecialties related to oncology. It has a broad utility from its use as an initial screening tool for cancer detection, followed by staging and surveillance of disease as well as the delivery of appropriate treatment regimens. In order to plan a treatment, the use of different modalities of radiological imaging are a key factor for pre-treatment planning and staging of the extent of disease in accordance with tumor-node-metastasis (TNM) system for highly conformal treatments, such ...
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

7th Biannual Conference of the Polish Brachytherapy Society - presidential digest.
Authors: Wojcieszek P PMID: 33299443 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 33299444 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 11, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Eye plaque brachytherapy versus enucleation for ocular melanoma: an analysis from the National Cancer Database.
Authors: Messer JA, Zuhour RJ, Haque W, Lewis GD, Schefler AC, Wong A, Bernicker EH, Chevez-Barrios P, Quan EM, Farach A, Butler EB, Hatch SS, Teh BS Abstract Purpose: There is no current randomized data comparing the efficacy of brachytherapy and enucleation for patients with larger sized tumors. The purpose of the present study was to use a large, contemporary database to determine current practice patterns and compare survival outcomes between different management options for patients with choroidal melanoma of various sizes. Material and methods: The National Cancer Database was queried (2004-2014) for hist...
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric differences between cesium-131 and iodine-125 brachytherapy for the treatment of resected brain metastases.
Authors: Yondorf MZ, Faraz S, Smith AW, Sabbas A, Parashar B, Schwartz TH, Wernicke AG Abstract Purpose: To compare treatment plans and evaluate dosimetric characteristics of permanent cesium-131 (131Cs) vs. iodine-125 (125I) implants used in brain brachytherapy. Material and methods: Twenty-four patients with 131Cs implants from a prospective phase I/II trial were re-planned with 125I implants. In order to evaluate the volume of brain tissue exposed to radiation therapy (RT), the dose volume histogram was generated for both radioisotopes. To evaluate the dosimetric differences of the two radioisotopes we compa...
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of post-implant dosimetrics between intraoperatively built custom-linked seeds and loose seeds by sector analysis at 24 hours and 1 month for localized prostate cancer.
Authors: Okazaki E, Kuratsukuri K, Nishikawa T, Tanaka T, Sakagami M, Shibuya K Abstract Purpose: To compare post-implant dosimetrics between intraoperatively built custom-linked (IBCL) seeds and loose seeds (LS) at 24 hours and 1 month by sector analysis, and to evaluate the effect of IBCL seeds with regard to change in dosimetric parameters, in patients with prostate cancer treated with brachytherapy. Material and methods: Consecutive patients treated for localized prostate cancer who received definitive brachytherapy between March 2013 and October 2017 were retrospectively analyzed. Prostate V100 (PV100), pr...
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evaluation of transrectal ultrasound-based dosimetry for brachytherapy of prostate cancer: a single-center experience.
Conclusions: Intraoperative TRUS can be used for dosimetric verification of BT for prostate cancer. PMID: 33293971 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Iodine-125 seed implantation treatment of lung metastases < 2.5 cm using 5-ml syringe as a guide.
Iodine-125 seed implantation treatment of lung metastases
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Computed tomography-guided implantation of 125I radioactive seeds in patients with malignant airway compression induced by advanced lung cancer: effectiveness and safety in 40 patients.
Conclusions: For patients with malignant airway compression induced by advanced lung cancer, implantation with 125I seed is a safe and effective alternative treatment option. PMID: 33293973 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Interstitial high-dose-rate brachytherapy using cobalt-60 source for cervical cancer: dosimetric and clinical outcomes from a single institute.
Conclusions: The dosimetric parameters, local control and toxicities of high-dose-rate interstitial brachytherapy in cervical cancer patients treated by 60Co radioactive source are similar, compared to available literature using iridium-192 (192Ir) source. PMID: 33293974 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Combined external pelvic chemoradiotherapy and image-guided adaptive brachytherapy in treatment of advanced cervical carcinoma: experience from a single institution.
Conclusions: The local and pelvic control rates were excellent in this series. The IGABT was an important part of the treatment schedule and could probably not be replaced by increasing the external pelvic dose. Adenocarcinomas seemed to benefit from the addition of interstitial needles. Late serious toxicity was rare. PMID: 33293975 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of computed tomography- and magnetic resonance imaging-based target delineation for cervical cancer brachytherapy.
Conclusions: The delineated ranges of CTVHR were significantly over-estimated on CT compared with MRI. D98 and D90 of CTVHR-CT were lower than CTVHR-MR. DSC and ΔV of CTVHR and CTVIR were similar to each other; however, there was a difference in terms of HD. CT images regarding pre-BT MR images for delineating were not enough and MRI fusion is still required. PMID: 33293976 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Application of transrectal ultrasound in guiding interstitial brachytherapy for advanced cervical cancer.
Conclusions: Transrectal ultrasound showed strong agreement with MRI results in determining the position of the inserted needles. Transrectal ultrasound is a useful tool for guided interstitial brachytherapy and is appropriate for widespread use in the treatment of locally advanced cervical cancer. PMID: 33293977 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of catheter reconstruction techniques for the lunar ovoid channels of the VeneziaTM applicator.
Conclusions: Relative to the SPS-based plan, large local dose discrepancies were reduced, but not eliminated, using the manufacturer's source path model. The choice of reconstruction technique was found to have relatively limited impact on DVH parameters for regions outside of the vaginal mucosa. PMID: 33293978 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy practice during the COVID-19 pandemic: a review on the practice changes.
Authors: Barthwal M, Pareek V, Mallick S, Sharma DN Abstract The COVID-19 pandemic has caused a havoc across the globe, and has significantly affected oncology services, especially radiation therapy due to the need of social distancing as a measure for the pandemic mitigation. Brachytherapy, being an integral part of radiation therapy, posts a dilemma related to the practice of evidence-based oncology. It requires a significant amount of resources and personnel, thereby increasing the risk of exposure to the virus. There has been a significant amount of papers published providing the best available alternatives to ...
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

INTERACTS (INTErventional Radiotherapy ACtive Teaching School) consensus conference on sarcoma interventional radiotherapy (brachytherapy) endorsed by AIRO (Italian Association of Radiotherapy and Clinical Oncology).
Conclusions: The consensus conference demonstrated that interventional radiotherapy must be considered by a multidisciplinary management of patients affected by sarcoma. PMID: 33293980 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Complex and prolonged skin toxicity after superficial brachytherapy for basal cell carcinoma on the lower leg.
Authors: Rembielak A Abstract Superficial brachytherapy (BT) is used to treat skin cancers at various locations. In areas of poor vascularization, which are subjected to constant trauma, such as extremities, radiotherapy may cause prolonged healing, poorly treatable chronic ulcerations, and even necrosis, requiring subsequent surgical intervention. In this case study, we report on an elderly patient with basal cell carcinoma located on lower leg that was treated with superficial BT. The cancer was cured, but the patient developed complex and prolonged skin toxicity that eventually resolved after 15 months. PMID...
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 33293982 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - December 10, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate Brachytherapy as Adjuvant Local rEirradiation for Salvage Treatment of Recurrent breAst cancer (BALESTRA): a retrospective mono-institutional study.
Conclusions: Our preliminary analysis showed that HDR-BT is a feasible treatment for partial breast reirradiation offering very low complications rate and fast procedure. Higher patients' cohort is warranted in order to define the role of this treatment modality in the breast conservative management of local recurrence. PMID: 32695191 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Patient and physician reported toxicity with two-fraction definitive high-dose-rate prostate brachytherapy: the impact of implant interval.
Conclusions: HDR brachytherapy for prostate cancer is a well-tolerated treatment. The interval between treatments is not associated with differences in patient-reported QOL or physician-graded toxicities. PMID: 32695192 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The efficacy of the combination of percutaneous transhepatic biliary drainage and 125I stranded seeds for malignant bile duct obstruction treatment.
Authors: Li S, Li B, Li L, Yang X, Xu F, Wang W Abstract Purpose: To investigate the efficacy of percutaneous transhepatic biliary drainage (PTBD) combined with iodine-125 (125I) stranded seeds for the treatment of malignant bile duct obstruction (MBO). Material and methods: A retrospective study was performed on 58 consecutive MBO patients. Twenty patients underwent PTBD combined with 125I stranded seeds (group A). Thirty-eight patients underwent percutaneous trans-hepatic biliary drainage (group B). Total bilirubin, direct bilirubin, and indirect bilirubin levels were compared preoperatively, 1-week, 1-month,...
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Iodine-125 seed implantation for residual hepatocellular carcinoma or cholangiocellular carcinoma in challenging locations after transcatheter arterial chemoembolization: Initial experience and findings.
Conclusions: CT-guided ISI for HCC or CCC lesions in challenging locations after TACE is both highly effective and safe. PMID: 32695194 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate brachytherapy of primary cutaneous B-cell lymphoma: the first reported case series.
Conclusions: HDR-BT allows for achieving high local control of CBCLs with relatively low-late toxicity in the form of skin discoloration in most patients. PMID: 32695195 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric evaluation of vaginal cuff brachytherapy planning in cervical and endometrial cancer patients.
Conclusions: VCB planning with the use of CT is essential. CT can facilitate the selection of optimal cylinder size to reduce the occurrence of large AGs. A few percent of plans require correction of dose distribution because of hot spots in OARs and the presence of AGs. Enema before cylinder insertion does not influence rectosigmoid Dmax and D2cm3. The analysis revealed no bladder volume effect on bladder doses Dmax and D2cm3. PMID: 32695196 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Analysis of clinical utilization of ring applicator for combined intracavitary/interstitial image-guided brachytherapy treatment in Chinese patients with locally advanced cervical cancer.
Authors: Zhao Z, Zhang N, Liu Y, Wu N, Mao Z, Yang W, Cheng G Abstract Purpose: To analyze the results of clinical utilization of ring applicator for combined intracavitary (IC)/interstitial (IS) image-guided brachytherapy (BT) technique in locally advanced cervical cancer (LACC), and to explore the application conditions of IC/IS BT approach with this applicator for Chinese patients. Material and methods: IC/IS BT was performed in total of 95 LACC patients, who already received external beam radiotherapy. In forty-three of these patients, utilization of ring applicator in brachytherapy was done, including IC/I...
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Biological dose summation of intensity-modulated arc therapy and image-guided high-dose-rate interstitial brachytherapy in intermediate- and high-risk prostate cancer.
Conclusions: Based on our biological dose summation method, the total dose of prostate is higher using BT boost than the IMAT. BT boost yields lower rectum, bladder, and hips doses, but higher dose to urethra. UDC overestimates rectum and bladder dose and underestimates the dose to urethra. PMID: 32695198 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single-fraction low-energy electronic brachytherapy for conjunctival lymphoma.
Conclusions: Single dose kilovoltage brachytherapy was effective and safe in this small cohort of patients. Based on the literature, there is an evidence that local treatment in short-course radiotherapy is effective and should be considered amongst therapeutic options for these patients; however, this novel approach should be evaluated prospectively in a larger cohort. PMID: 32695199 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy.
Conclusions: Our palliative treatment technique appears to be safe, effective, and less invasive, and could be a treatment option for symptomatic patients with head and neck cancer. PMID: 32695200 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Comparison of initial computed tomography-based target delineation and subsequent magnetic resonance imaging-based target delineation for cervical cancer brachytherapy.
Conclusions: The use of asynchronous MRI for target delineation, with co-registration to CT for each fraction of brachytherapy was associated with higher D90 to the HR-CTV. We observed slightly higher D2cc rectal doses with MRI, but cumulative rectal doses were within accepted thresholds. High-risk target volumes were not consistently increased or decreased, but MRI fusion was associated with target volume changes greater than 20% in over half of the treated patients. PMID: 32695201 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The 100 most cited articles in prostate cancer brachytherapy: systematic review and bibliometric analysis.
Conclusions: The bibliometric analysis presents a detailed list of the 100 most cited articles in prostate cancer brachytherapy. There are clear recommendations for treatment with prostate cancer brachytherapy. The goal of prostate cancer brachytherapy is to improve long-term outcomes and quality of life. PMID: 32695202 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy in cervical cancer radiotherapy during COVID-19 pandemic crisis: problems and prospects.
This article presents in detail the issues and possible solutions with currently available literature for COVID-19 and radiation, in particular brachytherapy management of locally advanced cervical cancers. The review attempts to provide possible explanations and pathways based on COVID-19 testing, brachytherapy processes including application, imaging, and fractionation, keeping in mind the overall treatment time. PMID: 32695203 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image-guided interstitial brachytherapy boost for nasopharyngeal carcinoma: technical aspects.
Authors: Murakami N, Cheng G, Yoshimoto S, Itami J Abstract Nasopharyngeal cancer generally responds well to concurrent chemoradiotherapy (CCRT). However, there is a small group of patients who respond poorly to CCRT, and experience local residual tumor or local relapse. Although several attempts have been performed to such a group of patients including re-irradiation with external beam radiation therapy (EBRT) or salvage surgery, clinical results remain unsatisfactory. Intracavitary brachytherapy (ICBT) boost after CCRT with EBRT has been explored, however, its efficacy is limited to those with superficial residua...
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Letter from the Editor-in-Chief.
Authors: Chicheł A PMID: 32695205 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - July 24, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

SKIN-COBRA (Consortium for Brachytherapy data Analysis) ontology: The first step towards interdisciplinary standardized data collection for personalized oncology in skin cancer.
Conclusions: Large databases are natural extension of traditional statistical approaches, a valuable and increasingly necessary tool for modern healthcare system. Future analysis of the collected multinational and multicenter data will show whether the use of the system can produce high-quality evidence to support multidisciplinary management of non-melanoma skin cancer and utilizing this information for personalized treatment decisions. PMID: 32395133 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer.
Authors: Gursel SB, Serarslan A, Meydan AD, Okumus N, Yasayacak T Abstract Purpose: The standard treatment for locally advanced stage cervical cancer is definitive radiotherapy, the quality of which affects both survival and side effects. Brachytherapy is a major component of definitive radiotherapy; it is administered using different techniques and applicators. The purpose of this study was to dosimetrically compare tandem ovoid (T-ovoid) and tandem ring (T-ring) brachytherapy treatments. Material and methods: Both applicator sets were applied to the same 20 patients, and treatment plans were made three-dimens...
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Prolonged treatment planning can increase real rectal dose in 3D brachytherapy for cervical cancer.
Conclusions: Extended treatment planning time for brachytherapy due to the changes in topography of small pelvis can lead to different dose in high-risk organs than previously planned. It seems that the most significant changes are related to rectum. PMID: 32395135 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients.
Conclusions: Exclusive short course adjuvant VBT is an effective treatment in patients with early-stage endometrial cancer and provides good outcomes in terms of disease local control and DFS, with low rates of toxicity profile. PMID: 32395136 [PubMed] (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - May 14, 2020 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research