Whole ‐exome sequencing of the BDR cohort: Evidence to support the role of the PILRA gene in Alzheimer's disease

ConclusionsIn addition, polygenic risk scores (PRS) were able to distinguish between cases and controls with 83.8% accuracy using 3,268 variants, sex, age at death and APOE ε4 and ε2 status as predictors.This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fnan.12452

Source: Neuropathology and Applied Neurobiology - November 28, 2017 Category: Neurology Authors: Tulsi Patel, Keeley J. Brookes, James Turton, Sultan Chaudhury, Tamar Guetta ‐Baranes, Rita Guerreiro, Jose Bras, Dena Hernandez, Andrew Singleton, Paul T. Francis, John Hardy, Kevin Morgan Tags: Original Article Source Type: research