Different IL-17-secreting TLR(+) T cell subsets are associated with disease activity in multiple sclerosis.

In conclusion, our data suggest that the expansion of different Th17 phenotypes expressing TLR2, 4 and 9 is associated with MS disease activity, and reveals a preferential ability of TLR2 ligand in directly inducing the production of cytokines related to brains lesions and neurological disabilities. This article is protected by copyright. All rights reserved.
PMID: 29168181 [PubMed - as supplied by publisher]

Source: Immunology - November 23, 2017 Category: Allergy & Immunology Authors: Ferreira TB, Hygino J, Wing AC, Kasahara TM, Sacramento PM, Camargo S, Rueda F, Alves-Leon SV, Alvarenga R, Vasconcelos CC, Agrawal A, Gupta S, Bento CAM Tags: Immunology Source Type: research