High-dose-rate fractionated brachytherapy monotherapy for localized prostate cancer: a systematic review and meta-analysis
CONCLUSIONS: Fractionated HDR monotherapy is associated with high rates of disease control and low rates of toxicity. Future studies are needed to better define the value of this treatment modality relative to other options.PMID:34484350 | PMC:PMC8407258 | DOI:10.5114/jcb.2021.108590 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Eric M Anderson Sungjin Kim Howard M Sandler Mitchell Kamrava Source Type: research

Eligibility criteria according to EAU/ESTRO/SIOG guidelines for exclusive iodine-125 brachytherapy for intermediate-risk prostate adenocarcinoma patients: impact on relapse-free survival
CONCLUSIONS: Brachytherapy is an effective treatment for selected IR-PCA cases. Patients who were not eligible according to EAU/ESTRO/SIOG guidelines demonstrated a lower RFS.PMID:34484351 | PMC:PMC8407263 | DOI:10.5114/jcb.2021.108592 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sophie Robin Sylvie Chabaud Anne-Agathe Serre B éatrice Bringeon S ébastien Clippe Fran çois Rocher Olivier Desmettre Gabriel Bringeon Fr édéric Gassa Pascal Pommier Source Type: research

Patient-reported quality of life with interstitial partial breast brachytherapy and external beam whole breast radiotherapy: a comparison using propensity-score matching
J Contemp Brachytherapy. 2021 Aug;13(4):387-394. doi: 10.5114/jcb.2021.107690. Epub 2021 Jul 10.ABSTRACTPURPOSE: The aim of this study was to compare patient-reported quality of life (QOL) scores after accelerated partial breast irradiation (APBI) using interstitial brachytherapy vs. external beam whole breast radiotherapy (WBRT) for breast cancer.MATERIAL AND METHODS: Women with breast cancer treated with WBRT or APBI after breast conservation surgery were enrolled in this prospective study. Single cross-sectional QOL assessment was performed using EORTC QLQ-C30 and BR-23 questionnaires. Patients treated with APBI were pr...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Tabassum Wadasadawala Priyamvada Maitre Shwetabh Sinha Vani Parmar Rima Pathak Mithila Gaikar Shalini Verma Rajiv Sarin Source Type: research

The efficacy of iodine-125 interstitial brachytherapy for the treatment of locally advanced adenoid cystic carcinoma of the base of tongue: a non-surgical approach
CONCLUSIONS: The results suggest that iodine-125 interstitial brachytherapy is an effective and safe option for the treatment of primary locally advanced ACC of the base of the tongue, with reasonably satisfactory LC and OS.PMID:34484353 | PMC:PMC8407254 | DOI:10.5114/jcb.2021.108593 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Shuang Dong Wei Li Yan Shi Xiao-Ming Lv Ming-Wei Huang Jian-Guo Zhang Source Type: research

Salvage brachytherapy with or without external beam radiotherapy for oral or oropharyngeal squamous cell carcinomas in previously irradiated areas: carcinologic and toxicity outcomes of 25 patients
CONCLUSIONS: Multimodal treatment, including salvage BT, may offer a curative option for selected patients with an acceptable risk of severe toxicity for the treatment of primary or recurrent tumors in previously irradiated areas.PMID:34484354 | PMC:PMC8407255 | DOI:10.5114/jcb.2021.108594 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Pierre-Marie Pialat Michael Mounie Fabien Podeur Fr édéric Gassa Jean-Philippe Suchaud Bertrand Fleury Severine Racadot Anne-Agathe Serre Pascal Pommier Source Type: research

3D-printed template and optical needle navigation in CT-guided iodine-125 permanent seed implantation
CONCLUSIONS: Seed implantation under combination guidance showed good accuracy, and the actual intra-operative puncture information and post-operative doses were in agreement with those in the pre-operative plan, thereby demonstrating promising prospects for further development.PMID:34484355 | PMC:PMC8407253 | DOI:10.5114/jcb.2021.108595 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Zhe Ji Yuliang Jiang Haitao Sun Yi Chen Fuxin Guo Jinghong Fan Junjie Wang Source Type: research

Clinical outcomes of distal vaginal and vulvar cancer treated with image-guided brachytherapy
CONCLUSIONS: Definitive radiation therapy in the form of EBRT and IGBT provides meaningful loco-regional control in women with distal vaginal and vulvar cancers, with mainly skin and vaginal toxicity.PMID:34484356 | PMC:PMC8407257 | DOI:10.5114/jcb.2021.108596 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Alexander Yaney Erin Healy Xueliang Pan Douglas Martin Allison Quick Source Type: research

Role of non-absorbable oral antibiotics in bowel preparation for intracavitary brachytherapy: effects of rifaximin on rectal dosimetric parameters during vaginal cuff brachytherapy
CONCLUSIONS: Even though the addition of rifaximin to bowel preparation significantly reduced rectal volume, no significant difference was observed in DVH parameters. Therefore, it is recommended that adjuvant vaginal cuff HDR brachytherapy should be performed without the use of rifaximin, until further researches' validate its effects.PMID:34484357 | PMC:PMC8407262 | DOI:10.5114/jcb.2021.108597 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sasan Razmjoo Ali Bagheri Hodjatollah Shahbazian Seyed-Mohammad Hosseini Faezeh Ebrahimian-Tabrizi Source Type: research

Brachytherapy or enucleation in ring melanoma patients: which is better? Preliminary results of the authors' own experiences
CONCLUSIONS: Preliminary observations may suggest that brachytherapy in this rare form of uveal melanoma, such as ring melanoma involving the ciliary body, may be taken into consideration as a useful alternative to enucleation. However, the confirmation of such an approach requires a larger patients' group to be gathered, and also a longer follow-up period. This is especially important in patients with a good baseline visual acuity in the affected eye, or when the neoplasm is present in the remaining eye with vision.PMID:34484358 | PMC:PMC8407261 | DOI:10.5114/jcb.2021.108598 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Anna Markiewicz Karolina Gerba-G órecka Barbara Jakubowska Magdalena De Bicka-Kumela Joanna Kowal Izabella Karska-Basta Konrad Sk órkiewicz Boz Ena Romanowska-Dixon Source Type: research

Advanced dose calculation algorithm in superficial brachytherapy - the impact of tissue inhomogeneity on treatment plan dosimetry
J Contemp Brachytherapy. 2021 Aug;13(4):441-446. doi: 10.5114/jcb.2021.106541. Epub 2021 May 28.ABSTRACTPURPOSE: Given tissue inhomogeneity and lack of backscatter media, superficial brachytherapy necessitates more accurate dosimetry than TG-43 formalism. However, the introduction of modern model-based dose calculation algorithms into clinical practice should be carefully evaluated. The aim of this work was to compare dose distributions calculated with TG-43 and advanced collapsed cone engine (ACE) algorithms for individual multi-catheter moulds, and investigate the impact of target size and the lack of bolus to difference...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Marta Szlag Sylwia Kellas- Śleczka Piotr Wojcieszek Magdalena Stankiewicz Agnieszka Cholewka Agnieszka Pruefer Tomasz Krzysztofiak Piotr Lelek Ma łgorzata Stąpór-Fudzińska Krzysztof Ślosarek Source Type: research

Correlation of total reference air-kerma (TRAK) to prescription isodose surface volume in vaginal cylinder high-dose-rate brachytherapy
CONCLUSIONS: The correlation of TRAK to the vaginal tissue volume encompassed by the prescription dose surface yields a useful predictive equation. The TRAK treatment time relationship enables quick verification of planned treatment time by knowing TRAK in any HDR brachytherapy application.PMID:34484360 | PMC:PMC8407256 | DOI:10.5114/jcb.2021.108599 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Ravindra Yaparpalvi Keyur J Mehta Source Type: research

Unresectable bulky chest wall recurrent breast cancer controlled with CT-guided interstitial high-dose-rate brachytherapy and external beam radiotherapy with adjuvant hormonal therapy - case report
CONCLUSIONS: CT-guided HDR ISBT boost can be a useful modality in individualizing treatment strategies for breast cancer patients with unresectable bulky chest wall recurrence.PMID:34484361 | PMC:PMC8407259 | DOI:10.5114/jcb.2021.108600 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Hiroaki Kunogi I-Chow Hsu Keisuke Sasai Source Type: research

Radioimmunotherapy: future prospects from the perspective of brachytherapy
J Contemp Brachytherapy. 2021 Aug;13(4):458-467. doi: 10.5114/jcb.2021.108601. Epub 2021 Aug 24.ABSTRACTIn combination with radiotherapy, immunotherapy is becoming an increasingly used strategy in treating advanced, recurrent, or metastatic cancer. The evident impact of radiotherapy on local and systemic immune response is an indication of the synergistic effect of these two modalities. There is a strong rationale to combine radiotherapy and immunotherapy to enhance response rates and overcome resistances. Therefore, the combination of radio- and immunotherapy holds a variety of opportunities as well as challenges in treat...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Maximilian Fleischmann Markus Glatzer Claus R ödel Nikolaos Tselis Source Type: research

Additive manufacturing (3D printing) in superficial brachytherapy
J Contemp Brachytherapy. 2021 Aug;13(4):468-482. doi: 10.5114/jcb.2021.108602. Epub 2021 Aug 24.ABSTRACTThe aim of this work is to provide an overview of the current state of additive manufacturing (AM), commonly known as 3D printing, within superficial brachytherapy (BT). Several comprehensive database searches were performed to find publications linked to AM in superficial BT. Twenty-eight core publications were found, which can be grouped under general categories of clinical cases, physical and dosimetric evaluations, proof-of-concept cases, design process assessments, and economic feasibility studies. Each study demons...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Robert Bellis Agata Rembielak Elizabeth A Barnes Moti Paudel Ananth Ravi Source Type: research

The use of high frequency skin ultrasound in non-melanoma skin cancer
J Contemp Brachytherapy. 2021 Aug;13(4):483-491. doi: 10.5114/jcb.2021.108603. Epub 2021 Aug 24.ABSTRACTUltrasound (US) or sonography is the most common diagnostic non-invasive imaging method, which is estimated to account for more than a third of all diagnostic procedures used in medical practice. Traditionally, US frequencies used in diagnostic radiology range from 1 MHz to approximately 16 MHz. Visualization of skin morphology requires US frequencies from 20 to 100 MHz, and is called a "high frequency ultrasound" (HFUS). HFUS has been explored in normal skin and in various skin pathologies. It has been found u...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Artur Bezugly Agata Rembielak Source Type: research

High-dose-rate fractionated brachytherapy monotherapy for localized prostate cancer: a systematic review and meta-analysis
CONCLUSIONS: Fractionated HDR monotherapy is associated with high rates of disease control and low rates of toxicity. Future studies are needed to better define the value of this treatment modality relative to other options.PMID:34484350 | PMC:PMC8407258 | DOI:10.5114/jcb.2021.108590 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Eric M Anderson Sungjin Kim Howard M Sandler Mitchell Kamrava Source Type: research

Eligibility criteria according to EAU/ESTRO/SIOG guidelines for exclusive iodine-125 brachytherapy for intermediate-risk prostate adenocarcinoma patients: impact on relapse-free survival
CONCLUSIONS: Brachytherapy is an effective treatment for selected IR-PCA cases. Patients who were not eligible according to EAU/ESTRO/SIOG guidelines demonstrated a lower RFS.PMID:34484351 | PMC:PMC8407263 | DOI:10.5114/jcb.2021.108592 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sophie Robin Sylvie Chabaud Anne-Agathe Serre B éatrice Bringeon S ébastien Clippe Fran çois Rocher Olivier Desmettre Gabriel Bringeon Fr édéric Gassa Pascal Pommier Source Type: research

Patient-reported quality of life with interstitial partial breast brachytherapy and external beam whole breast radiotherapy: a comparison using propensity-score matching
J Contemp Brachytherapy. 2021 Aug;13(4):387-394. doi: 10.5114/jcb.2021.107690. Epub 2021 Jul 10.ABSTRACTPURPOSE: The aim of this study was to compare patient-reported quality of life (QOL) scores after accelerated partial breast irradiation (APBI) using interstitial brachytherapy vs. external beam whole breast radiotherapy (WBRT) for breast cancer.MATERIAL AND METHODS: Women with breast cancer treated with WBRT or APBI after breast conservation surgery were enrolled in this prospective study. Single cross-sectional QOL assessment was performed using EORTC QLQ-C30 and BR-23 questionnaires. Patients treated with APBI were pr...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Tabassum Wadasadawala Priyamvada Maitre Shwetabh Sinha Vani Parmar Rima Pathak Mithila Gaikar Shalini Verma Rajiv Sarin Source Type: research

The efficacy of iodine-125 interstitial brachytherapy for the treatment of locally advanced adenoid cystic carcinoma of the base of tongue: a non-surgical approach
CONCLUSIONS: The results suggest that iodine-125 interstitial brachytherapy is an effective and safe option for the treatment of primary locally advanced ACC of the base of the tongue, with reasonably satisfactory LC and OS.PMID:34484353 | PMC:PMC8407254 | DOI:10.5114/jcb.2021.108593 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Shuang Dong Wei Li Yan Shi Xiao-Ming Lv Ming-Wei Huang Jian-Guo Zhang Source Type: research

Salvage brachytherapy with or without external beam radiotherapy for oral or oropharyngeal squamous cell carcinomas in previously irradiated areas: carcinologic and toxicity outcomes of 25 patients
CONCLUSIONS: Multimodal treatment, including salvage BT, may offer a curative option for selected patients with an acceptable risk of severe toxicity for the treatment of primary or recurrent tumors in previously irradiated areas.PMID:34484354 | PMC:PMC8407255 | DOI:10.5114/jcb.2021.108594 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Pierre-Marie Pialat Michael Mounie Fabien Podeur Fr édéric Gassa Jean-Philippe Suchaud Bertrand Fleury Severine Racadot Anne-Agathe Serre Pascal Pommier Source Type: research

3D-printed template and optical needle navigation in CT-guided iodine-125 permanent seed implantation
CONCLUSIONS: Seed implantation under combination guidance showed good accuracy, and the actual intra-operative puncture information and post-operative doses were in agreement with those in the pre-operative plan, thereby demonstrating promising prospects for further development.PMID:34484355 | PMC:PMC8407253 | DOI:10.5114/jcb.2021.108595 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Zhe Ji Yuliang Jiang Haitao Sun Yi Chen Fuxin Guo Jinghong Fan Junjie Wang Source Type: research

Clinical outcomes of distal vaginal and vulvar cancer treated with image-guided brachytherapy
CONCLUSIONS: Definitive radiation therapy in the form of EBRT and IGBT provides meaningful loco-regional control in women with distal vaginal and vulvar cancers, with mainly skin and vaginal toxicity.PMID:34484356 | PMC:PMC8407257 | DOI:10.5114/jcb.2021.108596 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Alexander Yaney Erin Healy Xueliang Pan Douglas Martin Allison Quick Source Type: research

Role of non-absorbable oral antibiotics in bowel preparation for intracavitary brachytherapy: effects of rifaximin on rectal dosimetric parameters during vaginal cuff brachytherapy
CONCLUSIONS: Even though the addition of rifaximin to bowel preparation significantly reduced rectal volume, no significant difference was observed in DVH parameters. Therefore, it is recommended that adjuvant vaginal cuff HDR brachytherapy should be performed without the use of rifaximin, until further researches' validate its effects.PMID:34484357 | PMC:PMC8407262 | DOI:10.5114/jcb.2021.108597 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sasan Razmjoo Ali Bagheri Hodjatollah Shahbazian Seyed-Mohammad Hosseini Faezeh Ebrahimian-Tabrizi Source Type: research

Brachytherapy or enucleation in ring melanoma patients: which is better? Preliminary results of the authors' own experiences
CONCLUSIONS: Preliminary observations may suggest that brachytherapy in this rare form of uveal melanoma, such as ring melanoma involving the ciliary body, may be taken into consideration as a useful alternative to enucleation. However, the confirmation of such an approach requires a larger patients' group to be gathered, and also a longer follow-up period. This is especially important in patients with a good baseline visual acuity in the affected eye, or when the neoplasm is present in the remaining eye with vision.PMID:34484358 | PMC:PMC8407261 | DOI:10.5114/jcb.2021.108598 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Anna Markiewicz Karolina Gerba-G órecka Barbara Jakubowska Magdalena De Bicka-Kumela Joanna Kowal Izabella Karska-Basta Konrad Sk órkiewicz Boz Ena Romanowska-Dixon Source Type: research

Advanced dose calculation algorithm in superficial brachytherapy - the impact of tissue inhomogeneity on treatment plan dosimetry
J Contemp Brachytherapy. 2021 Aug;13(4):441-446. doi: 10.5114/jcb.2021.106541. Epub 2021 May 28.ABSTRACTPURPOSE: Given tissue inhomogeneity and lack of backscatter media, superficial brachytherapy necessitates more accurate dosimetry than TG-43 formalism. However, the introduction of modern model-based dose calculation algorithms into clinical practice should be carefully evaluated. The aim of this work was to compare dose distributions calculated with TG-43 and advanced collapsed cone engine (ACE) algorithms for individual multi-catheter moulds, and investigate the impact of target size and the lack of bolus to difference...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Marta Szlag Sylwia Kellas- Śleczka Piotr Wojcieszek Magdalena Stankiewicz Agnieszka Cholewka Agnieszka Pruefer Tomasz Krzysztofiak Piotr Lelek Ma łgorzata Stąpór-Fudzińska Krzysztof Ślosarek Source Type: research

Correlation of total reference air-kerma (TRAK) to prescription isodose surface volume in vaginal cylinder high-dose-rate brachytherapy
CONCLUSIONS: The correlation of TRAK to the vaginal tissue volume encompassed by the prescription dose surface yields a useful predictive equation. The TRAK treatment time relationship enables quick verification of planned treatment time by knowing TRAK in any HDR brachytherapy application.PMID:34484360 | PMC:PMC8407256 | DOI:10.5114/jcb.2021.108599 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Ravindra Yaparpalvi Keyur J Mehta Source Type: research

Unresectable bulky chest wall recurrent breast cancer controlled with CT-guided interstitial high-dose-rate brachytherapy and external beam radiotherapy with adjuvant hormonal therapy - case report
CONCLUSIONS: CT-guided HDR ISBT boost can be a useful modality in individualizing treatment strategies for breast cancer patients with unresectable bulky chest wall recurrence.PMID:34484361 | PMC:PMC8407259 | DOI:10.5114/jcb.2021.108600 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Hiroaki Kunogi I-Chow Hsu Keisuke Sasai Source Type: research

Radioimmunotherapy: future prospects from the perspective of brachytherapy
J Contemp Brachytherapy. 2021 Aug;13(4):458-467. doi: 10.5114/jcb.2021.108601. Epub 2021 Aug 24.ABSTRACTIn combination with radiotherapy, immunotherapy is becoming an increasingly used strategy in treating advanced, recurrent, or metastatic cancer. The evident impact of radiotherapy on local and systemic immune response is an indication of the synergistic effect of these two modalities. There is a strong rationale to combine radiotherapy and immunotherapy to enhance response rates and overcome resistances. Therefore, the combination of radio- and immunotherapy holds a variety of opportunities as well as challenges in treat...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Maximilian Fleischmann Markus Glatzer Claus R ödel Nikolaos Tselis Source Type: research

Additive manufacturing (3D printing) in superficial brachytherapy
J Contemp Brachytherapy. 2021 Aug;13(4):468-482. doi: 10.5114/jcb.2021.108602. Epub 2021 Aug 24.ABSTRACTThe aim of this work is to provide an overview of the current state of additive manufacturing (AM), commonly known as 3D printing, within superficial brachytherapy (BT). Several comprehensive database searches were performed to find publications linked to AM in superficial BT. Twenty-eight core publications were found, which can be grouped under general categories of clinical cases, physical and dosimetric evaluations, proof-of-concept cases, design process assessments, and economic feasibility studies. Each study demons...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Robert Bellis Agata Rembielak Elizabeth A Barnes Moti Paudel Ananth Ravi Source Type: research

The use of high frequency skin ultrasound in non-melanoma skin cancer
J Contemp Brachytherapy. 2021 Aug;13(4):483-491. doi: 10.5114/jcb.2021.108603. Epub 2021 Aug 24.ABSTRACTUltrasound (US) or sonography is the most common diagnostic non-invasive imaging method, which is estimated to account for more than a third of all diagnostic procedures used in medical practice. Traditionally, US frequencies used in diagnostic radiology range from 1 MHz to approximately 16 MHz. Visualization of skin morphology requires US frequencies from 20 to 100 MHz, and is called a "high frequency ultrasound" (HFUS). HFUS has been explored in normal skin and in various skin pathologies. It has been found u...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Artur Bezugly Agata Rembielak Source Type: research

High-dose-rate fractionated brachytherapy monotherapy for localized prostate cancer: a systematic review and meta-analysis
CONCLUSIONS: Fractionated HDR monotherapy is associated with high rates of disease control and low rates of toxicity. Future studies are needed to better define the value of this treatment modality relative to other options.PMID:34484350 | PMC:PMC8407258 | DOI:10.5114/jcb.2021.108590 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Eric M Anderson Sungjin Kim Howard M Sandler Mitchell Kamrava Source Type: research

Eligibility criteria according to EAU/ESTRO/SIOG guidelines for exclusive iodine-125 brachytherapy for intermediate-risk prostate adenocarcinoma patients: impact on relapse-free survival
CONCLUSIONS: Brachytherapy is an effective treatment for selected IR-PCA cases. Patients who were not eligible according to EAU/ESTRO/SIOG guidelines demonstrated a lower RFS.PMID:34484351 | PMC:PMC8407263 | DOI:10.5114/jcb.2021.108592 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sophie Robin Sylvie Chabaud Anne-Agathe Serre B éatrice Bringeon S ébastien Clippe Fran çois Rocher Olivier Desmettre Gabriel Bringeon Fr édéric Gassa Pascal Pommier Source Type: research

Patient-reported quality of life with interstitial partial breast brachytherapy and external beam whole breast radiotherapy: a comparison using propensity-score matching
J Contemp Brachytherapy. 2021 Aug;13(4):387-394. doi: 10.5114/jcb.2021.107690. Epub 2021 Jul 10.ABSTRACTPURPOSE: The aim of this study was to compare patient-reported quality of life (QOL) scores after accelerated partial breast irradiation (APBI) using interstitial brachytherapy vs. external beam whole breast radiotherapy (WBRT) for breast cancer.MATERIAL AND METHODS: Women with breast cancer treated with WBRT or APBI after breast conservation surgery were enrolled in this prospective study. Single cross-sectional QOL assessment was performed using EORTC QLQ-C30 and BR-23 questionnaires. Patients treated with APBI were pr...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Tabassum Wadasadawala Priyamvada Maitre Shwetabh Sinha Vani Parmar Rima Pathak Mithila Gaikar Shalini Verma Rajiv Sarin Source Type: research

The efficacy of iodine-125 interstitial brachytherapy for the treatment of locally advanced adenoid cystic carcinoma of the base of tongue: a non-surgical approach
CONCLUSIONS: The results suggest that iodine-125 interstitial brachytherapy is an effective and safe option for the treatment of primary locally advanced ACC of the base of the tongue, with reasonably satisfactory LC and OS.PMID:34484353 | PMC:PMC8407254 | DOI:10.5114/jcb.2021.108593 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Shuang Dong Wei Li Yan Shi Xiao-Ming Lv Ming-Wei Huang Jian-Guo Zhang Source Type: research

Salvage brachytherapy with or without external beam radiotherapy for oral or oropharyngeal squamous cell carcinomas in previously irradiated areas: carcinologic and toxicity outcomes of 25 patients
CONCLUSIONS: Multimodal treatment, including salvage BT, may offer a curative option for selected patients with an acceptable risk of severe toxicity for the treatment of primary or recurrent tumors in previously irradiated areas.PMID:34484354 | PMC:PMC8407255 | DOI:10.5114/jcb.2021.108594 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Pierre-Marie Pialat Michael Mounie Fabien Podeur Fr édéric Gassa Jean-Philippe Suchaud Bertrand Fleury Severine Racadot Anne-Agathe Serre Pascal Pommier Source Type: research

3D-printed template and optical needle navigation in CT-guided iodine-125 permanent seed implantation
CONCLUSIONS: Seed implantation under combination guidance showed good accuracy, and the actual intra-operative puncture information and post-operative doses were in agreement with those in the pre-operative plan, thereby demonstrating promising prospects for further development.PMID:34484355 | PMC:PMC8407253 | DOI:10.5114/jcb.2021.108595 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Zhe Ji Yuliang Jiang Haitao Sun Yi Chen Fuxin Guo Jinghong Fan Junjie Wang Source Type: research

Clinical outcomes of distal vaginal and vulvar cancer treated with image-guided brachytherapy
CONCLUSIONS: Definitive radiation therapy in the form of EBRT and IGBT provides meaningful loco-regional control in women with distal vaginal and vulvar cancers, with mainly skin and vaginal toxicity.PMID:34484356 | PMC:PMC8407257 | DOI:10.5114/jcb.2021.108596 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Alexander Yaney Erin Healy Xueliang Pan Douglas Martin Allison Quick Source Type: research

Role of non-absorbable oral antibiotics in bowel preparation for intracavitary brachytherapy: effects of rifaximin on rectal dosimetric parameters during vaginal cuff brachytherapy
CONCLUSIONS: Even though the addition of rifaximin to bowel preparation significantly reduced rectal volume, no significant difference was observed in DVH parameters. Therefore, it is recommended that adjuvant vaginal cuff HDR brachytherapy should be performed without the use of rifaximin, until further researches' validate its effects.PMID:34484357 | PMC:PMC8407262 | DOI:10.5114/jcb.2021.108597 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sasan Razmjoo Ali Bagheri Hodjatollah Shahbazian Seyed-Mohammad Hosseini Faezeh Ebrahimian-Tabrizi Source Type: research

Brachytherapy or enucleation in ring melanoma patients: which is better? Preliminary results of the authors' own experiences
CONCLUSIONS: Preliminary observations may suggest that brachytherapy in this rare form of uveal melanoma, such as ring melanoma involving the ciliary body, may be taken into consideration as a useful alternative to enucleation. However, the confirmation of such an approach requires a larger patients' group to be gathered, and also a longer follow-up period. This is especially important in patients with a good baseline visual acuity in the affected eye, or when the neoplasm is present in the remaining eye with vision.PMID:34484358 | PMC:PMC8407261 | DOI:10.5114/jcb.2021.108598 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Anna Markiewicz Karolina Gerba-G órecka Barbara Jakubowska Magdalena De Bicka-Kumela Joanna Kowal Izabella Karska-Basta Konrad Sk órkiewicz Boz Ena Romanowska-Dixon Source Type: research

Advanced dose calculation algorithm in superficial brachytherapy - the impact of tissue inhomogeneity on treatment plan dosimetry
J Contemp Brachytherapy. 2021 Aug;13(4):441-446. doi: 10.5114/jcb.2021.106541. Epub 2021 May 28.ABSTRACTPURPOSE: Given tissue inhomogeneity and lack of backscatter media, superficial brachytherapy necessitates more accurate dosimetry than TG-43 formalism. However, the introduction of modern model-based dose calculation algorithms into clinical practice should be carefully evaluated. The aim of this work was to compare dose distributions calculated with TG-43 and advanced collapsed cone engine (ACE) algorithms for individual multi-catheter moulds, and investigate the impact of target size and the lack of bolus to difference...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Marta Szlag Sylwia Kellas- Śleczka Piotr Wojcieszek Magdalena Stankiewicz Agnieszka Cholewka Agnieszka Pruefer Tomasz Krzysztofiak Piotr Lelek Ma łgorzata Stąpór-Fudzińska Krzysztof Ślosarek Source Type: research

Correlation of total reference air-kerma (TRAK) to prescription isodose surface volume in vaginal cylinder high-dose-rate brachytherapy
CONCLUSIONS: The correlation of TRAK to the vaginal tissue volume encompassed by the prescription dose surface yields a useful predictive equation. The TRAK treatment time relationship enables quick verification of planned treatment time by knowing TRAK in any HDR brachytherapy application.PMID:34484360 | PMC:PMC8407256 | DOI:10.5114/jcb.2021.108599 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Ravindra Yaparpalvi Keyur J Mehta Source Type: research

Unresectable bulky chest wall recurrent breast cancer controlled with CT-guided interstitial high-dose-rate brachytherapy and external beam radiotherapy with adjuvant hormonal therapy - case report
CONCLUSIONS: CT-guided HDR ISBT boost can be a useful modality in individualizing treatment strategies for breast cancer patients with unresectable bulky chest wall recurrence.PMID:34484361 | PMC:PMC8407259 | DOI:10.5114/jcb.2021.108600 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Hiroaki Kunogi I-Chow Hsu Keisuke Sasai Source Type: research

Radioimmunotherapy: future prospects from the perspective of brachytherapy
J Contemp Brachytherapy. 2021 Aug;13(4):458-467. doi: 10.5114/jcb.2021.108601. Epub 2021 Aug 24.ABSTRACTIn combination with radiotherapy, immunotherapy is becoming an increasingly used strategy in treating advanced, recurrent, or metastatic cancer. The evident impact of radiotherapy on local and systemic immune response is an indication of the synergistic effect of these two modalities. There is a strong rationale to combine radiotherapy and immunotherapy to enhance response rates and overcome resistances. Therefore, the combination of radio- and immunotherapy holds a variety of opportunities as well as challenges in treat...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Maximilian Fleischmann Markus Glatzer Claus R ödel Nikolaos Tselis Source Type: research

Additive manufacturing (3D printing) in superficial brachytherapy
J Contemp Brachytherapy. 2021 Aug;13(4):468-482. doi: 10.5114/jcb.2021.108602. Epub 2021 Aug 24.ABSTRACTThe aim of this work is to provide an overview of the current state of additive manufacturing (AM), commonly known as 3D printing, within superficial brachytherapy (BT). Several comprehensive database searches were performed to find publications linked to AM in superficial BT. Twenty-eight core publications were found, which can be grouped under general categories of clinical cases, physical and dosimetric evaluations, proof-of-concept cases, design process assessments, and economic feasibility studies. Each study demons...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Robert Bellis Agata Rembielak Elizabeth A Barnes Moti Paudel Ananth Ravi Source Type: research

The use of high frequency skin ultrasound in non-melanoma skin cancer
J Contemp Brachytherapy. 2021 Aug;13(4):483-491. doi: 10.5114/jcb.2021.108603. Epub 2021 Aug 24.ABSTRACTUltrasound (US) or sonography is the most common diagnostic non-invasive imaging method, which is estimated to account for more than a third of all diagnostic procedures used in medical practice. Traditionally, US frequencies used in diagnostic radiology range from 1 MHz to approximately 16 MHz. Visualization of skin morphology requires US frequencies from 20 to 100 MHz, and is called a "high frequency ultrasound" (HFUS). HFUS has been explored in normal skin and in various skin pathologies. It has been found u...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Artur Bezugly Agata Rembielak Source Type: research

High-dose-rate fractionated brachytherapy monotherapy for localized prostate cancer: a systematic review and meta-analysis
CONCLUSIONS: Fractionated HDR monotherapy is associated with high rates of disease control and low rates of toxicity. Future studies are needed to better define the value of this treatment modality relative to other options.PMID:34484350 | PMC:PMC8407258 | DOI:10.5114/jcb.2021.108590 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Eric M Anderson Sungjin Kim Howard M Sandler Mitchell Kamrava Source Type: research

Eligibility criteria according to EAU/ESTRO/SIOG guidelines for exclusive iodine-125 brachytherapy for intermediate-risk prostate adenocarcinoma patients: impact on relapse-free survival
CONCLUSIONS: Brachytherapy is an effective treatment for selected IR-PCA cases. Patients who were not eligible according to EAU/ESTRO/SIOG guidelines demonstrated a lower RFS.PMID:34484351 | PMC:PMC8407263 | DOI:10.5114/jcb.2021.108592 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Sophie Robin Sylvie Chabaud Anne-Agathe Serre B éatrice Bringeon S ébastien Clippe Fran çois Rocher Olivier Desmettre Gabriel Bringeon Fr édéric Gassa Pascal Pommier Source Type: research

Patient-reported quality of life with interstitial partial breast brachytherapy and external beam whole breast radiotherapy: a comparison using propensity-score matching
J Contemp Brachytherapy. 2021 Aug;13(4):387-394. doi: 10.5114/jcb.2021.107690. Epub 2021 Jul 10.ABSTRACTPURPOSE: The aim of this study was to compare patient-reported quality of life (QOL) scores after accelerated partial breast irradiation (APBI) using interstitial brachytherapy vs. external beam whole breast radiotherapy (WBRT) for breast cancer.MATERIAL AND METHODS: Women with breast cancer treated with WBRT or APBI after breast conservation surgery were enrolled in this prospective study. Single cross-sectional QOL assessment was performed using EORTC QLQ-C30 and BR-23 questionnaires. Patients treated with APBI were pr...
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Tabassum Wadasadawala Priyamvada Maitre Shwetabh Sinha Vani Parmar Rima Pathak Mithila Gaikar Shalini Verma Rajiv Sarin Source Type: research

The efficacy of iodine-125 interstitial brachytherapy for the treatment of locally advanced adenoid cystic carcinoma of the base of tongue: a non-surgical approach
CONCLUSIONS: The results suggest that iodine-125 interstitial brachytherapy is an effective and safe option for the treatment of primary locally advanced ACC of the base of the tongue, with reasonably satisfactory LC and OS.PMID:34484353 | PMC:PMC8407254 | DOI:10.5114/jcb.2021.108593 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Shuang Dong Wei Li Yan Shi Xiao-Ming Lv Ming-Wei Huang Jian-Guo Zhang Source Type: research

Salvage brachytherapy with or without external beam radiotherapy for oral or oropharyngeal squamous cell carcinomas in previously irradiated areas: carcinologic and toxicity outcomes of 25 patients
CONCLUSIONS: Multimodal treatment, including salvage BT, may offer a curative option for selected patients with an acceptable risk of severe toxicity for the treatment of primary or recurrent tumors in previously irradiated areas.PMID:34484354 | PMC:PMC8407255 | DOI:10.5114/jcb.2021.108594 (Source: Journal of Contemporary Brachytherapy)
Source: Journal of Contemporary Brachytherapy - September 6, 2021 Category: Cancer & Oncology Authors: Pierre-Marie Pialat Michael Mounie Fabien Podeur Fr édéric Gassa Jean-Philippe Suchaud Bertrand Fleury Severine Racadot Anne-Agathe Serre Pascal Pommier Source Type: research