Total Body Irradiation is Safe and Similarly Effective to Chemotherapy-Only Conditioning in Autologous Stem Cell Transplantation for Mantle Cell Lymphoma Patients

• There was no significant difference in PFS and OS for MCL patients that underwent TBI- versus BEAM-based conditioning.• 5-year PFS was 66% versus 52% (TBI versus BEAM); OS 82% versus 68%, respectively.• Early toxicity, non-relapse mortality, and secondary malignancies were similar between gr oups.

Source: Biology of Blood and Marrow Transplantation - October 20, 2017 Category: Hematology Authors: Yolanda D. Tseng, Philip A. Stevenson, Ryan D. Cassaday, Andrew Cowan, Brian G. Till, Mazyar Shadman, Solomon A. Graf, Ralph Ermoian, Stephen D. Smith, Leona A. Holmberg, Oliver W. Press, Ajay K. Gopal Source Type: research